Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Eric N. Phillips"'
Autor:
Howard L. Liber, Eric N. Phillips
Publikováno v:
Critical Reviews in Eukaryotic Gene Expression. 8:257-276
Ionizing radiation induces cancer in humans, but the mechanisms are not established. One simple way by which radiation could induce cancer is by inducing a genetic mutation in one or more of the multiple steps in the oncogenic pathway. However, many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ff6ce518a48a95bb709b6136033eb9
https://doi.org/10.1615/critreveukargeneexpr.v8.i3-4.20
https://doi.org/10.1615/critreveukargeneexpr.v8.i3-4.20
Autor:
Jeffrey G. Supko, Jeffrey W. Clark, Moira Kirvan, Susan L. Connors, Thomas A. Puchalski, Barbara Rattner, Joann Proper, Rocio Garcia-Carbonero, C. Sidor, Joseph Paul Eder, Lowell E. Schnipper, Milos J. Janicek, William E. Fogler, David P. Ryan, Judah Folkman, Eric N. Phillips, Mary T. Keogan, Donald Kufe, Lawrence N. Shulman, Nancy M. Kinchla
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 20(18)
PURPOSE: To perform a phase I trial of recombinant human endostatin (rhEndostatin; EntreMed, Rockville, MD) given as a daily 20-minute intravenous (IV) injection in adult patients with refractory solid tumors. PATIENTS AND METHODS: The daily dose was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7909a9f813301cfedfb12f90df3400
https://pubmed.ncbi.nlm.nih.gov/12228194
https://pubmed.ncbi.nlm.nih.gov/12228194
Autor:
Thomas Helleday, Bradley D. Preston, Mark Meuth, Atul Mohindra, Eric N. Phillips, Laura E. Hays
Publikováno v:
Human molecular genetics. 11(18)
Loss of mismatch repair (MMR) leads to a complex mutator phenotype that appears to drive the development of a subset of colon cancers. Here we show that MMR-deficient tumour cell lines are highly sensitive to the toxic effects of thymidine relative t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac967211c5a4bd13c6dd8843c58aec7
https://pubmed.ncbi.nlm.nih.gov/12189171
https://pubmed.ncbi.nlm.nih.gov/12189171
Publikováno v:
Radiation Research. 147:138
Previous work with two closely related human lymphoblast cell lines demonstrated that WTK1 cells are more resistant than TK6 cells to X-ray-induced cytotoxicity, but more mutable at both the TK and HPRT loci. It was subsequently determined that WTK1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e54a376f9dca1b7dff2f15b3ca0a8402
https://doi.org/10.2307/3579414
https://doi.org/10.2307/3579414
Publikováno v:
Radiation Research. 143:255
Previous work showed that WTK1 human lymphoblastoid cells are radioresistant but more sensitive to X-ray-induced mutation than the closely related line TK6. In addition, WTK1 cells contain a mutant p53 while in TK6 cells p53 is wild-type. In this wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::606a6b133abc6f8239eef5fa17eeadff
https://doi.org/10.2307/3579211
https://doi.org/10.2307/3579211