Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Eric Nilsson"'
Autor:
Martin Kaefer, Richard Rink, Rosalia Misseri, Paul Winchester, Cathy Proctor, Millissia Ben Maamar, Daniel Beck, Eric Nilsson, Michael K. Skinner
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Abnormal penile foreskin development in hypospadias is the most frequent genital malformation in male children, which has increased dramatically in recent decades. A number of environmental factors have been shown to be associated with hypos
Externí odkaz:
https://doaj.org/article/86b6eea92e424701a70d61e8b8e07259
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Preterm birth is the major cause of newborn and infant mortality affecting nearly one in every ten live births. The current study was designed to develop an epigenetic biomarker for susceptibility of preterm birth using buccal cells from the
Externí odkaz:
https://doaj.org/article/b5c1f1fdde7d483a802a35aa7544c9df
Autor:
Ryan P. Thompson, Daniel Beck, Eric Nilsson, Millissia Ben Maamar, Margarett Shnorhavorian, Michael K. Skinner
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105570- (2022)
Summary: The current study was designed to use a rodent model to determine if exposure to the chemotherapy drug ifosfamide during puberty can induce altered phenotypes and disease in the grand-offspring of exposed individuals through epigenetic trans
Externí odkaz:
https://doaj.org/article/26699f6cbf8044b8a9796984ca8d0c9b
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103786- (2022)
Summary: Because epigenetics is a critical component for gene expression, the hypothesis was tested that DNA methylation alterations are dynamic and continually change throughout gametogenesis to generate the mature sperm. Developmental alterations a
Externí odkaz:
https://doaj.org/article/8c054ffaec344a73985f55044cb35b6d
Autor:
Michael K. Skinner, Eric Nilsson, Ingrid Sadler-Riggleman, Daniel Beck, Millissia Ben Maamar, John R. McCarrey
Publikováno v:
Epigenetics, Vol 14, Iss 7, Pp 721-739 (2019)
A number of environmental factors from nutrition to toxicants have been shown to promote the epigenetic transgenerational inheritance of disease and phenotypic variation. This requires alterations in the germline (sperm or egg) epigenome. Previously,
Externí odkaz:
https://doaj.org/article/53e6b19b07454df5943332ba78dbf9c1
Publikováno v:
Adipocyte, Vol 8, Iss 1, Pp 362-378 (2019)
The incidence of obesity has increased dramatically over the past two decades with a prevalence of approximately 40% of the adult population within the United States. The current study examines the potential for transgenerational adipocyte (fat cell)
Externí odkaz:
https://doaj.org/article/7aa7ff87a08f486c820d9d2dd19bfe07
Autor:
Eric Nilsson, Rachel Klukovich, Ingrid Sadler-Riggleman, Daniel Beck, Yeming Xie, Wei Yan, Michael K. Skinner
Publikováno v:
Epigenetics, Vol 13, Iss 8, Pp 875-895 (2018)
Two of the most prevalent ovarian diseases affecting women’s fertility and health are Primary Ovarian Insufficiency (POI) and Polycystic Ovarian Syndrome (PCOS). Previous studies have shown that exposure to a number of environmental toxicants can p
Externí odkaz:
https://doaj.org/article/17bb9614104b47a2b2ed74364f4c48c0
Autor:
Michael K. Skinner, Millissia Ben Maamar, Ingrid Sadler-Riggleman, Daniel Beck, Eric Nilsson, Margaux McBirney, Rachel Klukovich, Yeming Xie, Chong Tang, Wei Yan
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-24 (2018)
Abstract Background Environmental toxicants such as DDT have been shown to induce the epigenetic transgenerational inheritance of disease (e.g., obesity) through the germline. The current study was designed to investigate the DDT-induced concurrent a
Externí odkaz:
https://doaj.org/article/558977bb942544f5ae4291863e380409
Autor:
Eric Nilsson, Stephanie E King, Margaux McBirney, Deepika Kubsad, Michelle Pappalardo, Daniel Beck, Ingrid Sadler-Riggleman, Michael K Skinner
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202662 (2018)
Exposure to vinclozolin has been shown to induce the epigenetic transgenerational inheritance of increased susceptibility to disease, and to induce transgenerational changes to the epigenome. In the current study, gestating F0 generation rats were ex
Externí odkaz:
https://doaj.org/article/f16dbae8e519481d9a9be907835f404d
Autor:
Margaux McBirney, Stephanie E King, Michelle Pappalardo, Elizabeth Houser, Margaret Unkefer, Eric Nilsson, Ingrid Sadler-Riggleman, Daniel Beck, Paul Winchester, Michael K Skinner
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184306 (2017)
Ancestral environmental exposures to a variety of environmental toxicants and other factors have been shown to promote the epigenetic transgenerational inheritance of adult onset disease. The current study examined the potential transgenerational act
Externí odkaz:
https://doaj.org/article/c41ec7e9d7a74d4da936a808fd9b8d9f