Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Eric M Pietras"'
Autor:
Michael J. Nash, Evgenia Dobrinskikh, Dong Wang, Eric M. Pietras, Rachel C. Janssen, Jacob E. Friedman, Stephanie R. Wesolowski
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102849- (2024)
Summary: Studying fetal hematopoiesis is challenging as hematopoiesis transitions from the liver to bone marrow. Obtaining human samples is not possible, and small animal models may not provide sufficient biological material. Here, we present a proto
Externí odkaz:
https://doaj.org/article/1408351a7a1948bd90187a6ca66f9581
Autor:
James S. Chavez, Jennifer L. Rabe, Katia E. Niño, Harrison H. Wells, Rachel L. Gessner, Taylor S. Mills, Giovanny Hernandez, Eric M. Pietras
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Chronic inflammation is a common feature of aging and numerous diseases such as diabetes, obesity, and autoimmune syndromes and has been linked to the development of hematological malignancy. Blood-forming hematopoietic stem cells (HSC) can contribut
Externí odkaz:
https://doaj.org/article/95336b6d9bfa4ee79efcfe80a9a8020f
Autor:
Michael J. Nash, Evgenia Dobrinskikh, Taylor K. Soderborg, Rachel C. Janssen, Diana L. Takahashi, Tyler A. Dean, Oleg Varlamov, Jon D. Hennebold, Maureen Gannon, Kjersti M. Aagaard, Carrie E. McCurdy, Paul Kievit, Bryan C. Bergman, Kenneth L. Jones, Eric M. Pietras, Stephanie R. Wesolowski, Jacob E. Friedman
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112393- (2023)
Summary: Maternal overnutrition increases inflammatory and metabolic disease risk in postnatal offspring. This constitutes a major public health concern due to increasing prevalence of these diseases, yet mechanisms remain unclear. Here, using nonhum
Externí odkaz:
https://doaj.org/article/61f8abfb16c94221819b0fcca9d1aea3
Autor:
Giulio Cavalli, Isak W. Tengesdal, Mark Gresnigt, Travis Nemkov, Rob J.W. Arts, Jorge Domínguez-Andrés, Raffaella Molteni, Davide Stefanoni, Eleonora Cantoni, Laura Cassina, Silvia Giugliano, Kiki Schraa, Taylor S. Mills, Eric M. Pietras, Elan Z. Eisenmensser, Lorenzo Dagna, Alessandra Boletta, Angelo D’Alessandro, Leo A.B. Joosten, Mihai G. Netea, Charles A. Dinarello
Publikováno v:
Cell Reports, Vol 35, Iss 1, Pp 108955- (2021)
Summary: Trained immunity (TI) is a de facto innate immune memory program induced in monocytes/macrophages by exposure to pathogens or vaccines, which evolved as protection against infections. TI is characterized by immunometabolic changes and histon
Externí odkaz:
https://doaj.org/article/090779f385b2426584b8720869662ba6
Autor:
James S. Chavez, Jennifer L. Rabe, Giovanny Hernandez, Taylor S. Mills, Katia E. Niño, Pavel Davizon-Castillo, Eric M. Pietras
Publikováno v:
Cells, Vol 11, Iss 4, p 680 (2022)
The transcription factor PU.1 is a critical regulator of lineage fate in blood-forming hematopoietic stem cells (HSC). In response to pro-inflammatory signals, such as the cytokine IL-1β, PU.1 expression is increased in HSC and is associated with my
Externí odkaz:
https://doaj.org/article/b3e5fe7c3d834606a607973c9699bafb
Autor:
Carl A. Mitchell, Evgenia V. Verovskaya, Fernando J. Calero-Nieto, Oakley C. Olson, James W. Swann, Xiaonan Wang, Aurélie Hérault, Paul V. Dellorusso, Si Yi Zhang, Arthur Flohr Svendsen, Eric M. Pietras, Sietske T. Bakker, Theodore T. Ho, Berthold Göttgens, Emmanuelle Passegué
Publikováno v:
Nature Cell Biology. 25:30-41
Autor:
Suhas Sureshchandra, Chi N. Chan, Jacob J. Robino, Lindsay K. Parmelee, Michael J. Nash, Stephanie R. Wesolowski, Eric M. Pietras, Jacob E. Friedman, Diana Takahashi, Weining Shen, Xiwen Jiang, Jon D. Hennebold, Devorah Goldman, William Packwood, Jonathan R. Lindner, Charles T. Roberts, Benjamin J. Burwitz, Ilhem Messaoudi, Oleg Varlamov
Publikováno v:
Stem Cell Reports. 17:2595-2609
Maternal obesity adversely impacts the in utero metabolic environment, but its effect on fetal hematopoiesis remains incompletely understood. During late development, the fetal bone marrow (FBM) becomes the major site where macrophages and B lymphocy
Autor:
Marlie H. Fisher, Gregory D. Kirkpatrick, Brett Stevens, Courtney Jones, Michael Callaghan, Madhvi Rajpurkar, Joy Fulbright, Megan A. Cooper, Jesse Rowley, Christopher C. Porter, Arthur Gutierrez-Hartmann, Kenneth Jones, Craig Jordan, Eric M. Pietras, Jorge Di Paola
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
ETV6 is an ETS family transcription factor that plays a key role in hematopoiesis and megakaryocyte development. Our group and others have identified germline mutations in ETV6 resulting in autosomal dominant thrombocytopenia and predisposition to ma
Externí odkaz:
https://doaj.org/article/5abfc29d644e46a18a3483fbf61edc05
Autor:
Giovanny Hernandez, Taylor S. Mills, Jennifer L. Rabe, James S. Chavez, Susan Kuldanek, Gregory Kirkpatrick, Leila Noetzli, Widian K. Jubair, Michelle Zanche, Jason R. Myers, Brett M. Stevens, Courtney J. Fleenor, Biniam Adane, Charles A. Dinarello, John Ashton, Craig T. Jordan, Jorge Di Paola, James R. Hagman, V. Michael Holers, Kristine A. Kuhn, Eric M. Pietras
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
Rheumatoid arthritis (RA) is a debilitating autoimmune disease characterized by chronic inflammation and progressive destruction of joint tissue. It is also characterized by aberrant blood phenotypes including anemia and suppressed lymphopoiesis that
Externí odkaz:
https://doaj.org/article/eca59744a0444860b5057f8bf06972fb
Autor:
Eric M. Pietras
Publikováno v:
Blood. 141:1650-1652