Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Eric R. Vimr"'
Publikováno v:
Journal of Bacteriology. 198:2803-2809
The sialic acids ( N -acylneuraminates) are a group of nine-carbon keto-sugars existing mainly as terminal residues on animal glycoprotein and glycolipid carbohydrate chains. Bacterial commensals and pathogens exploit host sialic acids for nutrition,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20fce92871ec6ce6b694863358d43eac
https://doi.org/10.1128/jb.00189-16
https://doi.org/10.1128/jb.00189-16
Autor:
Eric R. Vimr
Publikováno v:
ISRN Microbiology
Sialic acids are structurally diverse nine-carbon ketosugars found mostly in humans and other animals as the terminal units on carbohydrate chains linked to proteins or lipids. The sialic acids function in cell-cell and cell-molecule interactions nec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ddf1f07a95c94f087359284f361048
https://doi.org/10.1155/2013/816713
https://doi.org/10.1155/2013/816713
Autor:
Eric R. Vimr, Susan M. Steenbergen
Publikováno v:
Molecular Microbiology
Capsular polysaccharides are important virulence determinants in a wide range of invasive infectious diseases. Although capsule synthesis has been extensively investigated, understanding polysaccharide export from the cytoplasm to the external enviro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257e0da66acf9a658972f6e1bb010c3a
http://europepmc.org/articles/PMC2408645
http://europepmc.org/articles/PMC2408645
Autor:
Susan M. Steenbergen, Eric R. Vimr
Publikováno v:
Molecular Microbiology. 60:828-837
Escherichia coli K1 is part of a reservoir of adherent, invasive facultative pathogens responsible for a wide range of human and animal disease including sepsis, meningitis, urinary tract infection and inflammatory bowel syndrome. A prominent virulen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2377092c3d69e0be8b19fa6876042056
https://doi.org/10.1111/j.1365-2958.2006.05158.x
https://doi.org/10.1111/j.1365-2958.2006.05158.x
Publikováno v:
Molecular Microbiology. 50:961-975
A variety of pathogens or commensals use at least one of four distinct mechanisms for decorating their surfaces with sialic acid as a strategy to avoid, subvert or inhibit host innate immunity. The metabolism of sialic acid thus is central to a range
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02456a88fa524ec7b97e68c58e794950
https://doi.org/10.1046/j.1365-2958.2003.03741.x
https://doi.org/10.1046/j.1365-2958.2003.03741.x
Autor:
Carol A. Lichtensteiger, Eric R. Vimr
Publikováno v:
Veterinary Microbiology. 93:79-87
Haemophilus parasuis, which causes polyserositis, polysynovitis, meningitis, septicemia, and pneumonia in pigs, has emerged as an increasing problem in modern swine production systems. Co-factors for and the pathogenesis of H. parasuis disease are no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bcba92c6a9e016fff32d7a3ecf4e47c
https://doi.org/10.1016/s0378-1135(02)00443-1
https://doi.org/10.1016/s0378-1135(02)00443-1
Autor:
Carol A. Lichtensteiger, Eric R. Vimr
Publikováno v:
Trends in Microbiology. 10:254-257
Most oropharyngeal pathogens express sialic acid units on their surfaces, mimicking the sialyl-rich mucin layer coating epithelial cells and the glycoconjugates present on virtually all host cell surfaces and serum proteins. Unlike the host's cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2257a572251cf5fe52c7c4b8e3f41860
https://doi.org/10.1016/s0966-842x(02)02361-2
https://doi.org/10.1016/s0966-842x(02)02361-2
Autor:
Mingwei Qian, Sucheta Telang, John R. Mahoney, Irwin Law, John W. Eaton, Helen Lundqvist-Gustafsson, Eric R. Vimr
Publikováno v:
The Journal of Infectious Diseases. 184:159-165
For reasons unknown, certain Escherichia coli strains become highly virulent when injected with hemoglobin or other soluble iron sources. Two clinical isolates (virulent and nonvirulent) showed equivalent hemoglobin-mediated growth acceleration in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f703bccfe1924468789040e6538203
https://doi.org/10.1086/322017
https://doi.org/10.1086/322017
Publikováno v:
FEMS Microbiology Letters. 198:125-128
With the exception of the polysialic acid capsule (K1 antigen), little is known about other virulence factors needed for systemic infection by Escherichia coli K1, the leading cause of Gram-negative neonatal meningitis in humans. In this work, the fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be5972939eaf593d14d89ba6bbcea385
https://doi.org/10.1111/j.1574-6968.2001.tb10630.x
https://doi.org/10.1111/j.1574-6968.2001.tb10630.x
Publikováno v:
Molecular Microbiology. 36:1113-1123
Many bacterial commensals and pathogens use the sialic acids as carbon and nitrogen sources. In Escherichia coli, the breakdown of these sugars is catalysed by gene products of the nan (Nacylneuraminate) operon; other microorganisms may use a similar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98aea4e96634c3679a3f52f3c7e51278
https://doi.org/10.1046/j.1365-2958.2000.01925.x
https://doi.org/10.1046/j.1365-2958.2000.01925.x