Zobrazeno 1 - 8
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pro vyhledávání: '"Eric L. Finley"'
Autor:
Kevin L. Schey, Eric L. Finley
Publikováno v:
Accounts of Chemical Research. 33:299-306
Oxidative reactions play important roles in a variety of biochemical events ranging from normal metabolism to aging and disease processes. Proteins represent major targets for modification in these reactions, and identification of sites and structure
Publikováno v:
Photochemistry and Photobiology. 68:9-15
Radiolysis of water by ionizing radiation results in the production of pure hydroxyl radicals. This technique, combined with analysis by tandem mass spectrometry (MS/MS), has been used to study the effect of hydroxyl radicals on the intact bovine alp
Autor:
Krishna M. Ella, Kathryn E. Meier, April E. Wisehart-Johnson, Anthony F. McNair, Angela C. S. Gore, Katrina C. Gause, Linda G. Jones, Eric L. Finley, Cynthia D. Bradshaw
Publikováno v:
Cellular Signalling. 10:415-426
High doses of propranolol inhibit phosphatidate phosphohydrolase (PAP) activity in intact cells, thus blocking metabolism of phosphatidic acid (PA), product of the phospholipase D (PLD) reaction. Vasopressin and phorbol ester activate PLD and ERK (ex
Publikováno v:
Photochemistry and Photobiology. 66:635-641
Because UV irradiation of proteins can produce reactive oxygen species and exposure to UV light has been implicated in cataractogenesis, the sites of photooxidation of bovine alpha-crystallin, a major lens protein with molecular chaperone activity, w
Publikováno v:
Biochemical Pharmacology. 53:1823-1832
Thromboxane A 2 (TXA 2 ) interacts with its G-protein coupled receptor, the TP receptor, to produce contraction and proliferation of vascular smooth muscle cells. We have shown previously that proliferation of primary cultures of vascular smooth musc
Autor:
Kevin L. Schey, Eric L. Finley
Publikováno v:
ChemInform. 31
Oxidative reactions play important roles in a variety of biochemical events ranging from normal metabolism to aging and disease processes. Proteins represent major targets for modification in these reactions, and identification of sites and structure
Publikováno v:
Protein science : a publication of the Protein Society. 7(11)
Oxidation is known to affect the structure, activity, and rate of degradation of proteins, and is believed to contribute to a variety of pathological conditions. Metal-catalyzed oxidation (MCO) is a primary oxidizing system in many cell types. In thi
Publikováno v:
Photochemistry and Photobiology. 74:740
The tryptophan metabolite, xanthurenic acid (Xan), is produced through a transamination reaction in high concentrations in human lenses with age and has been isolated from aged human cataractous lenses. It has appreciable absorption between 300 and 4