Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Eric L Weiss"'
Autor:
Magdalena Foltman, Iván Mendez, Joan J Bech-Serra, Carolina de la Torre, Jennifer L Brace, Eric L Weiss, María Lucas, Ethel Queralt, Alberto Sanchez-Diaz
Publikováno v:
PLoS Biology, Vol 21, Iss 8, p e3002263 (2023)
The target of rapamycin (TOR) signalling pathway plays a key role in the coordination between cellular growth and the cell cycle machinery in eukaryotes. The underlying molecular mechanisms by which TOR might regulate events after anaphase remain unk
Externí odkaz:
https://doaj.org/article/19a7d01e0baf49f7883023b5e8db7fa3
Autor:
Gergő Gógl, Kyle D Schneider, Brian J Yeh, Nashida Alam, Alex N Nguyen Ba, Alan M Moses, Csaba Hetényi, Attila Reményi, Eric L Weiss
Publikováno v:
PLoS Biology, Vol 13, Iss 5, p e1002146 (2015)
Eukaryotic cells commonly use protein kinases in signaling systems that relay information and control a wide range of processes. These enzymes have a fundamentally similar structure, but achieve functional diversity through variable regions that dete
Externí odkaz:
https://doaj.org/article/31471c17669943c58389a0fa123abf73
Autor:
Alex N Nguyen Ba, Bob Strome, Jun Jie Hua, Jonathan Desmond, Isabelle Gagnon-Arsenault, Eric L Weiss, Christian R Landry, Alan M Moses
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 12, p e1003977 (2014)
Gene duplication is an important evolutionary mechanism that can result in functional divergence in paralogs due to neo-functionalization or sub-functionalization. Consistent with functional divergence after gene duplication, recent studies have show
Externí odkaz:
https://doaj.org/article/2f338d7e117f41aab6126831fffdba34
Cell morphogenesis proteins are translationally controlled through UTRs by the Ndr/LATS target Ssd1.
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85212 (2014)
Eukaryotic cells control their growth and morphogenesis to maintain integrity and viability. Free-living cells are further challenged by their direct interaction with the environment and in many cases maintain a resilient cell wall to stay alive unde
Externí odkaz:
https://doaj.org/article/1a0164f69d884cb49a567f5c3bea55d8
Autor:
Jonathan Hsu, Eric L Weiss
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78334 (2013)
Hippo pathways are ancient signaling systems that contribute to cell growth and proliferation in a wide diversity of eukaryotes, and have emerged as a conserved regulator of organ size control in metazoans. In budding yeast, a Hippo signaling pathway
Externí odkaz:
https://doaj.org/article/e7c1f3e6e7a0411ca74c952cfcf4c410
Autor:
Emily Mazanka, Jess Alexander, Brian J Yeh, Patrick Charoenpong, Drew M Lowery, Michael Yaffe, Eric L Weiss
Publikováno v:
PLoS Biology, Vol 6, Iss 8, p e203 (2008)
Cell fate can be determined by asymmetric segregation of gene expression regulators. In the budding yeast Saccharomyces cerevisiae, the transcription factor Ace2 accumulates specifically in the daughter cell nucleus, where it drives transcription of
Externí odkaz:
https://doaj.org/article/b6f0d5532677435fbdc486a3e45e5dcf
Publikováno v:
Biochemistry
Biochemistry, 2020, 59 (17), pp.1688-1700. ⟨10.1021/acs.biochem.9b01096⟩
Biochemistry, 2020, 59 (17), pp.1688-1700. ⟨10.1021/acs.biochem.9b01096⟩
Ndr/Lats kinases bind Mob coactivator proteins to form complexes that are essential and deeply conserved components of “Hippo” signaling pathways, which control cell proliferation and morphogenesis in eukaryotes. All Ndr/Lats kinases have a chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25222b33eb59adb92e4be641cc261ee4
https://hal.science/hal-03700734
https://hal.science/hal-03700734
Autor:
David T. Krist, Benjamin W. Parker, Eric L. Weiss, Edward J. Goncz, Alexey I. Nesvizhskii, Alexander V. Statsyuk
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(42)
Short linear peptide motifs that are intracellular ligands of folded proteins are a modular, incompletely understood molecular interaction language in signaling systems. Such motifs, which frequently occur in intrinsically disordered protein regions,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8ba7ca084db678192b1ea8a7c83af4
https://pubmed.ncbi.nlm.nih.gov/31578253
https://pubmed.ncbi.nlm.nih.gov/31578253
Asymmetric segregation of cellular factors during cell division produces two cells with different identities. This asymmetry underlies cell fate decisions as well as the ability to self-renew. Asymmetric segregation of protein and RNA to the growing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd3aa4bfd538fb4ef86c4912a5131a54
https://doi.org/10.1101/483388
https://doi.org/10.1101/483388
Autor:
Benjamin W. Parker, David T. Krist, Edward J. Goncz, Alexander V. Statsyuk, Eric L. Weiss, Alexey I. Nesvizhskii
Unstructured peptides, or linear motifs, present a poorly understood molecular language within the context of cellular signaling. These modular regions are often short, unstructured and interact weakly and transiently with folded target proteins. Thu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba4398ee3113993aa2749b51025cfff