Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Eric N. Jiménez-Vázquez"'
Autor:
Rodrigo Aguayo-Ortiz, Jeffery Creech, Eric N. Jiménez-Vázquez, Guadalupe Guerrero-Serna, Nulang Wang, Andre Monteiro da Rocha, Todd J. Herron, L. Michel Espinoza-Fonseca
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Membrane proteins constitute a substantial fraction of the human proteome, thus representing a vast source of therapeutic drug targets. Indeed, newly devised technologies now allow targeting “undruggable” regions of membrane proteins to
Externí odkaz:
https://doaj.org/article/39ac1d8d1b97427ba94cce0ca3901e15
Publikováno v:
Biophysical Journal. 122:379a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24d5a42b431b6d600cfbe87f9df6e455
https://doi.org/10.1016/j.bpj.2022.11.2083
https://doi.org/10.1016/j.bpj.2022.11.2083
Autor:
Guadalupe Guerrero-Serna, Jeffery Creech, Nulang Wang, Andre Monteiro da Rocha, L. Michel Espinoza-Fonseca, Rodrigo Aguayo-Ortiz, Todd J. Herron, Eric N. Jiménez-Vázquez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Membrane proteins constitute a substantial fraction of the human proteome, thus representing a vast source of therapeutic drug targets. Indeed, newly devised technologies now allow targeting “undruggable” regions of membrane proteins to modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d728ece1c8146af4fa60040be5a86054
https://doi.org/10.1038/s41598-021-96217-7
https://doi.org/10.1038/s41598-021-96217-7
Autor:
Eric N. Jiménez-Vázquez, Jeffery Creech, Rodrigo Aguayo-Ortiz, Guadalupe Guerrero-Serna, L. M. Espinoza-Fonseca, Todd J. Herron, Monteiro da Rocha A, Nulang Wang
Membrane proteins constitute a substantial fraction of the human proteome, thus representing a vast source of therapeutic drug targets. Indeed, newly devised technologies now allow targeting “undruggable” regions of membrane proteins to modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fa0fa9f8cfeaae9f52693f44d4054cd
https://doi.org/10.1101/2021.03.19.432117
https://doi.org/10.1101/2021.03.19.432117
Autor:
Daniela Ponce-Balbuena, Jeffery Creech, Eric N. Jiménez-Vázquez, Travis J. Block, Sy Griffey, Todd J. Herron, Andre Monteiro da Rocha, Milos Marinkovic
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
The immature phenotype of human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) is a major limitation to the use of these valuable cells for pre-clinical toxicity testing and for disease modeling. Here we tested the hypothesis that h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::637925a1d6936faf656e60d4f31e72e6
https://doi.org/10.1038/s41598-020-76052-y
https://doi.org/10.1038/s41598-020-76052-y
Autor:
Eva Delpón, Rafael J. Ramirez, Marcos Matamoros, Todd J. Herron, Daniela Ponce-Balbuena, Kuljeet Kaur, Héctor H. Valdivia, Manuel Zarzoso, Francisco J. Alvarado, B. Cicero Willis, Eric N. Jiménez-Vázquez, F. Javier Díez-Guerra, José Jalife, Ricardo Caballero, Carmen R. Valdivia, Andre Monteiro da Rocha, Guadalupe Guerrero-Serna, Marta Pérez-Hernández, Katherine Campbell
Publikováno v:
Circulation Research. 122:1501-1516
Rationale: In cardiomyocytes, Na V 1.5 and Kir2.1 channels interact dynamically as part of membrane bound macromolecular complexes. Objective: The objective of this study was to test whether Na V 1.5 and Kir2.1 preassemble during early forward traffi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07fd35e4da98c731c299754534847197
https://doi.org/10.1161/circresaha.117.311872
https://doi.org/10.1161/circresaha.117.311872
Autor:
Eric N. Jiménez-Vázquez, David K. Jones, Chiamaka U. Ukachukwu, Andre Monteiro da Rocha, Abhilasha Jain
Publikováno v:
Biophysical Journal. 120:243a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f396fa10acd2e19527d39d59d66ec853
https://doi.org/10.1016/j.bpj.2020.11.1593
https://doi.org/10.1016/j.bpj.2020.11.1593
Autor:
Eric N. Jiménez-Vázquez
Publikováno v:
Biophysical Journal. 118:418a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12df7138938cb6af16715ee0274ffe0e
https://doi.org/10.1016/j.bpj.2019.11.2361
https://doi.org/10.1016/j.bpj.2019.11.2361
Autor:
Paloma Nieto-Marín, David Tinaquero, Marcos Matamoros, Raquel G. Utrilla, Marta Pérez-Hernández, Silvia Alfayate, José Jalife, Katherine Campbell, Teresa Crespo, Daniela Ponce-Balbuena, F. Javier Díez-Guerra, Eva Delpón, Ricardo Caballero, Andre Monteiro da Rocha, B. Cicero Willis, Juan Tamargo, Eric N. Jiménez-Vázquez, Todd J. Herron, Raquel de Andrés, Guadalupe Guerrero-Serna
Publikováno v:
JCI Insight. 3
Cardiac Nav1.5 and Kir2.1-2.3 channels generate Na (INa) and inward rectifier K (IK1) currents, respectively. The functional INa and IK1 interplay is reinforced by the positive and reciprocal modulation between Nav15 and Kir2.1/2.2 channels to streng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1bf7d4e53cc16e099494b339798458
https://doi.org/10.1172/jci.insight.96291
https://doi.org/10.1172/jci.insight.96291
Autor:
Ubaldo García, Eric N. Jiménez-Vázquez, Rosa María Uribe, Clara Díaz-Velásquez, Juan M. Arias
Publikováno v:
Journal of Neuroscience Research. 94:190-203
Molecular cloning has introduced an unexpected, large diversity of neurotransmitter hetero- oligomeric receptors. Extensive research on the molecular structure of the γ-aminobutyric acid receptor (GABAR) has been of great significance for understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2670ad17c5662924b0aec909706674db
https://doi.org/10.1002/jnr.23695
https://doi.org/10.1002/jnr.23695