Heme Dissociation from Myoglobin in the Presence of the Zwitterionic Detergent N,N-Dimethyl-N-Dodecylglycine Betaine: Effects of Ionic Liquids

Autor: Eric M. Kohn, Joshua Y. Lee, Anthony Calabro, Timothy D. Vaden, Gregory A. Caputo

Publikováno v: Biomolecules, Vol 8, Iss 4, p 126 (2018)

We have investigated myoglobin protein denaturation using the zwitterionic detergent Empigen BB (EBB, N,N-Dimethyl-N-dodecylglycine betaine). A combination of absorbance, fluorescence, and circular dichroism spectroscopic measurements elucidated the

Externí odkaz: https://doaj.org/article/a5f86b9964b549b985f06bba04368d56

Peptide‐assisted supramolecular polymerization of the anionic porphyrin meso‐tetra ( 4‐sulfonatophenyl )porphine

Autor: Eric M. Kohn, David J. Shirley, Nicole M. Hinds, H. Christopher Fry, Gregory A. Caputo

Publikováno v: Peptide Science. 114

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::137dacf4935373171a09af62ffea27cf
https://doi.org/10.1002/pep2.24288

Self-Assembling Catalytic Peptide Nanomaterials Capable of Highly Efficient Peroxidase Activity

Autor: Inhye Kim, Ivan V. Korendovych, Eric M. Kohn, Liam R. Marshall, Oleksii Zozulia

Publikováno v: Chemistry

The self-assembly of short peptides gives rise to versatile nanomaterials capable of promoting efficient catalysis. We have shown that short, seven-residue peptides bind hemin to produce functional catalytic materials which display highly efficient p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5780c20ad52a9a799bc7bd3eab12217d
https://pubmed.ncbi.nlm.nih.gov/33460473

Role of Cationic Side Chains in the Antimicrobial Activity of C18G

Autor: David J. Shirley, Lubov Arotsky, Michael Urban, Benjamin R. Carone, Eric M. Kohn, Angela L. Picciano, Zachary Ridgway, Gregory A. Caputo

Publikováno v: Molecules; Volume 23; Issue 2; Pages: 329
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 23, Iss 2, p 329 (2018)

Antimicrobial peptides (AMPs) have been an area of great interest, due to the high selectivity of these molecules toward bacterial targets over host cells and the limited development of bacterial resistance to these molecules throughout evolution. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6f4c1fec7e9af84a75107d6dcd6083

Effects of Ionic Liquid Alkyl Chain Length on Denaturation of Myoglobin by Anionic, Cationic, and Zwitterionic Detergents

Autor: Gregory A. Caputo, Timothy D. Vaden, Eric M. Kohn, Katherine M Selfridge, Joshua Y. Lee

Publikováno v: Biomolecules, Vol 9, Iss 7, p 264 (2019)
Biomolecules
Volume 9
Issue 7

The unique electrochemical properties of ionic liquids (ILs) have motivated their use as solvents for organic synthesis and green energy applications. More recently, their potential in pharmaceutical chemistry has prompted investigation into their ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4302dccf81083ad2736a19b068a869a0
https://doi.org/10.3390/biom9070264