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of 6
pro vyhledávání: '"Eric M. Patrick"'
Autor:
Basma M. Klump, Gloria I. Perez, Eric M. Patrick, Kate Adams-Boone, Scott B. Cohen, Li Han, Kefei Yu, Jens C. Schmidt
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112577- (2023)
Summary: Localization of a variety of RNAs to non-membrane-bound cellular compartments such as nucleoli and Cajal bodies is critical for their stability and function. The molecular mechanisms that underly the recruitment and exclusion of RNAs from th
Externí odkaz:
https://doaj.org/article/f4ed1d519dc94c5390ee2c08bbcc1031
Publikováno v:
Nature chemical biology
Telomere maintenance by telomerase is essential for continuous proliferation of human cells and is vital for the survival of stem cells and 90% of cancer cells. To compensate for telomeric DNA lost during DNA replication, telomerase processively adds
Autor:
Kasun B. Senanayake, Rajeev Yadav, Kyle D. Cotter, Eric M. Patrick, Andrea A. Putnam, Eckhard Jankowski, Matthew J. Comstock
Publikováno v:
Biophysical Journal. 122:10a
Autor:
Eric M. Patrick Dassas
Publikováno v:
ASSOCIATION CULTURELLE FRANC0-COREENNE. :391-425
Publikováno v:
The Journal of Physical Chemistry Letters
Fluorescent nucleotide analogues, such as 2-aminopurine (2AP) and pyrrolo-C (PyC), have been extensively used to study nucleic acid local conformational dynamics in bulk experiments. Here we present a proof-of-principle approach using 2AP and PyC flu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27ab95e6f78ce08fc9230ca0a7e65ec
http://hdl.handle.net/10044/1/37465
http://hdl.handle.net/10044/1/37465
Publikováno v:
Biophysical Journal. 108:14a-15a
We present single-molecule high-resolution optical trapping measurements of RNA unwinding by the Ski2-like nuclear helicase Mtr4p both alone and within the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex. RNA helicases such as Mtr4p play key roles in