Zobrazeno 1 - 10
of 612
pro vyhledávání: '"Eric R Kandel"'
Autor:
Yun-Beom Choi, Beena M Kadakkuzha, Xin-An Liu, Komolitdin Akhmedov, Eric R Kandel, Sathyanarayanan V Puthanveettil
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103004 (2014)
Patients with Huntington's disease exhibit memory and cognitive deficits many years before manifesting motor disturbances. Similarly, several studies have shown that deficits in long-term synaptic plasticity, a cellular basis of memory formation and
Externí odkaz:
https://doaj.org/article/f56bf8e4997d4d92ab85e16d2314da7e
Autor:
Isabel A Muzzio, Liat Levita, Jayant Kulkarni, Joseph Monaco, Clifford Kentros, Matthew Stead, Larry F Abbott, Eric R Kandel
Publikováno v:
PLoS Biology, Vol 7, Iss 6, p e1000140 (2009)
A key question in the analysis of hippocampal memory relates to how attention modulates the encoding and long-term retrieval of spatial and nonspatial representations in this region. To address this question, we recorded from single cells over a peri
Externí odkaz:
https://doaj.org/article/bf4243c096be4c6cbbc9e6e76ed26e83
Autor:
Eric R. Kandel
One day in 1996, the neuroscientist Eric R. Kandel took a call from his program officer at the National Institute of Mental Health, who informed him that he had been awarded a key grant. Also, the officer said, he and his colleagues thought Kandel wo
Autor:
Eric R. Kandel
Are art and science separated by an unbridgeable divide? Can they find common ground? In this new book, neuroscientist Eric R. Kandel, whose remarkable scientific career and deep interest in art give him a unique perspective, demonstrates how science
Autor:
Bettina Drisaldi, Luca Colnaghi, Amir Levine, YanYou Huang, Anna M. Snyder, Daniel J. Metzger, Martin Theis, Denise B. Kandel, Eric R. Kandel, Luana Fioriti
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
A recurrent and devastating feature of addiction to a drug of abuse is its persistence, which is mediated by maladaptive long-term memories of the highly pleasurable experience initially associated with the consumption of the drug. We have recently f
Externí odkaz:
https://doaj.org/article/eecf03f4d98040a38043da74d23a3a4a
Autor:
Philippe A. Melas, Johanna S. Qvist, Matteo Deidda, Chirag Upreti, Ya Bin Wei, Fabrizio Sanna, Walter Fratta, Maria Scherma, Paola Fadda, Denise B. Kandel, Eric R. Kandel
Publikováno v:
Cell Reports, Vol 22, Iss 11, Pp 2909-2923 (2018)
Summary: Reduced eukaryotic Initiation Factor 2 (eIF2)α phosphorylation (p-eIF2α) enhances protein synthesis, memory formation, and addiction-like behaviors. However, p-eIF2α has not been examined with regard to psychoactive cannabinoids and cross
Externí odkaz:
https://doaj.org/article/99f543662ec643cbac9907788fd6f958
Publikováno v:
Cell Reports, Vol 22, Iss 1, Pp 59-71 (2018)
Summary: Stress granules are non-membranous structures that transiently form in the cytoplasm during cellular stress, where they promote translational repression of non-essential RNAs and modulate cell signaling by sequestering key signal transductio
Externí odkaz:
https://doaj.org/article/309cbc90d24943dfbe4c74f267384bf0
Publikováno v:
Cell Reports, Vol 28, Iss 11, Pp 2955-2965.e3 (2019)
Summary: Long-term sensitization of the gill withdrawal reflex in Aplysia requires heterosynaptic, modulatory input that is mediated in part by the growth of new synaptic connections between sensory neurons and their follower cells (intrinsic mediati
Externí odkaz:
https://doaj.org/article/4ef842c5e69147d8a0f16f14125b16fd
Autor:
Arun Asok, Joud Hijazi, Lucas R. Harvey, Stylianos Kosmidis, Eric R. Kandel, Joseph B. Rayman
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
The generalization of fear is adaptive in that it allows an animal to respond appropriately to novel threats that are not identical to previous experiences. In contrast, the overgeneralization of fear is maladaptive and is a hallmark of post-traumati
Externí odkaz:
https://doaj.org/article/742b3b7608f44e3082dbb0ecd5ded6ea
Publikováno v:
Cell Reports, Vol 26, Iss 11, Pp 2970-2983.e4 (2019)
Summary: TIA1 is a prion-related RNA-binding protein whose capacity to form various types of intracellular aggregates has been implicated in neurodegenerative disease. However, its role in normal brain function is poorly understood. Here, we show tha
Externí odkaz:
https://doaj.org/article/f02174dfd2cb4db69e2e61d7786aa680