Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Eric R. May"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Membrane curvature is essential for many cellular structures and processes, and factors such as leaflet asymmetry, lipid composition, and proteins all play important roles. Cardiolipin is the signature lipid of mitochondrial membranes and is
Externí odkaz:
https://doaj.org/article/4411d732a6384f96a6a980dd9e1bcd18
Autor:
Wayne Mitchell, Jeffrey D Tamucci, Emery L Ng, Shaoyi Liu, Alexander V Birk, Hazel H Szeto, Eric R May, Andrei T Alexandrescu, Nathan N Alder
Publikováno v:
eLife, Vol 11 (2022)
Mitochondria play a central role in metabolic homeostasis, and dysfunction of this organelle underpins the etiology of many heritable and aging-related diseases. Tetrapeptides with alternating cationic and aromatic residues such as SS-31 (elamipretid
Externí odkaz:
https://doaj.org/article/365e231213024becb3e445b4fd264d5e
Autor:
Nanami Senoo, Dinesh K. Chinthapalli, Matthew G. Baile, Vinaya K. Golla, Bodhisattwa Saha, Oluwaseun B. Ogunbona, James A. Saba, Teona Munteanu, Yllka Valdez, Kevin Whited, Dror Chorev, Nathan N. Alder, Eric R. May, Carol V. Robinson, Steven M. Claypool
Publikováno v:
bioRxiv
SummaryThe mitochondrial phospholipid cardiolipin (CL) promotes bioenergetics via oxidative phosphorylation (OXPHOS). Three tightly bound CLs are evolutionarily conserved in the ADP/ATP carrier (AAC in yeast; adenine nucleotide translocator, ANT in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62db7af3c461236f7d1ff1a4f2f4668b
https://europepmc.org/articles/PMC10187269/
https://europepmc.org/articles/PMC10187269/
Publikováno v:
Journal of Structural Biology. 215:107964
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b7f41d86b94052c91dacd9dd1274716
https://doi.org/10.1016/j.jsb.2023.107964
https://doi.org/10.1016/j.jsb.2023.107964
Autor:
Giancarlo Montovano, Theresa S. Buckley, Mahmoud Sharawy, Eric R. May, Ganesh S. Anand, Victoria L. Robinson
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::295a1912e4064abbf1cd3559b357133e
https://doi.org/10.1096/fasebj.2022.36.s1.0r518
https://doi.org/10.1096/fasebj.2022.36.s1.0r518
Autor:
Wayne Mitchell, Nicholas A. Eddy, Xianlin Han, Jeffrey D. Tamucci, Murugappan Sathappa, Eric R. May, Kevin J. Boyd, Nathan N. Alder, Hazel H. Szeto, Adrian Coscia, Emily A. Ng, Meixia Pan
Publikováno v:
The Journal of Biological Chemistry
Mitochondrial dysfunction underlies many heritable diseases, acquired pathologies, and aging-related declines in health. Szeto–Schiller (SS) peptides comprise a class of amphipathic tetrapeptides that are efficacious toward a wide array of mitochon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a25e47da785e61e57245ccc7da8257
https://doi.org/10.1074/jbc.ra119.012094
https://doi.org/10.1074/jbc.ra119.012094
Autor:
Wayne Mitchell, Jeffrey D Tamucci, Emery L Ng, Shaoyi Liu, Alexander V Birk, Hazel H Szeto, Eric R May, Andrei T Alexandrescu, Nathan N Alder
Publikováno v:
eLife. 11
Mitochondria play a central role in metabolic homeostasis, and dysfunction of this organelle underpins the etiology of many heritable and aging-related diseases. Tetrapeptides with alternating cationic and aromatic residues such as SS-31 (elamipretid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18cd2ba1aece8d87091e790acf1b15dc
https://pubmed.ncbi.nlm.nih.gov/35913044
https://pubmed.ncbi.nlm.nih.gov/35913044
Autor:
Andrei T. Alexandrescu, Wayne Mitchell, Eric R. May, Nathan N. Alder, Hazel H. Szeto, Jeffrey D. Tamucci, Emery L. Ng, Shaoyi Liu
Mitochondria play a central role in metabolic homeostasis; hence, dysfunction of this organelle underpins the etiology of many heritable and aging-related diseases. Mitochondria-targeted tetrapeptides with alternating cationic and aromatic residues,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0833891c4668ab92e41e8dafcab1d8b
https://doi.org/10.1101/2021.11.08.467832
https://doi.org/10.1101/2021.11.08.467832
Publikováno v:
Protein Sci
The Orange Carotenoid Protein (OCP) is responsible for nonphotochemical quenching (NPQ) in cyanobacteria, a defense mechanism against potentially damaging effects of excess light conditions. This soluble two-domain protein undergoes profound conforma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb6132ce100080c957a771e9a6b78e6
https://doi.org/10.26434/chemrxiv-2021-cwhv4
https://doi.org/10.26434/chemrxiv-2021-cwhv4
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 3 (2015)
Norwalk virus causes severe gastroenteritis for which there is currently no specific anti-viral therapy. A stage of the infection process is uncoating of the protein capsid to expose the viral genome and allow for viral replication. A mechanical char
Externí odkaz:
https://doaj.org/article/17d045ca110f498584f576ddb51c2ad2