Výsledky vyhledávání - "Eric M. Sussman"

Temperature dependence of nickel ion release from nitinol medical devices

Autor: Huiyu Shi, Joshua E. Soneson, David M. Saylor, Shiril Sivan, Matthew Di Prima, Jason D. Weaver, Paul Turner, Eric M. Sussman

Publikováno v: Journal of Biomedical Materials Research Part B: Applied Biomaterials. 109:1188-1197

Nitinol exhibits unique (thermo)mechanical properties that make it central to the design of many medical devices. However, nitinol nominally contains 50 atomic percent nickel, which if released in sufficient quantities, can lead to adverse health eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5323024c5268e005e2c5e0b726c4939
https://doi.org/10.1002/jbm.b.34781

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Cytotoxicity, cellular uptake and apoptotic responses in human coronary artery endothelial cells exposed to ultrasmall superparamagnetic iron oxide nanoparticles

Autor: Peter L. Goering, Teresa Palacios-Hernández, Daysi Diaz-Diestra, Shelby A. Skoog, Eric M. Sussman, Bhaskara Vijaya Chikkaveeraiah, Peter Petrochenko, Yong Wu, Xing Tang, Alexander K. Nguyen

Publikováno v: Journal of Applied Toxicology. 40:918-930

Ultrasmall superparamagnetic iron oxide nanoparticles (USPION) possess reactive surfaces, are metabolized and exhibit unique magnetic properties. These properties are desirable for designing novel theranostic biomedical products; however, toxicity me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f28ebe4371031edefcc4a0e363b0f6
https://doi.org/10.1002/jat.3953

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An Introduction to the Benchmarking and Publications for Non-Targeted Analysis Working Group

Publikováno v: Anal Chem

Non-targeted analysis (NTA) encompasses a rapidly evolving set of mass spectrometry techniques aimed at characterizing the chemical composition of complex samples, identifying unknown compounds, and/or classifying samples, without prior knowledge reg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ff5304cc9a42768c133e7ebe7800ec
https://pubmed.ncbi.nlm.nih.gov/34842413

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Aseptic and septic prosthetic joint loosening: Impact of biomaterial wear on immune cell function, inflammation, and infection

Autor: Eric M. Sussman, Jan P. Stegemann, Nicholas A. Hodges

Publikováno v: Biomaterials. 278

The success of total joint replacements has led to consistent growth in the use of arthroplasty in progressively younger patients. However, more than 10 percent of patients require revision surgeries due to implant failure caused by osteolytic loosen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37c10d2ee07c9c29bd17fd11d91f2bee
https://pubmed.ncbi.nlm.nih.gov/34564034

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Leveraging Extraction Testing to Predict Patient Exposure to Polymeric Medical Device Leachables Using Physics-based Models

Autor: Keaton Nahan, Robert M. Elder, Saloni Shah, David M. Saylor, Eric M. Sussman, Anne Talley, Paul Turner, Timothy V Duncan

Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology. 178(1)

Toxicological risk assessment approaches are increasingly being used in lieu of animal testing to address toxicological concerns associated with release of chemical constituents from polymeric medical device components. These approaches currently rel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd526279d3a5b213d9353cec36f9a696
https://pubmed.ncbi.nlm.nih.gov/33111940

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Screening for extractables in additive-manufactured acrylonitrile butadiene styrene orthopedic cast

Autor: Berk Oktem, Lester Schultheis, Eric M. Sussman, Samanthi Wickramasekara, Keaton Nahan

Publikováno v: Talanta. 212

The use of additive-manufactured components in medical applications, specifically medical devices (e.g., orthopedic casts), has increased in recent years. Such devices may be fabricated at the point of care using consumer-grade additive manufacturing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d48b269fa7e4099ea0da4a764a0d47e
https://pubmed.ncbi.nlm.nih.gov/32113524

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Predicting patient exposure to nickel released from cardiovascular devices using multi-scale modeling

Autor: Vaishnavi Chandrasekar, Eric M. Sussman, Brent A. Craven, Ronald P. Brown, David M. Saylor, David D. Simon

Publikováno v: Acta biomaterialia. 70

Many cardiovascular device alloys contain nickel, which if released in sufficient quantities, can lead to adverse health effects. However, in-vivo nickel release from implanted devices and subsequent biodistribution of nickel ions to local tissues an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b30fd108896cf3a0242560cb9861ee2
https://pubmed.ncbi.nlm.nih.gov/29408403

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Porous Implants Modulate Healing and Induce Shifts in Local Macrophage Polarization in the Foreign Body Reaction

Autor: Eric M. Sussman, Michelle C. Halpin, Buddy D. Ratner, Randall T. Moon, Jeanot Muster

Publikováno v: Annals of Biomedical Engineering. 42:1508-1516

The foreign body reaction (FBR) to implanted materials is of critical importance when medical devices require biological integration and vascularization to support their proper function (e.g., transcutaneous devices, implanted drug delivery systems,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fe0de7de103e2af95598e42d6d5874
https://doi.org/10.1007/s10439-013-0933-0

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