Serum Bovine Immunoglobulins Improve Inflammation and Gut Barrier Function in Persons with HIV and Enteropathy on Suppressive ART

Autor: Netanya Sandler Utay, Anoma Somasunderam, John E. Hinkle, Bryon W. Petschow, Christopher J. Detzel, Ma Somsouk, Carl J. Fichtenbaum, Eric M. Weaver, Audrey L. Shaw, David M. Asmuth

Publikováno v: Pathogens and Immunity, Vol 4, Iss 1, Pp 124-146 (2019)

Background: Systemic inflammation persists in chronic HIV infection and is associated with increased rates of non-AIDS events such as cardiovascular and liver disease. Increased gut permeability and systemic exposure to microbial products are key dri

Externí odkaz: https://doaj.org/article/2972d5d8fd3e4bb6b76478e0a00bec79

Absorption and safety of serum-derived bovine immunoglobulin/protein isolate in healthy adults

Autor: Gerald L. Klein, John Hinkle, David W Mathews, Timothy P Bradshaw, Bryon W. Petschow, Christopher J. Detzel, Eric M. Weaver, Audrey L. Shaw

Publikováno v: Clinical and Experimental Gastroenterology

Audrey L Shaw,1 David W Mathews,1 John E Hinkle,2 Bryon W Petschow,1 Eric M Weaver,3 Christopher J Detzel,1 Gerald L Klein,4 Timothy P Bradshaw1 1Clinical Development, Entera Health, Inc., 2Life Sciences Consulting and Analytics, EarlyPhase Sciences,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7967230e00ccd96a1d7444296b8b74
https://doi.org/10.2147/ceg.s120118

Comparison of the amino acid and peptide composition and postprandial response of beef, hydrolyzed chicken, and whey proteinnutritional preparations

Autor: Christopher J. Detzel, Bryon W. Petschow, Nicole Johnson, Eric M. Weaver

Publikováno v: Functional Foods in Health and Disease, Vol 6, Iss 10, Pp 612-626 (2016)

Background: Increasing dietary protein intake synergistically improves the effect of exercise to stimulate muscle protein synthesis. The purpose of this study was to evaluate the plasma amino acid response of two novel protein nutritional preparation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::7e2fbce48e5abc43cd3441f1e882f0a1
http://ffhdj.com/index.php/ffhd/article/view/308/537

Dietary intervention with serum-derived bovine immunoglobulins protects barrier function in a mouse model of colitis

Autor: Mònica Maijó, Joy M. Campbell, Javier Polo, Miquel Moretó, Louis E. Russell, Anna Pérez-Bosque, Joe D. Crenshaw, Lluïsa Miró, Eric M. Weaver

Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 308:G1012-G1018

Dietary supplementation with immunoglobulins from animal plasma has anti-inflammatory effects on intestinal and lung models of acute inflammation. Here, we aimed to establish whether dietary intervention with serum-derived bovine immunoglobulin (SBI)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6df9b386378126ca6d31cbc642c4f7
https://doi.org/10.1152/ajpgi.00378.2014

Evaluation of oral serum-derived bovine immunoglobulins in HIV-infected patients with chronic idiopathic diarrhea

Autor: Audrey L. Shaw, Carl J. Fichtenbaum, Bryon W. Petschow, Eric M. Weaver, Ma Somsouk, Netanya S. Utay, David M. Asmuth, Anthony LaMarca, John Hinkle, Christopher J. Detzel

Publikováno v: Asmuth, DM; Hinkle, JE; LaMarca, A; Fichtenbaum, CJ; Somsouk, M; Utay, NS; et al.(2017). Evaluation of oral serum-derived bovine immunoglobulins in HIV-infected patients with chronic idiopathic diarrhea. HIV Clinical Trials, 18(5-6), 205-213. doi: 10.1080/15284336.2017.1401256. UCSF: Retrieved from: http://www.escholarship.org/uc/item/19601066

© 2017 Informa UK Limited, trading as Taylor & Francis Group. Objectives: To evaluate serum-derived bovine immunoglobulin/protein isolate (SBI) for safety and impact on gastrointestinal (GI) symptoms in HIV patients with chronic idiopathic diarrhea.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c182d8e42cdff51e6d5df4f184e8ae47
http://www.escholarship.org/uc/item/19601066