Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Eric P, Brown"'
Autor:
Hannah L. Mackay, Helen R. Stone, George E. Ronson, Katherine Ellis, Alexander Lanz, Yara Aghabi, Alexandra K. Walker, Katarzyna Starowicz, Alexander J. Garvin, Patrick Van Eijk, Stefan A. Koestler, Elizabeth J. Anthony, Ann Liza Piberger, Anoop S. Chauhan, Poppy Conway-Thomas, Alina Vaitsiankova, Sobana Vijayendran, James F. Beesley, Eva Petermann, Eric J. Brown, Ruth M. Densham, Simon H. Reed, Felix Dobbs, Marco Saponaro, Joanna R. Morris
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Mammalian DNA replication relies on various DNA helicase and nuclease activities to ensure accurate genetic duplication, but how different helicase and nuclease activities are properly directed remains unclear. Here, we identify the ubiquiti
Externí odkaz:
https://doaj.org/article/28ce5cbc0af0403c82bcaf2f474d55ce
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background RNA–DNA hybrids or R-loops are associated with deleterious genomic instability and protective immunoglobulin class switch recombination (CSR). However, the underlying phenomenon regulating the two contrasting functions of R-loop
Externí odkaz:
https://doaj.org/article/7b15e100421340b5a3a8e3d42ac8fe09
Autor:
Niloofar Radgoudarzi, BS, Shahin Hallaj, MD, Michael V. Boland, MD, PhD, Brian Stagg, MD, Sophia Y. Wang, MD, MS, Benjamin Xu, MD, PhD, Swarup S. Swaminathan, MD, Eric N. Brown, MD, PhD, Aiyin Chen, MD, Catherine Q. Sun, MD, Dilru C. Amarasekera, MD, Jonathan S. Myers, MD, Murtaza Saifee, MD, William Halfpenny, MB BChir, MEng, Keri Dirkes, MPH, Linda Zangwill, PhD, Kerry E. Goetz, PhD, MS, Michelle Hribar, PhD, MS, Sally L. Baxter, MD, MSc
Publikováno v:
Ophthalmology Science, Vol 4, Iss 6, Pp 100621- (2024)
Externí odkaz:
https://doaj.org/article/6dd36fedf8a9498485d34771e7435d81
Autor:
Wei Wang, Gillian Strudwick, Dandan Xu, Chantal F Ski, David R Thompson, Terri Rodak, Lisa D Hawke, Eric E Brown, David Castle, Anh T P Nguyen, Susan Deuville, Suzie Goulding, Susan L Rossell
Publikováno v:
BMJ Mental Health, Vol 27, Iss 1 (2024)
Aims This systematic review aims to identify and synthesise the publicly available research testing treatments for mental health, cognition and psychological well-being in long COVID.Methods The following databases and repositories were searched in O
Externí odkaz:
https://doaj.org/article/9e0aacd0555142e5989b5f358a57e187
Autor:
Kenneth Rachwalski, Sean J. Madden, Nicole Ritchie, Shawn French, Timsy Bhando, Adele Girgis-Gabardo, Megan Tu, Rodion Gordzevich, Rowan Ives, Amelia B.Y. Guo, Jarrod W. Johnson, Yiming Xu, Sharookh B. Kapadia, Jakob Magolan, Eric D. Brown
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110894- (2024)
Summary: The increasing prevalence of antibiotic resistance demands the discovery of antibacterial chemical scaffolds with unique mechanisms of action. Phenotypic screening approaches, such as the use of reporters for bacterial cell stress, offer pro
Externí odkaz:
https://doaj.org/article/632df03525ba4e1abf66b25ee4e9f31f
Autor:
Zhao Chen, Magaly Toro, Andrea I. Moreno-Switt, Aiko D. Adell, Enrique J. Delgado-Suárez, Raquel R. Bonelli, Celso J. B. Oliveira, Angélica Reyes-Jara, Xinyang Huang, Brett Albee, Christopher J. Grim, Marc Allard, Sandra M. Tallent, Eric W. Brown, Rebecca L. Bell, Jianghong Meng
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 5 (2024)
ABSTRACTSurface waters are considered ecological habitats where Salmonella enterica can persist and disseminate to fresh produce production systems. This study aimed to explore the genomic profiles of S. enterica serotypes Typhimurium, Newport, and I
Externí odkaz:
https://doaj.org/article/ee0e22912a264a83992c8986b9795194
Autor:
Shawna Zhu, Mary Kate Alexander, Telmo O. Paiva, Kenneth Rachwalski, Anh Miu, Yiming Xu, Vishal Verma, Mike Reichelt, Yves F. Dufrêne, Eric D. Brown, Georgina Cox
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109592- (2024)
Summary: The Escherichia coli outer membrane channel TolC complexes with several inner membrane efflux pumps to export compounds across the cell envelope. All components of these complexes are essential for robust efflux activity, yet E. coli is more
Externí odkaz:
https://doaj.org/article/d3e67c91d4b449098b626ba5898e7760
Autor:
Shawn French, Amelia Bing Ya Guo, Michael J. Ellis, Julia P. Deisinger, Jarrod W. Johnson, Kenneth Rachwalski, Zoë A. Piquette, Telmah Lluka, Miranda Zary, Sineli Gamage, Jakob Magolan, Eric D. Brown
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114053- (2024)
Summary: In the search for much-needed new antibacterial chemical matter, a myriad of compounds have been reported in academic and pharmaceutical screening endeavors. Only a small fraction of these, however, are characterized with respect to mechanis
Externí odkaz:
https://doaj.org/article/8379235328b9489c8577896cefbc3713
Autor:
Oswaldo Partida-Rodríguez, Eric M Brown, Sarah E Woodward, Mihai Cirstea, Lisa A Reynolds, Charisse Petersen, Stefanie L Vogt, Jorge Peña-Díaz, Lisa Thorson, Marie-Claire Arrieta, Eric G Hernández, Liliana Rojas-Velázquez, Patricia Moran, Enrique González Rivas, Angélica Serrano-Vázquez, Horacio Pérez-Juárez, Javier Torres, Cecilia Ximénez, B B Finlay
Publikováno v:
PLoS ONE, Vol 19, Iss 10, p e0312775 (2024)
Intestinal parasites are part of the intestinal ecosystem and have been shown to establish close interactions with the intestinal microbiota. However, little is known about the influence of intestinal protozoa on the regulation of the immune response
Externí odkaz:
https://doaj.org/article/59800aa70cce4bed8eb3aa1fafc82b6b
Autor:
Mark W Urban, Brittany A Charsar, Nicolette M Heinsinger, Shashirekha S Markandaiah, Lindsay Sprimont, Wei Zhou, Eric V Brown, Nathan T Henderson, Samantha J Thomas, Biswarup Ghosh, Rachel E Cain, Davide Trotti, Piera Pasinelli, Megan C Wright, Matthew B Dalva, Angelo C Lepore
Publikováno v:
eLife, Vol 12 (2024)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motor neuron loss. Importantly, non-neuronal cell types such as astrocytes also play significant roles in disease pathogenesis. However, mechanisms of astrocyte contr
Externí odkaz:
https://doaj.org/article/018e0a8bf2cb4c7db4d6c298aaf9f962