Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Eric O Neill"'
Autor:
Simei Go, Constantinos Demetriou, Giampiero Valenzano, Sophie Hughes, Simone Lanfredini, Helen Ferry, Edward Arbe-Barnes, Shivan Sivakumar, Rachel Bashford-Rogers, Mark R Middleton, Somnath Mukherjee, Jennifer Morton, Keaton Jones, Eric O Neill
Publikováno v:
eLife, Vol 13 (2024)
The immunosuppressive microenvironment in pancreatic ductal adenocarcinoma (PDAC) prevents tumor control and strategies to restore anti-cancer immunity (i.e. by increasing CD8 T-cell activity) have had limited success. Here, we demonstrate how induci
Externí odkaz:
https://doaj.org/article/71c5b8de40e04161b42d0234f53620ea
Autor:
Milad Ghomlaghi, Mandy Theocharous, Nhan Hoang, Sung-Young Shin, Alex von Kriegsheim, Eric O’ Neill, Tao Zhang, Lan K. Nguyen
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109031- (2024)
Summary: The transcriptional co-activator YAP forms complexes with distinct transcription factors, controlling cell fate decisions, such as proliferation and apoptosis. However, the mechanisms underlying its context-dependent function are poorly defi
Externí odkaz:
https://doaj.org/article/ac43d1e023b14adeb764bd7c42e1ff0f
The Hippo pathway is an evolutionarily conserved signaling network that integrates diverse cues to regulate cell fate and organ homeostasis. The central downstream pathway protein is the transcriptional co-activator Yes-associated protein (YAP). Alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bca6aa77a925e21dcfa6de604aa2d996
https://doi.org/10.1101/2022.04.06.487403
https://doi.org/10.1101/2022.04.06.487403
Autor:
Eric O’ Neill, Daniela Pankova, Anna M. Grawenda, Nikola Vlahov, Aswin George Abraham, Dafni-Eleftheria Pefani, Simon Scrace
Publikováno v:
Molecular Cell. 63:156-166
Epigenetic inactivation of the Hippo pathway scaffold RASSF1A is associated with poor prognosis in a wide range of sporadic human cancers. Loss of expression reduces tumor suppressor activity and promotes genomic instability, but how this pleiotropic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8643e74217226021360c23b3e458e4b0
https://doi.org/10.1016/j.molcel.2016.05.012
https://doi.org/10.1016/j.molcel.2016.05.012
Autor:
Eric O Neill, Falih Ahmad
Publikováno v:
NEW DEVELOPMENTS IN ENGINEERING, SCIENCE AND TECHNOLOGY.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd9978e82fafad1328163b2c8d82c6d0
https://doi.org/10.23953/cloud.iestoc.371
https://doi.org/10.23953/cloud.iestoc.371