Výsledky vyhledávání - "Eric Mickelson"

Collection and processing of whole blood for transformation of peripheral blood mononuclear cells and extraction of DNA: the Type 1 Diabetes Genetics Consortium

Autor: Gary J. Olsem, Sarah Nutland, June J Pierce, Ian Nicholson, Michael W. Steffes, Joan E. Hilner, Letitia H Perdue, Michael D. Varney, Beena Akolkar, Silke Rosinger, John A. Hansen, Bernard O Boehm, T Dgc, Eric Mickelson, Concepcion Nierras

Publikováno v: Clinical Trials (London, England)

Background and Purpose To yield large amounts of DNA for many genotype analyses and to provide a renewable source of DNA, the Type 1 Diabetes Genetics Consortium (T1DGC) harvested DNA and peripheral blood mononuclear cells (PBMCs) from individuals wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece286f10e91ddf4413ce2bd8c4057df
https://doi.org/10.1177/1740774510373493

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Limits of HLA mismatching in unrelated hematopoietic cell transplantation

Autor: Ted Gooley, Mari Malkki, Claudio Anasetti, Anajane G. Smith, Paul J. Martin, Effie W. Petersdorf, John A. Hansen, Eric Mickelson, Ann E. Woolfrey, Jerald P. Radich

Publikováno v: Blood. 104:2976-2980

HLA matching between the donor and recipient improves the success of unrelated hematopoietic cell transplantation (HCT). Matched donors are available for only a minority of patients. Further information is needed to evaluate the limits of HLA mismatc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52a937d73d0a19979164feef9a85a705
https://doi.org/10.1182/blood-2004-04-1674

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Killer Ig-Like Receptor Haplotype Analysis by Gene Content: Evidence for Genomic Diversity with a Minimum of Six Basic Framework Haplotypes, Each with Multiple Subsets

Autor: Katharine C. Hsu, Eric Mickelson, Annamalai Selvakumar, Richard J. O’Reilly, Bo Dupont, Xiao-Rong Liu

Publikováno v: The Journal of Immunology. 169:5118-5129

Killer Ig-like receptor (KIR) genes constitute a multigene family whose genomic diversity is achieved through differences in gene content and allelic polymorphism. KIR haplotypes containing a single activating KIR gene (A-haplotypes), and KIR haploty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2185208197793b1e59fca5815d7af070
https://doi.org/10.4049/jimmunol.169.9.5118

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The biological significance of HLA-DP gene variation in haematopoietic cell transplantation

Autor: T. E. D. Gooley, Ann E. Woolfrey, John A. Hansen, Eric Mickelson, Claudio Anasetti, Anajane G. Smith, Paul J. Martin, Mari Malkki, Effie W. Petersdorf

Publikováno v: British Journal of Haematology. 112:988-994

Although it has been over 25 years since HLA-DP was mapped to the major histocompatibility complex (MHC), its biological functions remain ill-defined. We sought to test the hypothesis that HLA-DP functions in a manner similar to that of other class I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e5f6498f4053c49b211abf109c679e2c
https://doi.org/10.1046/j.1365-2141.2001.02655.x

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Effect of HLA mismatches on the outcome of hematopoietic transplants

Autor: John A. Hansen, Ann E. Woolfrey, Paul J. Martin, Effie W. Petersdorf, Claudio Anasetti, Eric Mickelson

Publikováno v: Current Opinion in Immunology. 11:521-526

Hematopoietic cell transplantation from unrelated volunteer donors for the treatment of hematological malignancy can be optimized by complete and precise matching for HLA class I and II alleles between the donor and recipient. Survival is improved wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d96dd216b68345c128cf1151a2b1e218
https://doi.org/10.1016/s0952-7915(99)00016-3

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Optimizing Outcome After Unrelated Marrow Transplantation by Comprehensive Matching of HLA Class I and II Alleles in the Donor and Recipient

Autor: John A. Hansen, Paul J. Martin, Ann E. Woolfrey, Effie W. Petersdorf, Claudio Anasetti, Ted Gooley, Eric Mickelson, Anajane G. Smith

Publikováno v: Blood. 92:3515-3520

In unrelated marrow transplantation, the benefit of matching class II HLA-DRB1 and DQB1 alleles of the donor and recipient is well documented. Little is known about the clinical relevance of matching for class I HLA-A, B, and C alleles. We used DNA-a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f01823f3c2dd1ab159f109a704218b7
https://doi.org/10.1182/blood.v92.10.3515

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A Comparative Study of HLA-DRB Typing by Transcription-Mediated Amplification with the Hybridization Protection Assay (TMA/HPA) versus PCR/SSOP

Autor: John A. Hansen, Koichi sMatsubara, Eric Mickelson, L. A. Guthrie, Lois Regen, Ahmad Marashi, Anajane G. Smith

Publikováno v: Human Immunology. 55:74-84

To evaluate alternative human leukocyte antigen (HLA)-DNA typing methods, we used a system of transcription-mediated amplification (TMA) with a probe hybridization protection assay (HPA) in a microtiter plate format developed by Chugai Pharmaceutics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0c9321b5bf26bc5daf8687aa37ae6c
https://doi.org/10.1016/s0198-8859(97)00085-2

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Association of HLA-C Disparity With Graft Failure After Marrow Transplantation From Unrelated Donors

Autor: Susan K. McKinney, Eric Mickelson, Anajane G. Smith, Claudio Anasetti, Paul J. Martin, Gary Longton, John A. Hansen, Effie W. Petersdorf

Publikováno v: Blood. 89:1818-1823

Disparity for HLA-A or HLA-B antigens increases the risk of marrow graft rejection, but the relevance of HLA-C is unknown because typing methods have not been sufficiently accurate for clinical use. We designed a matched case-control study and employ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b74031788e63b3c6c2fac75c66641e
https://doi.org/10.1182/blood.v89.5.1818.1818_1818_1823

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Six new DR52-associated DRB1 alleles, three of DR8, two of DR11, and one of DR6, reflect a variety of mechanisms which generate polymorphism in the MHC

Autor: John A. Hansen, Eduardo Antônio Donadi, Anajane G. Smith, J. L. Nelson, L. A. Guthrie, Eric Mickelson, Lois Regen

Publikováno v: Tissue Antigens. 48:118-126

We have sequenced DNA from six new DR52-associated DRB1 alleles initially detected by PCR/SSOP analysis. Three DR8 associated alleles differed from previously known alleles by single nucleotide substitutions. DRB1*0807 and DRB1*0811 both vary from DR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc2f9c8be6be57aa7e748f256cd890f0
https://doi.org/10.1111/j.1399-0039.1996.tb02616.x

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The significance of HLA-DRB1 matching on clinical outcome after HLA-A, B, DR identical unrelated donor marrow transplantation

Autor: John A. Hansen, Claudio Anasetti, Anajane G. Smith, Gary Longton, Effie W. Petersdorf, Paul J. Martin, Eric Mickelson

Publikováno v: Blood. 86:1606-1613

Despite matching for serologically defined HLA-A, B, DR antigens, acute graft-versus-host disease (GVHD) is a major complication contributing to increased morbidity and mortality in patients who undergo marrow transplantation from unrelated donors. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4735d54f8805878e644efe124cecc022
https://doi.org/10.1182/blood.v86.4.1606.bloodjournal8641606

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