Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Eric M. Walton"'
Autor:
Molly A Matty, Daphne R Knudsen, Eric M Walton, Rebecca W Beerman, Mark R Cronan, Charlie J Pyle, Rafael E Hernandez, David M Tobin
Publikováno v:
eLife, Vol 8 (2019)
Mycobacterium tuberculosis is the leading worldwide cause of death due to a single infectious agent. Existing anti-tuberculous therapies require long treatments and are complicated by multi-drug-resistant strains. Host-directed therapies have been pr
Externí odkaz:
https://doaj.org/article/8861276875c848aca98d4ec17b2b452f
Autor:
W. Jared Brewer, Ana María Xet-Mull, Anne Yu, Mollie I. Sweeney, Eric M. Walton, David M. Tobin
Publikováno v:
Cell reports. 41(11)
During mycobacterial infections, pathogenic mycobacteria manipulate both host immune and stromal cells to establish and maintain a productive infection. In humans, non-human primates, and zebrafish models of infection, pathogenic mycobacteria produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1f880829cd857e9d31998f7868ff3a
https://pubmed.ncbi.nlm.nih.gov/36516756
https://pubmed.ncbi.nlm.nih.gov/36516756
Autor:
Anshuman Das, Madhuvanthi Vijayan, Eric M. Walton, V. Grace Stafford, David N. Fiflis, Aravind Asokan
Publikováno v:
Journal of virology. 96(4)
The single-stranded DNA genome of adeno-associated viruses (AAV) undergoes second-strand synthesis and transcription in the host cell nucleus. While wild-type AAV genomes are naturally silenced upon integration into the host genome, recombinant AAV (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514ca69bcda8d165fdd2e556cae523cd
https://pubmed.ncbi.nlm.nih.gov/34878926
https://pubmed.ncbi.nlm.nih.gov/34878926
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0138949 (2015)
Transgenic labeling of innate immune cell lineages within the larval zebrafish allows for real-time, in vivo analyses of microbial pathogenesis within a vertebrate host. To date, labeling of zebrafish macrophages has been relatively limited, with the
Externí odkaz:
https://doaj.org/article/3ed02d6d5e7e4e95b475a3b7ac432852
Autor:
GuangJun Zhang, Chang Ding, Abby Pei Lemke, Yueyang Wang, Wenqing Zhou, Tianqi Wang, Eric M. Walton, Qing Deng, David M. Tobin, Ramizah Syahirah, Alan Y. Hsu, Sung Jun Park
Publikováno v:
J Cell Sci
CRISPR/Cas9-based tissue-specific knockout techniques are essential for probing the functions of genes in embryonic development and disease using zebrafish. However, the lack of capacity to perform gene-specific rescue or live imaging in the tissue-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968e9b1d970477d79910ddada896438f
https://doi.org/10.1242/jcs.258574
https://doi.org/10.1242/jcs.258574
Autor:
Yueyang Wang, Ramizah Syahirah, Abby Pei Lemke, David M. Tobin, Wenqing Zhou, Tianqi Wang, Qing Deng, Chang Ding, Alan Y. Hsu, Eric M. Walton
Tissue-specific knockout techniques are widely applied in biological studies to probe the tissue-specific roles of specific genes in physiology, development, and disease. CRISPR/Cas9 is a widely used technology to perform fast and efficient genome ed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::504dbc266427ab458730fab3c4105c68
https://doi.org/10.1101/2020.07.27.223008
https://doi.org/10.1101/2020.07.27.223008
Autor:
Mark R. Cronan, Rebecca W. Beerman, Eric M. Walton, Daphne R Knudsen, Charlie J. Pyle, David M. Tobin, Molly A. Matty, Rafael E Hernandez
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
Mycobacterium tuberculosis is the leading worldwide cause of death due to a single infectious agent. Existing anti-tuberculous therapies require long treatments and are complicated by multi-drug-resistant strains. Host-directed therapies have been pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c4c6c70b1e4eb9934916a0b19d7310
https://elifesciences.org/articles/39123
https://elifesciences.org/articles/39123
Autor:
Eric M. Walton, Molly A. Matty, Mark R. Cronan, David M. Tobin, Daphne R Knudsen, Rebecca W. Beerman, Rafael E Hernandez, Charlie J. Pyle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5b57b68fd207cdd1ca9d432a666650c
https://doi.org/10.7554/elife.39123.028
https://doi.org/10.7554/elife.39123.028
Autor:
Marisa W. Medina, Jerome I. Rotter, Stefan H. Oehlers, David M. Tobin, Elizabeth Theusch, Dennis C. Ko, Yu-Lin Kuang, Trinh T. B. Tram, Eric M. Walton, Liuyang Wang, Colleen M. McClean, Monica I. Alvarez, Sarah J. Dunstan, Nguyen Tran Chinh, Peter M Luo, Luke C. Glover
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Significance Salmonella enterica serovar Typhi ( S . Typhi) causes ∼20 million cases of typhoid fever every year. We carried out a genome-wide association study to identify genetic differences that correlate with the susceptibility of cells from hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a13db2556ca16f5543fc44e63980f54d
https://doi.org/10.1073/pnas.1706070114
https://doi.org/10.1073/pnas.1706070114
Autor:
W. Jared Brewer, Matthew D. Foglia, Mark R. Cronan, Kenneth D. Poss, Eric M. Walton, C.J. Cambier, David M. Tobin, Carolyn R. Bertozzi, Michele Marass, Andrea Rossi, Didier Y.R. Stainier
Publikováno v:
Cell Host & Microbe
Summary Mycobacterial infection leads to the formation of characteristic immune aggregates called granulomas, a process accompanied by dramatic remodeling of the host vasculature. As granuloma angiogenesis favors the infecting mycobacteria, it may be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14203a80b254d28397ee3ab149473f14
https://doi.org/10.1016/j.chom.2018.09.004
https://doi.org/10.1016/j.chom.2018.09.004