Výsledky vyhledávání - "Eric R Lemmer"

Drug-Induced Liver Injury: Review Article

Autor: Karl J. D’Silva, Stephen Kim, Eric R. Lemmer, Wissam Bleibel

Publikováno v: Digestive Diseases and Sciences. 52:2463-2471

Drug-induced liver injury (DILI) is a term that describes abnormalities in liver function tests (LFTs) related to medication intake. DILI, a subtype of hepatotoxicity, does not include hepatic injuries related to nonmedicinal compounds, including her

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b624d5cd6fc00e9c6892a51db78ea911
https://doi.org/10.1007/s10620-006-9472-y

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Molecular Diagnosis of Chronic Liver Disease and Hepatocellular Carcinoma: The Potential of Gene Expression Profiling

Autor: Scott L. Friedman, Eric R. Lemmer, Josep M. Llovet

Publikováno v: Seminars in Liver Disease. 26:373-384

Gene expression profile analysis through DNA microarrays and other high-throughput technologies permit simultaneous investigation of all genes within a biologic sample, providing a snapshot of the transcriptional state of healthy or diseased tissue.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acea7d2b0585503b5701b6e791a69b51
https://doi.org/10.1055/s-2006-951604

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Intact signaling by transforming growth factor β is not required for termination of liver regeneration in mice

Autor: Jonas Larsson, Shoshiro Oe, Elizabeth A. Conner, Snorri S. Thorgeirsson, Eric R. Lemmer, Valentina M. Factor, Per Levéen, Stefan Karlsson

Publikováno v: Hepatology. 40:1098-1105

Transforming growth factor beta (TGF-beta) is a potent inhibitor of hepatocyte proliferation in vitro and is suggested to be a key negative regulator of liver growth. To directly address the role of TGF-beta signaling in liver regeneration in vivo, t

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https://doi.org/10.1002/hep.20426

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Dual functions of E2F-1 in a transgenic mouse model of liver carcinogenesis

Autor: Masako Omori, Eric R Lemmer, Valentina M. Factor, Snorri S. Thorgeirsson, Elizabeth A. Conner, Peter J. Wirth

Publikováno v: Oncogene. 19:5054-5062

Deregulation of E2F transcriptional control has been implicated in oncogenic transformation. Consistent with this idea, we recently demonstrated that during hepatocarcinogenesis in c-myc/TGFalpha double transgenic mice, there is increased expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a18331c1f15303e0a18452d094606c
https://doi.org/10.1038/sj.onc.1203885

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The effects of dietary iron overload on fumonisin B1-induced cancer promotion in the rat liver

Autor: Eric R. Lemmer, Walter F. O. Marasas, Enid G. Shephard, J. Peter Cruse, Ralph E. Kirsch, Stefan Abel, Wentzel C. A. Gelderblom, Beverley L Seymour, Pauline de la M. Hall

Publikováno v: Cancer Letters. 146:207-215

The present study was performed to determine whether excess hepatic iron modulates the cancer-initiating and promoting properties of FB1. Thirty-eight male F344 rats were divided into four dietary treatment groups: (i) control diet (AIN, n = 8); (ii)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7609f85c3cfa4875ff5b92664fb3232f
https://doi.org/10.1016/s0304-3835(99)00274-8

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Histopathology and gene expression changes in rat liver during feeding of fumonisin B1, a carcinogenic mycotoxin produced by Fusarium moniliforme

Autor: Ralph E. Kirsch, Snorri S. Thorgeirsson, Rochelle A. Barnard, Wentzel C. A. Gelderblom, Masako Omori, Walter F. O. Marasas, J. Peter Cruse, Pauline de la M. Hall, Eric R. Lemmer, Enid G. Shephard, N Omori

Publikováno v: Carcinogenesis. 20:817-824

Fumonisin B1 (FB1) is a carcinogenic mycotoxin produced by the fungus Fusarium moniliforme in corn. Feeding of FB1 to rats causes acute liver injury, chronic liver injury progressing to cirrhosis, and sometimes terminates in hepatocellular carcinoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de6e3ef1d333ca0a897206b9e6eed89
https://doi.org/10.1093/carcin/20.5.817

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Contents, Vol. 13, 1996

Autor: Yasutsugu Shoji, Joji Utsunomiya, Tetsuya Hirano, Shlomo Berliner, Shalom Watemberg, Michael Voigt, U. Schöffel, Samia Hutba, H.G. Beger, Yoichi Saitoh, E. Eleftheriadis, Andrea Amorosi, P. Berberat, Christoforos Stoupis, Moshe Aronson, Dina Lev, Masato Kusunoki, Daniela Massi, Roberto De Giorgio, Ofer Landau, Andrea Valeri, H. Friess, Mauro Pirovino, K. Kotzampassi, Nadir Arber, J.U. Bascom, Hiroki Ikeuchi, E.H. Farthmann, Hitoshi Yoshikawa, Jake E. J. Krige, Simon Brönnimann, Richard Hift, Lucio Gullo, Masahiro Yamamoto, Abu-Abid Subchi, M.W. Büchler, Markus W. Büchler, Hirohiko Onoyama, Eric R. Lemmer, Karl Søndenaa, Takehira Yamamura, S. Caplin, Wendy Spearman, T Okamoto, L. Krähenbühl, Raffaele Pezzilli, J.-C. Givel, Hans U. Baer, Hidenori Yanagi, Arthur Zimmermann, F.-A. Wassmer, Joseph M. Klausner

Publikováno v: Digestive Surgery. 13:I-IV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::309ee15c435ca8ca8748b3232f107689
https://doi.org/10.1159/000172484

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Recurrence patterns after first resection for stricturing or penetrating Crohn's disease

Autor: David B. Sachar, Christopher Ibrahim, Yair Edden, Thomas A. Ullman, Joel J. Bauer, Esther Roth, Eric R. Lemmer, Julie Ciardulo, Adrian J. Greenstein

Publikováno v: Inflammatory bowel diseases. 15(7)

Background: Crohn's disease (CD) usually recurs after resection, but the factors associated with this risk remain obscure. We set out to determine the role of stricturing (Montreal Classification B2) versus penetrating (Classification B3) disease beh

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https://pubmed.ncbi.nlm.nih.gov/19229992

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Zebras and bergkwaggas--the case for research on rare and very rare genetic diseases in South Africa

Autor: Eric R, Lemmer

Publikováno v: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 95(11)

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https://pubmed.ncbi.nlm.nih.gov/16344866

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Prolonged Survival following Portoenterostomy for Biliary Atresia

Autor: Eric R. Lemmer, Jake E. J. Krige, Richard Hift, Wendy Spearman, Michael Voigt

Publikováno v: Scopus-Elsevier

We report a case of prolonged survival following hepatic portoenterostomy for biliary atresia, which was performed 3 years before Kasai described the operation. To our knowledge he represents the olde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72bda1bc07abd12ec54cac21eac2611
https://doi.org/10.1159/000172496

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