Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eric N. Hampton"'
Autor:
Leopold Garnar-Wortzel, Timothy R. Bishop, Seiya Kitamura, Natalia Milosevich, Joshua N. Asiaban, Xiaoyu Zhang, Qinheng Zheng, Emily Chen, Anissa R. Ramos, Christopher J. Ackerman, Eric N. Hampton, Arnab K. Chatterjee, Travis S. Young, Mitchell V. Hull, K. Barry Sharpless, Benjamin F. Cravatt, Dennis W. Wolan, Michael A. Erb
Publikováno v:
ACS Central Science, Vol 7, Iss 5, Pp 815-830 (2021)
Externí odkaz:
https://doaj.org/article/097fa2b7ad3f4a1fa4c7766ad3a5dcd3
Autor:
Eduardo Laborda, Magdalena Mazagova, Sida Shao, Xinxin Wang, Herlinda Quirino, Ashley K. Woods, Eric N. Hampton, David T. Rodgers, Chan Hyuk Kim, Peter G. Schultz, Travis S. Young
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2259 (2017)
The treatment of patients with acute myeloid leukemia (AML) with targeted immunotherapy is challenged by the heterogeneity of the disease and a lack of tumor-exclusive antigens. Conventional immunotherapy targets for AML such as CD33 and CD123 have b
Externí odkaz:
https://doaj.org/article/aae329c0600144cf802d66b029d2bed5
Autor:
Flavian Thelen, Joseph M McGraw, Deborah A. Witherden, Wendy L. Havran, Nelson E Bruno, Eric N. Hampton, Travis S. Young
Publikováno v:
Journal of Experimental Medicine. 218
T cells are critical mediators of antitumor immunity and a major target for cancer immunotherapy. Antibody blockade of inhibitory receptors such as PD-1 can partially restore the activity of tumor-infiltrating lymphocytes (TILs). However, the activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79bdc9d8f1cff59b3f3eaec8982e0ce2
https://doi.org/10.1084/jem.20202644
https://doi.org/10.1084/jem.20202644
Autor:
Christina Jamieson, Sung Chang Lee, Jennifer Ma, Sean B. Joseph, Minsoo Kim, Anna A. Kulidjian, Peter G. Schultz, Ashley K. Woods, Wenxue Ma, Mike Petrassi, Michelle Muldong, Travis S. Young, Hwayoung Yun, Christopher J. Kane, Eric N. Hampton, Chan Hyuk Kim, Jing Li, Vanessa Núñez, Eduardo Laborda, Klyushnichenko Vadim, Sei-hyun Choi, John Wisler, Christina C. N. Wu
Publikováno v:
Science Advances
Science advances, vol 7, iss 33
Science advances, vol 7, iss 33
CCW702 is a bispecific antibody that combines the specificity of an imaging ligand with the potency of a T cell immunotherapy.
Despite the development of next-generation antiandrogens, metastatic castration-resistant prostate cancer (mCRPC) rema
Despite the development of next-generation antiandrogens, metastatic castration-resistant prostate cancer (mCRPC) rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f980a0dc297d3c689185170e7863bb3
https://pubmed.ncbi.nlm.nih.gov/34380625
https://pubmed.ncbi.nlm.nih.gov/34380625
Autor:
Benjamin F. Cravatt, Qinheng Zheng, Leopold Garnar-Wortzel, Eric N. Hampton, Seiya Kitamura, Anissa R. Ramos, Michael A. Erb, Joshua N. Asiaban, Natalia Milosevich, K. Barry Sharpless, Xiaoyu Zhang, Emily Chen, Travis S. Young, Timothy R. Bishop, Arnab K. Chatterjee, Christopher J. Ackerman, Dennis W. Wolan, Mitchell V. Hull
Transcriptional co-regulators, which mediate chromatin-dependent transcriptional signaling, represent tractable targets to modulate tumorigenic gene expression programs with small molecules. Genetic loss-of-function studies have recently implicated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5d4cf4198bd8dc8c44f5702413eca61
https://doi.org/10.1101/2020.12.01.406694
https://doi.org/10.1101/2020.12.01.406694
Autor:
Justin Wang, Michael A. Erb, Timothy R. Bishop, Natalia Milosevich, Yuxiang Zhang, Travis S. Young, Christopher J Ackerman, Eric N Hampton, Joshua N Asiaban, Emily Chen, Mitchell V. Hull, Benjamin F. Cravatt
Publikováno v:
ACS Chem Biol
ENL is a transcriptional co-activator that recruits elongation machinery to active cis-regulatory elements upon binding of its YEATS domain – a chromatin reader module – to acylated lysine side chains. Discovery chemistry for the ENL YEATS domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48bf4d3fcd795b9e59e3bcca5e0dc75e
https://pubmed.ncbi.nlm.nih.gov/32176478
https://pubmed.ncbi.nlm.nih.gov/32176478
Autor:
Yu Cao, David T. Rodgers, Juanjuan Du, Insha Ahmad, Eric N. Hampton, Jennifer S. Y. Ma, Magdalena Mazagova, Sei-hyun Choi, Hwa Young Yun, Han Xiao, Pengyu Yang, Xiaozhou Luo, Reyna K. V. Lim, Holly M. Pugh, Feng Wang, Stephanie A. Kazane, Timothy M. Wright, Chan Hyuk Kim, Peter G. Schultz, Travis S. Young
Publikováno v:
Angewandte Chemie. 128:7646-7650
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65790a33663b64df455a3bc791b7f74f
https://doi.org/10.1002/ange.201601902
https://doi.org/10.1002/ange.201601902
Autor:
Elvira Khialeeva, Lance Sherwood, Ian R. Hardy, Jennifer Ma, Meredith Weglarz, Christopher J. Ackerman, Sung Chang Lee, Sophie Viaud, Brent Benish, Travis S. Young, Eric N. Hampton, Ashley K. Woods, Vanessa Núñez
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Chimeric antigen receptor (CAR) T cell therapy represents a powerful strategy in immuno-oncology. Nevertheless, associated life-threatening toxicities and chronic B cell aplasia have underscored the need to control engineered T cells in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bbd9a506d99490d2ef1da7252fe0e8b
https://doi.org/10.1073/pnas.1810060115
https://doi.org/10.1073/pnas.1810060115
Autor:
Jun Li, Christine Tumanut, Julie-Ann Gavigan, Waan-Jeng Huang, Eric N. Hampton, Rachelle Tumanut, Ka Fai Suen, John W. Trauger, Glen Spraggon, Scott A. Lesley, Gene Liau, David Yowe, Jennifer L. Harris
Publikováno v:
Biochemical Journal; 2007, Vol. 406 Issue 2, p203-207, 5p