Zobrazeno 1 - 10
of 736
pro vyhledávání: '"Eric M Reiman"'
Autor:
Gemma Salvadó, Rik Ossenkoppele, Nicholas J Ashton, Thomas G Beach, Geidy E Serrano, Eric M Reiman, Henrik Zetterberg, Niklas Mattsson‐Carlgren, Shorena Janelidze, Kaj Blennow, Oskar Hansson
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 5, Pp n/a-n/a (2023)
Abstract Several promising plasma biomarkers for Alzheimer's disease have been recently developed, but their neuropathological correlates have not yet been fully determined. To investigate and compare independent associations between multiple plasma
Externí odkaz:
https://doaj.org/article/adc3e327988745318065d88c1f77d745
Soluble P‐tau217 reflects amyloid and tau pathology and mediates the association of amyloid with tau
Autor:
Niklas Mattsson‐Carlgren, Shorena Janelidze, Randall J Bateman, Ruben Smith, Erik Stomrud, Geidy E Serrano, Eric M Reiman, Sebastian Palmqvist, Jeffrey L Dage, Thomas G Beach, Oskar Hansson
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 6, Pp n/a-n/a (2021)
Abstract Alzheimer’s disease is characterized by β‐amyloid plaques and tau tangles. Plasma levels of phospho‐tau217 (P‐tau217) accurately differentiate Alzheimer’s disease dementia from other dementias, but it is unclear to what degree thi
Externí odkaz:
https://doaj.org/article/aa5bbc2a0e2f418985e204cce77715cb
Autor:
Thomas G Beach, Charles H Adler, Nan Zhang, Geidy E Serrano, Lucia I Sue, Erika Driver-Dunckley, Shayamal H Mehta, Edouard E Zamrini, Marwan N Sabbagh, Holly A Shill, Christine M Belden, David R Shprecher, Richard J Caselli, Eric M Reiman, Kathryn J Davis, Kathy E Long, Lisa R Nicholson, Anthony J Intorcia, Michael J Glass, Jessica E Walker, Michael M Callan, Javon C Oliver, Richard Arce, Richard C Gerkin
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231720 (2020)
Many subjects with neuropathologically-confirmed dementia with Lewy bodies (DLB) are never diagnosed during life, instead being categorized as Alzheimer's disease dementia (ADD) or unspecified dementia. Unrecognized DLB therefore is a critical impedi
Externí odkaz:
https://doaj.org/article/185d07c965d94231a069e5f00e8cea58
Autor:
Michael Malek-Ahmadi, Thomas G Beach, Edward Zamrini, Charles H Adler, Marwan N Sabbagh, Holly A Shill, Sandra A Jacobson, Christine M Belden, Richard J Caselli, Brian K Woodruff, Steven Z Rapscak, Geoffrey L Ahern, Jiong Shi, John N Caviness, Erika Driver-Dunckley, Shyamal H Mehta, David R Shprecher, Bryan M Spann, Pierre Tariot, Kathryn J Davis, Kathy E Long, Lisa R Nicholson, Anthony Intorcia, Michael J Glass, Jessica E Walker, Michael Callan, Jasmine Curry, Brett Cutler, Javon Oliver, Richard Arce, Douglas G Walker, Lih-Fen Lue, Geidy E Serrano, Lucia I Sue, Kewei Chen, Eric M Reiman
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217566 (2019)
BackgroundNeuropathology has demonstrated a high rate of comorbid pathology in dementia due to Alzheimer's disease (ADD). The most common major comorbidity is Lewy body disease (LBD), either as dementia with Lewy bodies (AD-DLB) or Alzheimer's diseas
Externí odkaz:
https://doaj.org/article/20865cfb54d54fcb81882a55f80987e8
Autor:
Stephanie Langella, Kyra Bonta, Yinghua Chen, Yi Su, Daniel Vasquez, David Aguillon, Natalia Acosta-Baena, Ana Y. Baena, Gloria Garcia-Ospina, Margarita Giraldo-Chica, Victoria Tirado, Claudia Muñoz, Silvia Ríos-Romenets, Claudia Guzman-Martínez, Jeremy J. Pruzin, Valentina Ghisays, Joseph F. Arboleda-Velasquez, Kenneth S. Kosik, Pierre N. Tariot, Eric M. Reiman, Francisco Lopera, Yakeel T. Quiroz
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-9 (2024)
Abstract Background Apolipoprotein E (APOE) genotypes have been suggested to influence cognitive impairment and clinical onset in presenilin-1 (PSEN1) E280A carriers for autosomal dominant Alzheimer’s disease (ADAD). Less is known about their impac
Externí odkaz:
https://doaj.org/article/3234fbf9ef1a4a4bae611ce4cce7ba51
Autor:
Jing Qian, Frank J Wolters, Alexa Beiser, Mary Haan, M Arfan Ikram, Jason Karlawish, Jessica B Langbaum, John M Neuhaus, Eric M Reiman, J Scott Roberts, Sudha Seshadri, Pierre N Tariot, Beth McCarty Woods, Rebecca A Betensky, Deborah Blacker
Publikováno v:
PLoS Medicine, Vol 14, Iss 3, p e1002254 (2017)
BACKGROUND:With the onset of prevention trials for individuals at high risk for Alzheimer disease, there is increasing need for accurate risk prediction to inform study design and enrollment, but available risk estimates are limited. We developed ris
Externí odkaz:
https://doaj.org/article/b710f4a52ee946588e0dce05432650b4
Single cell transcriptomes and multiscale networks from persons with and without Alzheimer’s disease
Autor:
Qi Wang, Jerry Antone, Eric Alsop, Rebecca Reiman, Cory Funk, Jaroslav Bendl, Joel T. Dudley, Winnie S. Liang, Timothy L. Karr, Panos Roussos, David A. Bennett, Philip L. De Jager, Geidy E. Serrano, Thomas G. Beach, Kendall Van Keuren-Jensen, Diego Mastroeni, Eric M. Reiman, Benjamin P. Readhead
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The emergence of single nucleus RNA sequencing (snRNA-seq) offers to revolutionize the study of Alzheimer’s disease (AD). Integration with complementary multiomics data such as genetics, proteomics and clinical data provides powerful oppor
Externí odkaz:
https://doaj.org/article/583e7a46c0434985a97259a70db5d4e3
Autor:
Yi Su, Tyler M Blazey, Christopher J Owen, Jon J Christensen, Karl Friedrichsen, Nelly Joseph-Mathurin, Qing Wang, Russ C Hornbeck, Beau M Ances, Abraham Z Snyder, Lisa A Cash, Robert A Koeppe, William E Klunk, Douglas Galasko, Adam M Brickman, Eric McDade, John M Ringman, Paul M Thompson, Andrew J Saykin, Bernardino Ghetti, Reisa A Sperling, Keith A Johnson, Stephen P Salloway, Peter R Schofield, Colin L Masters, Victor L Villemagne, Nick C Fox, Stefan Förster, Kewei Chen, Eric M Reiman, Chengjie Xiong, Daniel S Marcus, Michael W Weiner, John C Morris, Randall J Bateman, Tammie L S Benzinger, Dominantly Inherited Alzheimer Network
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152082 (2016)
Amyloid imaging plays an important role in the research and diagnosis of dementing disorders. Substantial variation in quantitative methods to measure brain amyloid burden exists in the field. The aim of this work is to investigate the impact of meth
Externí odkaz:
https://doaj.org/article/3c1e448b15fa468cb6de83c58a76a317
Autor:
Yi Su, Tyler M Blazey, Christopher J Owen, Jon J Christensen, Karl Friedrichsen, Nelly Joseph-Mathurin, Qing Wang, Russ C Hornbeck, Beau M Ances, Abraham Z Snyder, Lisa A Cash, Robert A Koeppe, William E Klunk, Douglas Galasko, Adam M Brickman, Eric McDade, John M Ringman, Paul M Thompson, Andrew J Saykin, Bernardino Ghetti, Reisa A Sperling, Keith A Johnson, Stephen P Salloway, Peter R Schofield, Colin L Masters, Victor L Villemagne, Nick C Fox, Stefan Förster, Kewei Chen, Eric M Reiman, Chengjie Xiong, Daniel S Marcus, Michael W Weiner, John C Morris, Randall J Bateman, Tammie L S Benzinger, Dominantly Inherited Alzheimer Network
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163669 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0152082.].
Externí odkaz:
https://doaj.org/article/34776afea7e04c56aaf53449f4d482fc
Autor:
Suzan van Amerongen, Surya V. Pulukuri, Fatima Tuz-Zahra, Yorghos Tripodis, Jonathan D. Cherry, Charles Bernick, Yonas E. Geda, Jennifer V. Wethe, Douglas I. Katz, Michael L. Alosco, Charles H. Adler, Laura J. Balcer, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Daniel H. Daneshvar, Elizabeth A. Colasurdo, Jeffrey J. Iliff, Gail Li, Elaine R. Peskind, Martha E. Shenton, Eric M. Reiman, Jeffrey L. Cummings, Robert A. Stern, for the DIAGNOSE CTE Research Project Investigators
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Traumatic encephalopathy syndrome (TES) is defined as the clinical manifestation of the neuropathological entity chronic traumatic encephalopathy (CTE). A core feature of TES is neurobehavioral dysregulation (NBD), a neuropsychiat
Externí odkaz:
https://doaj.org/article/f3d33d808dd64b46a6509a1e9d38248a