Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eric R. Brooks"'
Publikováno v:
eLife, Vol 9 (2020)
Neural tube closure defects are a major cause of infant mortality, with exencephaly accounting for nearly one-third of cases. However, the mechanisms of cranial neural tube closure are not well understood. Here, we show that this process involves a t
Externí odkaz:
https://doaj.org/article/9ebcc567e1254bed8c0d7b2d095daa52
Autor:
Mei-I Chung, Taejoon Kwon, Fan Tu, Eric R Brooks, Rakhi Gupta, Matthew Meyer, Julie C Baker, Edward M Marcotte, John B Wallingford
Publikováno v:
eLife, Vol 3 (2014)
The mechanisms linking systems-level programs of gene expression to discrete cell biological processes in vivo remain poorly understood. In this study, we have defined such a program for multi-ciliated epithelial cells (MCCs), a cell type critical fo
Externí odkaz:
https://doaj.org/article/c3a6cc19af7c42d98759270e42cfea86
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Neural tube closure defects are a major cause of infant mortality, with exencephaly accounting for nearly one-third of cases. However, the mechanisms of cranial neural tube closure are not well understood. Here we show that this process involves a ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbed3398049bb3894592cde4f89efa8e
https://elifesciences.org/articles/60234
https://elifesciences.org/articles/60234
Autor:
John B. Wallingford, Eric R. Brooks
Publikováno v:
Current Biology. 24(19):R973-R982
Cilia are microtubule based cellular projections that serve a wide variety of essential functions in animal cells. Defects in cilia structure or function have recently emerged as etiological mechanisms underpinning diverse human diseases. While many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144fd67743bb6362185ce7a0599f275c
Autor:
Eric R. Brooks, John B. Wallingford
Publikováno v:
The Journal of Cell Biology
The planar cell polarity effector Fuz is required for normal particle dynamics of the intraflagellar transport system, specifically in the retrograde transport of proteins.
Cilia play key roles in development and homeostasis, and defects in cili
Cilia play key roles in development and homeostasis, and defects in cili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fabf1353e7591ca12945d19b790870be
https://doi.org/10.1083/jcb.201204072
https://doi.org/10.1083/jcb.201204072
Autor:
John B. Wallingford, Eric R. Brooks
Cilia are key organelles in development and homeostasis. The ever-expanding complement of cilia associated proteins necessitates rapid and tractable models for in vivo functional investigation. Xenopus laevis provides an attractive model for such stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8403a5b839a61b641213e98ce06d7233
https://europepmc.org/articles/PMC4433029/
https://europepmc.org/articles/PMC4433029/
Autor:
Edward M. Marcotte, Julie C. Baker, Taejoon Kwon, Rakhi Gupta, Fan Tu, Mei I. Chung, John B. Wallingford, Eric R. Brooks, Matthew D. Meyer
Publikováno v:
eLife
eLife, Vol 3 (2014)
eLife, Vol 3 (2014)
The mechanisms linking systems-level programs of gene expression to discrete cell biological processes in vivo remain poorly understood. In this study, we have defined such a program for multi-ciliated epithelial cells (MCCs), a cell type critical fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb8d12a73b13dc55c92ffce55dc99bd
https://doi.org/10.7554/elife.01439
https://doi.org/10.7554/elife.01439
Autor:
John B. Wallingford, Eric R. Brooks
Publikováno v:
Cilia
Background Cilia are small, microtubule-based protrusions important for development and homeostasis. We recently demonstrated that the planar cell polarity effector protein Fuz is a critical regulator of axonemal intraflagellar transport dynamics and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8931f435c07efad0821084e26286a3