Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Eric M, Darling"'
Publikováno v:
Microsystems & Nanoengineering, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Mechanical properties of biological cells have been shown to correlate with their biomolecular state and function, and therefore methods to measure these properties at scale are of interest. Emerging microfluidic technologies can measure the
Externí odkaz:
https://doaj.org/article/f11bb6c9befb4b60b88178139ccffbdb
Autor:
Patritsia M. Stathatou, Christos E. Athanasiou, Marios Tsezos, John W. Goss, L. Camron Blackburn, Filippos Tourlomousis, Andreas Mershin, Brian W. Sheldon, Nitin P. Padture, Eric M. Darling, Huajian Gao, Neil Gershenfeld
Publikováno v:
Communications Earth & Environment, Vol 3, Iss 1, Pp 1-9 (2022)
Trace concentrations of lead can be rapidly removed from water via biosorption at the cell wall of the yeast Saccharomyces cerevisiae, according to adsorption kinetic experiments, spectroscopic analyses and nanomechanical characterization.
Externí odkaz:
https://doaj.org/article/5c8ca3e03e40412c9409e2eb491e063b
Publikováno v:
Cellular and Molecular Bioengineering. 15:587-597
The chondrogenic response of adipose-derived stem cells (ASCs) is often assessed using 3D micromass protocols that use upwards of hundreds of thousands of cells. Scaling these systems up for high-throughput testing is technically challenging and wast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf63d61b885a232f0d6616682c6ce2ba
https://doi.org/10.1007/s12195-022-00746-8
https://doi.org/10.1007/s12195-022-00746-8
Autor:
Jessica S. Sadick, Eric M. Darling
Publikováno v:
BioTechniques, Vol 63, Iss 6, Pp 275-280 (2017)
Accurately characterizing cellular subpopulations is essential for elucidating the mechanisms underlying normal and pathological biology. Isolation of specific cell types can be accomplished by labeling unique cell-associated proteins with fluorescen
Externí odkaz:
https://doaj.org/article/d15cf105401f4bbd8fb0cada174e02c5
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Lamin A and lamin C isoforms of the gene LMNA are major structural and mechanotransductive components of the nuclear lamina. Previous reports have proposed lamin A as the isoform with the most dominant contributions to cellular mechanophenotype. Rece
Externí odkaz:
https://doaj.org/article/a3790abff1e640aaa61232956c74e2da
Publikováno v:
Cell Mol Bioeng
INTRODUCTION: Antibodies are an essential research tool for labeling surface proteins but can potentially influence the behavior of proteins and cells to which they bind. Because of this, researchers and clinicians are interested in the persistence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd65b04e17aa3845430d91dd0362e516
https://doi.org/10.1007/s12195-021-00670-3
https://doi.org/10.1007/s12195-021-00670-3
Autor:
Megan E. Dempsey, Graylen R. Chickering, Rafael D. González-Cruz, Vera C. Fonseca, Eric M. Darling
Publikováno v:
Cell Mol Life Sci
Cellular mechanophenotype is often a defining characteristic of conditions like cancer malignancy/metastasis, cardiovascular disease, lung and liver fibrosis, and stem cell differentiation. However, acquiring living cells based on mechanophenotype is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63252722cf442ae6deadf9f1aa367ac
https://doi.org/10.1007/s00018-022-04351-w
https://doi.org/10.1007/s00018-022-04351-w
Autor:
Brittany M. Neumann, Zachary S. Wilson, Kinga Auguste, Yasmin Roye, Manisha K. Shah, Eric M. Darling, Craig T. Lefort
Neutrophils are rapidly mobilized from the circulation to sites of inflammation. The mechanisms of neutrophil trafficking in the lung are distinct from those in the periphery, in part because the pulmonary capillaries are the primary site of neutroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a935a154d426f4ba0b37d6d0d57bd23a
https://doi.org/10.1101/2022.04.24.489286
https://doi.org/10.1101/2022.04.24.489286
Autor:
Christian Franck, Shane A. Liddelow, Lorin Crawford, Eric M. Darling, Harry C. Cramer, Jessica S. Sadick
Publikováno v:
Ann Biomed Eng
Here we demonstrate a technique to generate proteomic signatures of specific cell types within heterogeneous populations. While our method is broadly applicable across biological systems, we have limited the current work to study neural cell types is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd1f23bfcc52f5e1cdbd457b2d9f3768
https://doi.org/10.1007/s10439-020-02507-y
https://doi.org/10.1007/s10439-020-02507-y
Autor:
Christos E. Athanasiou, Brian W. Sheldon, Nitin P. Padture, Camron Blackburn, John W. Goss, Andreas Mershin, Huajian Gao, Marios Tsezos, Patritsia Maria Stathatou, Eric M. Darling, Neil Gershenfeld, Filippos Tourlomousis
Traces of heavy metals found in water resources, due to mining activities and e-waste discharge, pose a global threat. Conventional treatment processes fail to remove toxic heavy metals, such as lead, from drinking water in a resource-efficient manne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29412ed2a534d28d9f9241dc470efc50
https://doi.org/10.1101/2021.10.07.463380
https://doi.org/10.1101/2021.10.07.463380