Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Eric M, Bachelder"'
Publikováno v:
mSphere, Vol 9, Iss 7 (2024)
ABSTRACT In humans, seasonal influenza viruses cause epidemics. Avian influenza viruses are of particular concern because they can infect multiple species and lead to unpredictable and severe disease. Therefore, there is an urgent need for a universa
Externí odkaz:
https://doaj.org/article/8901e68014a24da88d9bc3f73a10c799
Autor:
Dylan A. Hendy, Erik S. Pena, Luis Ontiveros‐Padilla, Timothy A. Dixon, Denzel D. Middleton, Grace L. Williamson, Nicole Rose Lukesh, Sean R. Simpson, Rebeca T. Stiepel, Md Jahirul Islam, Michael A. Carlock, Ted M. Ross, Eric M. Bachelder, Kristy M. Ainslie
Publikováno v:
Bioengineering & Translational Medicine, Vol 9, Iss 2, Pp n/a-n/a (2024)
Abstract Influenza virus outbreaks are a major burden worldwide each year. Current vaccination strategies are inadequate due to antigenic drift/shift of the virus and the elicitation of low immune responses. The use of computationally optimized broad
Externí odkaz:
https://doaj.org/article/e45d7ae58a0e451d9e71585438cf9fcd
Autor:
Luis Ontiveros-Padilla, Cole J. Batty, Dylan A. Hendy, Erik S. Pena, John A. Roque, Rebeca T. Stiepel, Michael A. Carlock, Sean R. Simpson, Ted M. Ross, Soman N. Abraham, Herman F. Staats, Eric M. Bachelder, Kristy M. Ainslie
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Currently licensed vaccine adjuvants offer limited mucosal immunity, which is needed to better combat respiratory infections such as influenza. Mast cells (MCs) are emerging as a target for a new class of mucosal vaccine adjuvants. Here, we developed
Externí odkaz:
https://doaj.org/article/e70567c612c44f1da172b79c933b2fc4
Autor:
M. Shamim Hasan Zahid, Monica M. Johnson, Robert J. Tokarski, II, Abhay R. Satoskar, James R. Fuchs, Eric M. Bachelder, Kristy M. Ainslie
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 10, Iss , Pp 125-132 (2019)
Visceral leishmaniasis (VL) is associated with treatment complications due to the continued growth of resistant parasites toward currently available pathogen-directed therapeutics. To limit the emergence and combat resistant parasites there is a need
Externí odkaz:
https://doaj.org/article/716bfe9e4ea0424e8cf76cbbdedd1a0b
Publikováno v:
Advanced NanoBiomed Research, Vol 1, Iss 3, Pp n/a-n/a (2021)
Vaccines have advanced human health for centuries. To improve upon the efficacy of subunit vaccines they have been formulated into nano/microparticles for infectious diseases. Much progress in the field of polymeric particles for vaccine formulation
Externí odkaz:
https://doaj.org/article/8b43e0eb25c74f689f9cc82a70ab4dba
Publikováno v:
ACS Applied Bio Materials. 6:934-950
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ea5cc2d7ff5c8f70e3673998c823687
https://doi.org/10.1021/acsabm.2c00973
https://doi.org/10.1021/acsabm.2c00973
Publikováno v:
Expert Opinion on Drug Delivery. 20:367-384
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13d12b897aed5323fb60c45ca0605a68
https://doi.org/10.1080/17425247.2023.2176844
https://doi.org/10.1080/17425247.2023.2176844
Autor:
Kuo-Ching Mei, Rebeca T. Stiepel, Emily Bonacquisti, Natalie E. Jasiewicz, Ameya Pravin Chaudhari, Palas B. Tiwade, Eric M. Bachelder, Kristy M. Ainslie, Owen S. Fenton, Juliane Nguyen
Publikováno v:
Biomaterials Science. 11:2693-2698
New lipids are of great interest for drug/gene delivery. We discovered single-tailed heterocyclic carboxamide lipids for stimulating S1P lysate and IFN-alpha responses in macrophages, providing new bioactive lipid biomaterials for immune modulation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e6d67fae18e8de46025180ba985a6b9
https://doi.org/10.1039/d2bm01804g
https://doi.org/10.1039/d2bm01804g
Autor:
Rebeca T, Stiepel, Erik S, Pena, Stephen A, Ehrenzeller, Matthew D, Gallovic, Liubov M, Lifshits, Christopher J, Genito, Eric M, Bachelder, Kristy M, Ainslie
Publikováno v:
Journal of Controlled Release. 351:883-895
Effective drug delivery requires ample dosing at the target tissue while minimizing negative side effects. Drug delivery vehicles such as polymeric nanoparticles (NPs) are often employed to accomplish this challenge. In this work, drug release of num
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c83059266f159c8131826791a0864d1
https://doi.org/10.1016/j.jconrel.2022.09.067
https://doi.org/10.1016/j.jconrel.2022.09.067
Autor:
Matthew D. Gallovic, Robert D. Junkins, Adam M. Sandor, Erik S. Pena, Christopher J. Sample, Ariel K. Mason, Leslee C. Arwood, Rebecca A. Sahm, Eric M. Bachelder, Kristy M. Ainslie, Gregory D. Sempowski, Jenny P.-Y. Ting
Publikováno v:
J Control Release
The COVID-19 pandemic highlights the need for effective vaccines against respiratory viruses. An ideal vaccine should induce robust and long-lasting responses with high manufacturing scalability. We used an adjuvant comprised of a Stimulator of Inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20087447a615e18aec17eddcf52b2b7a
https://doi.org/10.1016/j.jconrel.2022.05.017
https://doi.org/10.1016/j.jconrel.2022.05.017