Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Eric O Johnson"'
Autor:
Shelina Ramnarine, Juan Zhang, Li-Shiun Chen, Robert Culverhouse, Weimin Duan, Dana B Hancock, Sarah M Hartz, Eric O Johnson, Emily Olfson, Tae-Hwi Schwantes-An, Nancy L Saccone
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0137601 (2015)
Imputation, the process of inferring genotypes for untyped variants, is used to identify and refine genetic association findings. Inaccuracies in imputed data can distort the observed association between variants and a disease. Many statistics are us
Externí odkaz:
https://doaj.org/article/fa9d70bf91824be19cdcd81f1aacc7dc
Autor:
Eric O Johnson, Dana B Hancock, Nathan C Gaddis, Joshua L Levy, Grier Page, Scott P Novak, Cristie Glasheen, Nancy L Saccone, John P Rice, Michael P Moreau, Kimberly F Doheny, Jane M Romm, Andrew I Brooks, Bradley E Aouizerat, Laura J Bierut, Alex H Kral
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118149 (2015)
Fifty percent of variability in HIV-1 susceptibility is attributable to host genetics. Thus identifying genetic associations is essential to understanding pathogenesis of HIV-1 and important for targeting drug development. To date, however, CCR5 rema
Externí odkaz:
https://doaj.org/article/fd28aa1c0fea4988aacabbe825e692bb
Autor:
Eric O Johnson, Dana B Hancock, Nathan C Gaddis, Joshua L Levy, Grier Page, Scott P Novak, Cristie Glasheen, Nancy L Saccone, John P Rice, Michael P Moreau, Kimberly F Doheny, Jane M Romm, Andrew I Brooks, Alex H Kral
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0129671 (2015)
Externí odkaz:
https://doaj.org/article/febf30308ac74183af2838b4450f13c2
Autor:
Dana B Hancock, Joshua L Levy, Nathan C Gaddis, Laura J Bierut, Nancy L Saccone, Grier P Page, Eric O Johnson
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50610 (2012)
Genotype imputation, used in genome-wide association studies to expand coverage of single nucleotide polymorphisms (SNPs), has performed poorly in African Americans compared to less admixed populations. Overall, imputation has typically relied on Hap
Externí odkaz:
https://doaj.org/article/79425285b59c4a3eb373e4c3a187f24e
Autor:
Amy Moore, Jesse A. Marks, Bryan C. Quach, Yuelong Guo, Laura J. Bierut, Nathan C. Gaddis, Dana B. Hancock, Grier P. Page, Eric O. Johnson
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Where sufficiently large genome-wide association study (GWAS) samples are not currently available or feasible, methods that leverage increasing knowledge of the biological function of variants may illuminate discoveries without increasing sa
Externí odkaz:
https://doaj.org/article/94b3cb58479548ce83e501a5b657bb9f
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Cocaine use (CU) is associated with psychiatric and medical diseases. Little is known about the mechanisms of CU-related comorbidities. Findings from preclinical and clinical studies have suggested that CU is associated with aberr
Externí odkaz:
https://doaj.org/article/267ee5fed7384dd1a73438d967bdead0
Autor:
Eric O. Johnson
Many librarians'job responsibilities increasingly require them to understand and handle data. Learn how to be an effective data librarian—even if you never expected to need data skills.The field of data librarianship is rapidly growing, and some li
Publikováno v:
Environment International, Vol 177, Iss , Pp 107987- (2023)
Background: Air pollution exposure is associated with cardiovascular morbidity and mortality. Although exposure to air pollution early in life may represent a critical window for development of cardiovascular disease risk factors, few studies have ex
Externí odkaz:
https://doaj.org/article/1ce0b6bbd15e47d18546cb5c3fad1550
Autor:
Chang Shu, Amy C. Justice, Xinyu Zhang, Vincent C. Marconi, Dana B. Hancock, Eric O. Johnson, Ke Xu
Publikováno v:
Epigenetics, Vol 16, Iss 7, Pp 741-753 (2021)
Background: With the improved life expectancy of people living with HIV (PLWH), identifying vulnerable subpopulations at high mortality risk is important. Evidences showed that DNA methylation (DNAm) is associated with mortality in non-HIV population
Externí odkaz:
https://doaj.org/article/899324e66ef049239af733e8474cb2f1
Autor:
Bryan C. Quach, Michael J. Bray, Nathan C. Gaddis, Mengzhen Liu, Teemu Palviainen, Camelia C. Minica, Stephanie Zellers, Richard Sherva, Fazil Aliev, Michael Nothnagel, Kendra A. Young, Jesse A. Marks, Hannah Young, Megan U. Carnes, Yuelong Guo, Alex Waldrop, Nancy Y. A. Sey, Maria T. Landi, Daniel W. McNeil, Dmitriy Drichel, Lindsay A. Farrer, Christina A. Markunas, Jacqueline M. Vink, Jouke-Jan Hottenga, William G. Iacono, Henry R. Kranzler, Nancy L. Saccone, Michael C. Neale, Pamela Madden, Marcella Rietschel, Mary L. Marazita, Matthew McGue, Hyejung Won, Georg Winterer, Richard Grucza, Danielle M. Dick, Joel Gelernter, Neil E. Caporaso, Timothy B. Baker, Dorret I. Boomsma, Jaakko Kaprio, John E. Hokanson, Scott Vrieze, Laura J. Bierut, Eric O. Johnson, Dana B. Hancock
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
There is strong genetic evidence for cigarette smoking behaviors, yet little is known on nicotine dependence (ND). Here, the authors perform a genome-wide association study on ND in 58,000 smokers, identifying five genome-wide significant loci.
Externí odkaz:
https://doaj.org/article/508c732e509b4270b0f67aeb1af54d38