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pro vyhledávání: '"Eric M Mukherjee"'
Autor:
Agnes S Lo, Xuming Mao, Eric M Mukherjee, Christoph T Ellebrecht, Xiaocong Yu, Marshall R Posner, Aimee S Payne, Lisa A Cavacini
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156800 (2016)
Pemphigus vulgaris (PV) is characterized by IgG1 and IgG4 autoantibodies to desmoglein (Dsg) 3, causing suprabasal blistering of skin and mucous membranes. IgG4 is the dominant autoantibody subclass in PV and correlates with disease activity, whereas
Externí odkaz:
https://doaj.org/article/78fbaa4f7347464dba197027fdbfc74c
Publikováno v:
Annals of allergy, asthmaimmunology : official publication of the American College of Allergy, Asthma,Immunology. 129(3)
Publikováno v:
Postgrad Med
Background: Little is known about patient preference regarding the physical exam in non-urgent primary care settings.Objective: To determine the differences between a patient's expectations of the physical exam and the actual components of the physic
Autor:
Christoph M. Hammers, Sarah M. McDonald, Michael Jeffrey Cho, Gopal Sapparapu, Christoph T. Ellebrecht, James E. Crowe, Aimee S. Payne, Eric M. Mukherjee, Crystal E. Boudreaux
Publikováno v:
The Journal of Immunology. 197:1065-1073
Shared VH1-46 gene usage has been described in B cells reacting to desmoglein 3 (Dsg3) in the autoimmune disease pemphigus vulgaris (PV), as well as B cells responding to rotavirus capsid protein VP6. In both diseases, VH1-46 B cells bearing few to n
Autor:
Eric M. Mukherjee, Aimee S. Payne
Publikováno v:
Science Trends.
Autor:
Qi Zheng, Eun Jung Choi, Shantan Reddy, Xuming Mao, Christoph T. Ellebrecht, Eric M. Mukherjee, Aimee S. Payne
Publikováno v:
Cell reports. 24(9)
Lineage analysis of autoreactive B cells can reveal the origins of autoimmunity. In the autoimmune disease pemphigus vulgaris (PV), desmoglein 3 (DSG3) and DSG1 autoantibodies are predominantly of the IgG4 subclass and less frequently of IgG1 and IgA
Autor:
Stephen L. Helfand, Suzanne Hosier, Alexander S. Brodsky, Sara Hillenmeyer, Charles E. Lawrence, Eric M. Mukherjee, Christoph Schorl, Will Lightfoot, Nan Jiang, Jason G. Wood, Chengyi Chang, Nicola Neretti
Publikováno v:
Aging Cell. 9:971-978
Chromatin structure affects the accessibility of DNA to transcription, repair, and replication. Changes in chromatin structure occur during development, but less is known about changes during aging. We examined the state of chromatin structure and it
Publikováno v:
The Yale Journal of Biology and Medicine
Oncology has been revolutionized by the ability to selectively inhibit the growth of cancerous cells while ostensibly avoiding the disruption of proteins and pathways necessary for normal cellular function. This paradigm has triggered an explosion of
Autor:
Christoph M. Hammers, Eun Jung Choi, Sara A. Farber, Courtney B. Rubin, Marshall R. Posner, Agnes Lo, Lisa A. Cavacini, Arielle R. Nagler, Bruce S. Sachais, Steven H. Kleinstein, Hong Li, Mohamed Uduman, Michael Jeffrey Cho, Eric M. Mukherjee, Preety M. Sharma, Christoph T. Ellebrecht, Ann H. Rux, Xuming Mao, Aimee S. Payne
Publikováno v:
Nature communications
Pemphigus vulgaris (PV) is a potentially fatal blistering disease caused by autoantibodies against desmoglein 3 (Dsg3). Here, we clone anti-Dsg3 antibodies from four PV patients and identify pathogenic VH1-46 autoantibodies from all four patients. Un
Publikováno v:
Journal of Investigative Dermatology. 136:S77