Zobrazeno 1 - 10
of 1 169
pro vyhledávání: '"Eric M Reiman"'
Autor:
Stephanie Langella, Kyra Bonta, Yinghua Chen, Yi Su, Daniel Vasquez, David Aguillon, Natalia Acosta-Baena, Ana Y. Baena, Gloria Garcia-Ospina, Margarita Giraldo-Chica, Victoria Tirado, Claudia Muñoz, Silvia Ríos-Romenets, Claudia Guzman-Martínez, Jeremy J. Pruzin, Valentina Ghisays, Joseph F. Arboleda-Velasquez, Kenneth S. Kosik, Pierre N. Tariot, Eric M. Reiman, Francisco Lopera, Yakeel T. Quiroz
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-9 (2024)
Abstract Background Apolipoprotein E (APOE) genotypes have been suggested to influence cognitive impairment and clinical onset in presenilin-1 (PSEN1) E280A carriers for autosomal dominant Alzheimer’s disease (ADAD). Less is known about their impac
Externí odkaz:
https://doaj.org/article/3234fbf9ef1a4a4bae611ce4cce7ba51
Single cell transcriptomes and multiscale networks from persons with and without Alzheimer’s disease
Autor:
Qi Wang, Jerry Antone, Eric Alsop, Rebecca Reiman, Cory Funk, Jaroslav Bendl, Joel T. Dudley, Winnie S. Liang, Timothy L. Karr, Panos Roussos, David A. Bennett, Philip L. De Jager, Geidy E. Serrano, Thomas G. Beach, Kendall Van Keuren-Jensen, Diego Mastroeni, Eric M. Reiman, Benjamin P. Readhead
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The emergence of single nucleus RNA sequencing (snRNA-seq) offers to revolutionize the study of Alzheimer’s disease (AD). Integration with complementary multiomics data such as genetics, proteomics and clinical data provides powerful oppor
Externí odkaz:
https://doaj.org/article/583e7a46c0434985a97259a70db5d4e3
Autor:
Suzan van Amerongen, Surya V. Pulukuri, Fatima Tuz-Zahra, Yorghos Tripodis, Jonathan D. Cherry, Charles Bernick, Yonas E. Geda, Jennifer V. Wethe, Douglas I. Katz, Michael L. Alosco, Charles H. Adler, Laura J. Balcer, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Daniel H. Daneshvar, Elizabeth A. Colasurdo, Jeffrey J. Iliff, Gail Li, Elaine R. Peskind, Martha E. Shenton, Eric M. Reiman, Jeffrey L. Cummings, Robert A. Stern, for the DIAGNOSE CTE Research Project Investigators
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Traumatic encephalopathy syndrome (TES) is defined as the clinical manifestation of the neuropathological entity chronic traumatic encephalopathy (CTE). A core feature of TES is neurobehavioral dysregulation (NBD), a neuropsychiat
Externí odkaz:
https://doaj.org/article/f3d33d808dd64b46a6509a1e9d38248a
Autor:
Robert A. Stern, Diana Trujillo-Rodriguez, Yorghos Tripodis, Surya V. Pulukuri, Michael L. Alosco, Charles H. Adler, Laura J. Balcer, Charles Bernick, Zachary Baucom, Kenneth L. Marek, Michael D. McClean, Keith A. Johnson, Ann C. McKee, Thor D. Stein, Jesse Mez, Joseph N. Palmisano, Jeffrey L. Cummings, Martha E. Shenton, Eric M. Reiman, for the DIAGNOSE CTE Research Project Investigators
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Background Exposure to repetitive head impacts (RHI) in American football players can lead to cognitive impairment and dementia due to neurodegenerative disease, particularly chronic traumatic encephalopathy (CTE). The pathognomonic lesion o
Externí odkaz:
https://doaj.org/article/c3bdde97fa634c768c7e8fc5839a2456
Autor:
Stephanie Langella, N. Gil Barksdale, Daniel Vasquez, David Aguillon, Yinghua Chen, Yi Su, Natalia Acosta-Baena, Juliana Acosta-Uribe, Ana Y. Baena, Gloria Garcia-Ospina, Margarita Giraldo-Chica, Victoria Tirado, Claudia Muñoz, Silvia Ríos-Romenets, Claudia Guzman-Martínez, Gabriel Oliveira, Hyun-Sik Yang, Clara Vila-Castelar, Jeremy J. Pruzin, Valentina Ghisays, Joseph F. Arboleda-Velasquez, Kenneth S. Kosik, Eric M. Reiman, Francisco Lopera, Yakeel T. Quiroz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract Autosomal dominant Alzheimer’s disease (ADAD) is genetically determined, but variability in age of symptom onset suggests additional factors may influence cognitive trajectories. Although apolipoprotein E (APOE) genotype and educational at
Externí odkaz:
https://doaj.org/article/9a1d6c4d47d84daea1bb1b579cc1275f
Autor:
Michael Malek-Ahmadi, Yi Su, Valentina Ghisays, Ji Luo, Vivek Devadas, Yinghua Chen, Wendy Lee, Hillary Protas, Kewei Chen, Henrik Zetterberg, Kaj Blennow, Richard J. Caselli, Eric M. Reiman
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-10 (2023)
Abstract Background Plasma neurofilament light (NfL) is an indicator of neurodegeneration and/or neuroaxonal injury in persons with Alzheimer’s disease (AD) and a wide range of other neurological disorders. Here, we characterized and compared plasm
Externí odkaz:
https://doaj.org/article/1e0baaa1053d468dacf6da005802ca91
Autor:
Gemma Salvadó, Rik Ossenkoppele, Nicholas J Ashton, Thomas G Beach, Geidy E Serrano, Eric M Reiman, Henrik Zetterberg, Niklas Mattsson‐Carlgren, Shorena Janelidze, Kaj Blennow, Oskar Hansson
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 5, Pp 1-16 (2023)
Abstract Several promising plasma biomarkers for Alzheimer's disease have been recently developed, but their neuropathological correlates have not yet been fully determined. To investigate and compare independent associations between multiple plasma
Externí odkaz:
https://doaj.org/article/adc3e327988745318065d88c1f77d745
Autor:
Michael L. Alosco, William B. Barr, Sarah J. Banks, Jennifer V. Wethe, Justin B. Miller, Surya Vamsi Pulukuri, Julia Culhane, Yorghos Tripodis, Charles H. Adler, Laura J. Balcer, Charles Bernick, Megan L. Mariani, Robert C. Cantu, David W. Dodick, Michael D. McClean, Rhoda Au, Jesse Mez, Robert W. Turner, Joseph N. Palmisano, Brett Martin, Kaitlin Hartlage, Jeffrey L. Cummings, Eric M. Reiman, Martha E. Shenton, Robert A. Stern, for the DIAGNOSE CTE Research Project
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Background Patterns of cognitive impairment in former American football players are uncertain because objective neuropsychological data are lacking. This study characterized the neuropsychological test performance of former college and profe
Externí odkaz:
https://doaj.org/article/2279786435c145eaa9f3bad5a7a4c2e1
Autor:
Dorothee Schoemaker, Maria Clara Zanon Zotin, Kewei Chen, Kay C. Igwe, Clara Vila-Castelar, Jairo Martinez, Ana Baena, Joshua T. Fox-Fuller, Francisco Lopera, Eric M. Reiman, Adam M. Brickman, Yakeel T. Quiroz
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-11 (2022)
Abstract Background To promote the development of effective therapies, there is an important need to characterize the full spectrum of neuropathological changes associated with Alzheimer’s disease. In line with this need, this study examined white
Externí odkaz:
https://doaj.org/article/6cea0b3f9fa745c08f5508f5f4e4a33b
Autor:
Hillary Protas, Valentina Ghisays, Dhruman D. Goradia, Robert Bauer, Vivek Devadas, Kewei Chen, Eric M. Reiman, Yi Su
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionTau PET imaging has emerged as an important tool to detect and monitor tangle burden in vivo in the study of Alzheimer’s disease (AD). Previous studies demonstrated the association of tau burden with cognitive decline in probable AD coh
Externí odkaz:
https://doaj.org/article/29bdabdd8a3547f1bc0233a46c32ea4c