Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Eric R Schreiter"'
Publikováno v:
eLife, Vol 9 (2020)
Understanding how the brain encodes and processes information requires the recording of neural activity that underlies different behaviors. Recent efforts in fluorescent protein engineering have succeeded in developing powerful tools for visualizing
Externí odkaz:
https://doaj.org/article/640c0b46a278434f91312c2b1c0f9fa9
Autor:
Joshua S. Selfe, Teresa J. S. Steyn, Eran F. Shorer, Richard J. Burman, Kira M. Düsterwald, Ariel Z. Kraitzick, Ahmed S. Abdelfattah, Eric R. Schreiter, Sarah E. Newey, Colin J. Akerman, Joseph V. Raimondo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Ionic driving forces provide the net electromotive force for ion movement across receptors, channels, and transporters, and are a fundamental property of all cells. In the nervous system, fast synaptic inhibition is mediated by chloride perm
Externí odkaz:
https://doaj.org/article/c0646bb3d3a84e5dae514f6b764b6a3a
Autor:
Hod Dana, Boaz Mohar, Yi Sun, Sujatha Narayan, Andrew Gordus, Jeremy P Hasseman, Getahun Tsegaye, Graham T Holt, Amy Hu, Deepika Walpita, Ronak Patel, John J Macklin, Cornelia I Bargmann, Misha B Ahrens, Eric R Schreiter, Vivek Jayaraman, Loren L Looger, Karel Svoboda, Douglas S Kim
Publikováno v:
eLife, Vol 5 (2016)
Genetically encoded calcium indicators (GECIs) allow measurement of activity in large populations of neurons and in small neuronal compartments, over times of milliseconds to months. Although GFP-based GECIs are widely used for in vivo neurophysiolog
Externí odkaz:
https://doaj.org/article/ab34ae2c5e2b47b2a8b288f3d69d627e
Autor:
Mark J Henderson, Heather A Baldwin, Christopher A Werley, Stefano Boccardo, Leslie R Whitaker, Xiaokang Yan, Graham T Holt, Eric R Schreiter, Loren L Looger, Adam E Cohen, Douglas S Kim, Brandon K Harvey
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139273 (2015)
Endoplasmic reticulum calcium homeostasis is critical for cellular functions and is disrupted in diverse pathologies including neurodegeneration and cardiovascular disease. Owing to the high concentration of calcium within the ER, studying this subce
Externí odkaz:
https://doaj.org/article/161ea35e86594287bc3d469f5096851a
Autor:
Jasper eAkerboom, Nicole eCarreras Calderón, Lin eTian, Sebastian eWabnig, Matthias ePrigge, Johan eTolö, Andrew eGordus, Michael B Orger, Kristen E Severi, John J Macklin, Ronak ePatel, Stefan R Pulver, Trevor J Wardill, Elisabeth eFischer, Christina eSchüler, Tsai-Wen eChen, Karen S Sarkisyan, Jonathan S Marvin, Cornelia I Bargmann, Douglas S Kim, Sebastian eKügler, Leon eLagnado, Peter eHegemann, Alexander eGottschalk, Eric R Schreiter, Loren L Looger
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 6 (2013)
Genetically encoded calcium indicators (GECIs) are powerful tools for systems neuroscience. Here we describe red, single-wavelength GECIs, RCaMPs, engineered from circular permutation of the thermostable red fluorescent protein mRuby. High-resolution
Externí odkaz:
https://doaj.org/article/46e541bc41ce4dd2bdcb29ec64a7b4d7
Autor:
Trevor J Wardill, Tsai-Wen Chen, Eric R Schreiter, Jeremy P Hasseman, Getahun Tsegaye, Benjamin F Fosque, Reza Behnam, Brenda C Shields, Melissa Ramirez, Bruce E Kimmel, Rex A Kerr, Vivek Jayaraman, Loren L Looger, Karel Svoboda, Douglas S Kim
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77728 (2013)
Fluorescent protein-based sensors for detecting neuronal activity have been developed largely based on non-neuronal screening systems. However, the dynamics of neuronal state variables (e.g., voltage, calcium, etc.) are typically very rapid compared
Externí odkaz:
https://doaj.org/article/260c05b0e92b4cd0a03c4417df7ccb10
Autor:
Ahmed S. Abdelfattah, Jihong Zheng, Amrita Singh, Yi-Chieh Huang, Daniel Reep, Getahun Tsegaye, Arthur Tsang, Benjamin J. Arthur, Monika Rehorova, Carl V.L. Olson, Yichun Shuai, Lixia Zhang, Tian-Ming Fu, Daniel E. Milkie, Maria V. Moya, Timothy D. Weber, Andrew L. Lemire, Christopher A. Baker, Natalie Falco, Qinsi Zheng, Jonathan B. Grimm, Mighten C. Yip, Deepika Walpita, Martin Chase, Luke Campagnola, Gabe J. Murphy, Allan M. Wong, Craig R. Forest, Jerome Mertz, Michael N. Economo, Glenn C. Turner, Minoru Koyama, Bei-Jung Lin, Eric Betzig, Ondrej Novak, Luke D. Lavis, Karel Svoboda, Wyatt Korff, Tsai-Wen Chen, Eric R. Schreiter, Jeremy P. Hasseman, Ilya Kolb
Publikováno v:
Neuron. 111:1547-1563.e9
Autor:
Adam J. Berro, Natalie Falco, Luke D. Lavis, Hersh K. Bhargava, Benjamien Moeyaert, Mariam Chupanova, Eric R. Schreiter, Claire Deo, Ahmed S. Abdelfattah, Helen Farrants
Publikováno v:
Nature Chemical Biology. 17:718-723
Functional imaging using fluorescent indicators has revolutionized biology, but additional sensor scaffolds are needed to access properties such as bright, far-red emission. Here, we introduce a new platform for 'chemigenetic' fluorescent indicators,
Autor:
Loren L. Looger, Douglas S. Kim, Eric R. Schreiter, Allan M. Wong, Chi-Yu Lee, Abhi Aggarwal, Jeong Jun Kim, Emiliano Jimenez Marquez, Allison M. Ahrens, Jonathan S. Marvin, Kaspar Podgorski, Yajie Liang, Daniel Bushey, Manuel A. Mohr, John J. Macklin, Getahun Tsegaye, Jerry L. Chen, Ronak Patel, Arthur Tsang
Publikováno v:
Nature methods
Femtosecond lasers at fixed wavelengths above 1,000 nm are powerful, stable and inexpensive, making them promising sources for two-photon microscopy. Biosensors optimized for these wavelengths are needed for both next-generation microscopes and affor
Autor:
Arthur Tsang, Sam Wang, Jing Lim, Christopher J. Obara, Jeremy P. Hasseman, Eric R. Schreiter, Yan Zhang, Misha B. Ahrens, Ziqiang Wei, Karel Svoboda, Daniel Bushey, Gerard Joey Broussard, Ronak Patel, Wyatt Korff, Loren L. Looger, Rongwei Zhang, Yajie Liang, Márton Rózsa, Glenn C. Turner, Jihong Zheng, Getahun Tsegaye, Ilya Kolb, Sujatha Narayan, Daniel Reep
Calcium imaging with protein-based indicators is widely used to follow neural activity in intact nervous systems. The popular GCaMP indicators are based on the calcium-binding protein calmodulin and the RS20 peptide. These sensors report neural activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26b85ade8988fc48fc1939f95d2d4683
https://doi.org/10.21203/rs.3.rs-1061816/v1
https://doi.org/10.21203/rs.3.rs-1061816/v1