Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Eric Ortlund"'
Autor:
Anamika Patel, Sanjeev Kumar, Lilin Lai, Meredith Keen, Rajesh Valanparambil, Chennareddy Chakravarthy, Zane Laughlin, Filipp Frank, Narayanaiah Cheedarla, Hans P. Verkerke, Andrew S. Neish, John D. Roback, Carl W. Davis, Jens Wrammert, Amit Sharma, Rafi Ahmed, Mehul S. Suthar, Kaja Murali-Krishna, Anmol Chandele, Eric Ortlund
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113150- (2023)
Summary: The pairing of antibody genes IGHV2-5/IGLV2-14 is established as a public immune response that potently cross-neutralizes SARS-CoV-2 variants, including Omicron, by targeting class-3/RBD-5 epitopes in the receptor binding domain (RBD). LY-Co
Externí odkaz:
https://doaj.org/article/cbf70641487d4fceb0c6382baa272483
Autor:
Richard Creager, John Blackwood, Thomas Pribyl, Leda Bassit, Anuradha Rao, Morgan Greenleaf, Filipp Frank, Wilbur Lam, Eric Ortlund, Raymond Schinazi, Alexander Greninger, Mia Cirrincione, Dale Gort, Emily Kennedy, Adam Samuta, Megan Shaw, Brian Walsh, Eric Lai
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 2, Pp 286-290 (2021)
Goal: Monitoring the genetic diversity and emerging mutations of SARS-CoV-2 is crucial for understanding the evolution of the virus and assuring the performance of diagnostic tests, vaccines, and therapies against COVID-19. SARS-CoV-2 is still adapti
Externí odkaz:
https://doaj.org/article/02ba3987acda41658b1292e501fb96ab
Autor:
Mehul S. Suthar, Matthew G. Zimmerman, Robert C. Kauffman, Grace Mantus, Susanne L. Linderman, William H. Hudson, Abigail Vanderheiden, Lindsay Nyhoff, Carl W. Davis, Oluwaseyi Adekunle, Maurizio Affer, Melanie Sherman, Stacian Reynolds, Hans P. Verkerke, David N. Alter, Jeannette Guarner, Janetta Bryksin, Michael C. Horwath, Connie M. Arthur, Natia Saakadze, Geoffrey H. Smith, Srilatha Edupuganti, Erin M. Scherer, Kieffer Hellmeister, Andrew Cheng, Juliet A. Morales, Andrew S. Neish, Sean R. Stowell, Filipp Frank, Eric Ortlund, Evan J. Anderson, Vineet D. Menachery, Nadine Rouphael, Aneesh K. Mehta, David S. Stephens, Rafi Ahmed, John D. Roback, Jens Wrammert
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 3, Pp 100040- (2020)
Summary: SARS-CoV-2, the virus responsible for COVID-19, is causing a devastating worldwide pandemic, and there is a pressing need to understand the development, specificity, and neutralizing potency of humoral immune responses during acute infection
Externí odkaz:
https://doaj.org/article/5f530d0f4bbd408ebb78b8346f2ddc5f
Autor:
Eric Ortlund
Publikováno v:
Journal of Hebrew Scriptures, Vol 12 (2012)
Externí odkaz:
https://doaj.org/article/1635143711284aaba1927fdd35f6ce4b
Autor:
Xu Xu, Yue Li, Mahnoor Baqai, Pinyu Liao, Matthew Tillman, Eric Ortlund, David Cohen, Susan Hagen
Publikováno v:
Physiology. 38
Thioesterase superfamily member 1 (Them1) is a long-chain fatty acyl-CoA thioesterase that is highly expressed in brown adipose tissue (BAT), where it limits energy expenditure. Them1 is comprised of tandem enzymatic domains and a C-terminal lipid-bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8677f96e682cd6ba0b8d8e4e6e1c6a22
https://doi.org/10.1152/physiol.2023.38.s1.5731856
https://doi.org/10.1152/physiol.2023.38.s1.5731856
Autor:
Christopher S. Krumm, Renee S. Landzberg, Lavoisier Ramos-Espiritu, Carolina Adura, Xu Liu, Mariana Acuna, Yang Xie, Xu Xu, Matthew C. Tillman, Yingxia Li, J. Fraser Glickman, Eric Ortlund, John D. Ginn, David E. Cohen
Thioesterase superfamily member 1 (Them1; synonyms Acyl-CoA thioesterase 11 (Acot11) and steroidogenic acute regulatory protein-related lipid transfer (START) domain 14 (StarD14) is a long chain acyl-CoA thioesterase comprising two N-terminal hot-dog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54729709ca6c0a06c32c9d799f040f37
https://doi.org/10.1101/2022.10.15.512369
https://doi.org/10.1101/2022.10.15.512369
Autor:
Sanjeev Kumar, Anamika Patel, Lilin Lai, Chennareddy Chakravarthy, Rajesh Valanparambil, Elluri Seetharami Reddy, Kamalvishnu Gottimukkala, Meredith E. Davis-Gardner, Venkata Viswanadh Edara, Susanne Linderman, Kaustuv Nayak, Kritika Dixit, Pragati Sharma, Prashant Bajpai, Vanshika Singh, Filipp Frank, Narayanaiah Cheedarla, Hans P. Verkerke, Andrew S. Neish, John D. Roback, Grace Mantus, Pawan Kumar Goel, Manju Rahi, Carl W. Davis, Jens Wrammert, Sucheta Godbole, Amy R. Henry, Daniel C. Douek, Mehul S. Suthar, Rafi Ahmed, Eric Ortlund, Amit Sharma, Kaja Murali-Krishna, Anmol Chandele
Publikováno v:
Science advances. 8(40)
In this study, by characterizing several human monoclonal antibodies (mAbs) isolated from single B cells of the COVID-19–recovered individuals in India who experienced ancestral Wuhan strain (WA.1) of SARS-CoV-2 during early stages of the pandemic,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a33893ff2aaeb76ba3fbd27ec35021
https://pubmed.ncbi.nlm.nih.gov/36197988
https://pubmed.ncbi.nlm.nih.gov/36197988
Publikováno v:
Journal of the Endocrine Society. 6:A734-A735
Duchenne muscular dystrophy is a genetic disorder that shows chronic and progressive damage to skeletal and cardiac muscle leading to premature death. Anti-inflammatory corticosteroids targeting the glucocorticoid receptor (GR) are the current standa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91781e20d21c8b77cfd857e18f5d99ec
https://doi.org/10.1210/jendso/bvac150.1516
https://doi.org/10.1210/jendso/bvac150.1516
Autor:
Sanjeev Kumar, Anamika Patel, Lilin Lai, Chennareddy Chakravarthy, Rajesh Valanparambil, Meredith E. Davis-Gardner, Venkata Viswanadh Edara, Susanne Linderman, Elluri Seetharami Reddy, Kamalvishnu Gottimukkala, Kaustuv Nayak, Prashant Bajpai, Vanshika Singh, Filipp Frank, Narayanaiah Cheedarla, Hans P. Verkerke, Andrew S. Neish, John D. Roback, Grace Mantus, Pawan Kumar Goel, Manju Rahi, Carl W. Davis, Jens Wrammert, Mehul S. Suthar, Rafi Ahmed, Eric Ortlund, Amit Sharma, Kaja Murali-Krishna, Anmol Chandele
The SARS-CoV-2 BA.1 and BA.2 (Omicron) variants contain more than 30 mutations within the spike protein and evade therapeutic monoclonal antibodies (mAbs). Here, we report a receptor-binding domain (RBD) targeting human antibody (002-S21F2) that effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::144df164fe651bd371a0619d08cabe7c
https://doi.org/10.1101/2022.05.13.491770
https://doi.org/10.1101/2022.05.13.491770
Autor:
Sarah Farmer, Victoria Razin, Amanda Foster Peagler, Samantha Strickler, W. Bradley Fain, Gregory L. Damhorst, Russell R. Kempker, Nira R. Pollock, Oliver Brand, Brooke Seitter, Stacy S. Heilman, Eric J. Nehl, Joshua M. Levy, David S. Gottfried, Greg S. Martin, Morgan Greenleaf, David N. Ku, Jesse J. Waggoner, Elizabeth Iffrig, Robert G. Mannino, Yun F. Wang, Eric Ortlund, Julie Sullivan, Paulina A. Rebolledo, Viviana Clavería, John D. Roback, MacArthur Benoit, Cheryl Stone, Annette Esper, Filipp Frank, Wilbur A. Lam
Publikováno v:
Cell reports methods. 2(5)
During the COVID-19 pandemic, the development of point-of-care (POC) diagnostic testing accelerated in an unparalleled fashion. As a result, there has been an increased need for accurate, robust, and easy-to-use POC testing in a variety of non-tradit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8184889d06584a82898c171e288b8d61
https://pubmed.ncbi.nlm.nih.gov/35527805
https://pubmed.ncbi.nlm.nih.gov/35527805