Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Eric M. George"'
Publikováno v:
Biology of Sex Differences, Vol 11, Iss 1, Pp 1-11 (2020)
Abstract Soluble vascular endothelial growth factor receptor-1 (sFlt-1) is an anti-angiogenic protein which is secreted by numerous cell types and acts as a decoy receptor for the angiogenic protein vascular endothelial growth factor (VEGF). Despite
Externí odkaz:
https://doaj.org/article/0e4a5aeab4d644c280779eb1a4dbd7b2
Publikováno v:
Biology of Sex Differences, Vol 9, Iss 1, Pp 1-11 (2018)
Abstract Preeclampsia is a pregnancy-induced hypertensive disorder resulting from abnormal placentation, which causes factors such as sFlt-1 to be released into the maternal circulation. Though anti-hypertensive drugs and magnesium sulfate can be giv
Externí odkaz:
https://doaj.org/article/b66bb0f94c3944f5878e37f4ae11ce7a
Publikováno v:
Biology Open, Vol 5, Iss 3, Pp 372-380 (2016)
Mammals express six major somatic linker histone subtypes, all of which display dynamic binding to chromatin, characterized by transient binding at a given location followed by rapid translocation to a new site. Using photobleaching techniques, we sy
Externí odkaz:
https://doaj.org/article/f731ca48017c4b308187c8226871c47c
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 12 (2017)
BackgroundPreeclampsia is a hypertensive syndrome that complicates 3% to 5% of pregnancies in the United States. Preeclampsia originates from an improperly vascularized and ischemic placenta that releases factors that drive systemic pathophysiology.
Externí odkaz:
https://doaj.org/article/e156a79a396049f3ae33d9627d9fa59f
Publikováno v:
International Journal of Hypertension, Vol 2012 (2012)
One of the most prevalent complications of pregnancy is preeclampsia, a hypertensive disorder which is a leading cause of maternal and perinatal morbidity and premature birth with no effective pharmacological intervention. While the underlying cause
Externí odkaz:
https://doaj.org/article/324670a97a404be58d0bcda07bb144a5
Publikováno v:
Hypertension
Preeclampsia is characterized by the development of elevated blood pressure during the second and third trimesters of pregnancy that is accompanied by end organ dysfunction. The pathogenesis of preeclampsia is multifactorial but is commonly character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fca16ec543c453af74ce7ed5fc61dd
https://doi.org/10.1161/hypertensionaha.121.17713
https://doi.org/10.1161/hypertensionaha.121.17713
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
The pregnant Dahl salt-sensitive (S) rat is an established preclinical model of superimposed spontaneous preeclampsia characterized by exacerbated hypertension, increased urinary protein excretion, and increased fetal demise. Because of the underlyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20f42c82ceebc2941e50d8197739fdb
https://doi.org/10.1152/ajpregu.00298.2020
https://doi.org/10.1152/ajpregu.00298.2020
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
The endothelial glycocalyx is a specialized extracellular matrix that covers the apical side of vascular endothelial cells, projecting into the lumen of blood vessels. The composition of the glycocalyx has been studied in great detail, and it is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168ad61af319f7891981ef114d4c1e1b
https://doi.org/10.1152/ajpregu.00340.2020
https://doi.org/10.1152/ajpregu.00340.2020
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d8e79b4fb93904c8af309632a76cfa5
https://doi.org/10.1096/fasebj.2022.36.s1.l8024
https://doi.org/10.1096/fasebj.2022.36.s1.l8024
Autor:
Erin B Taylor, Eric M George
Publikováno v:
Endocrinology. 163(8)
Preeclampsia (PE) is a common pregnancy-specific disorder that is a major cause of both maternal and fetal morbidity and mortality. Central to the pathogenesis of PE is the production of antiangiogenic and inflammatory factors by the hypoxic placenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b0847eb755d43e667178b4d83f8f74
https://pubmed.ncbi.nlm.nih.gov/35772781
https://pubmed.ncbi.nlm.nih.gov/35772781