Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Eric L, Campbell"'
Autor:
Ricardo Calderon-Gonzalez, Alix Lee, Guillermo Lopez-Campos, Steven J. Hancock, Joana Sa-Pessoa, Amy Dumigan, Ronan McMullan, Eric L. Campbell, Jose A. Bengoechea
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Klebsiella pneumoniae is a leading cause of nosocomial and community acquired infections, making K. pneumoniae the pathogen that is associated with the second largest number of deaths attributed to any antibiotic resistant infection. K. pneu
Externí odkaz:
https://doaj.org/article/8d74ee6a8a224fe895fcd318972ecd86
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 3, Pp 329-337 (2017)
Inflammatory responses in the intestinal mucosa inevitably result in the recruitment of neutrophils (polymorphonuclear leukocytes [PMNs]). Epithelial cells that line the mucosa play an integral role in the recruitment, maintenance, and clearance of P
Externí odkaz:
https://doaj.org/article/c257599951ca46458aaa88a15b34cace
Autor:
Biniam Adane, Haobin Ye, Nabilah Khan, Shanshan Pei, Mohammad Minhajuddin, Brett M. Stevens, Courtney L. Jones, Angelo D’Alessandro, Julie A. Reisz, Vadym Zaberezhnyy, Maura Gasparetto, Tzu-Chieh Ho, Kathleen K. Kelly, Jason R. Myers, John M. Ashton, Julie Siegenthaler, Tsutomu Kume, Eric L. Campbell, Daniel A. Pollyea, Michael W. Becker, Craig T. Jordan
Publikováno v:
Cell Reports, Vol 27, Iss 1, Pp 238-254.e6 (2019)
Summary: The NADPH-dependent oxidase NOX2 is an important effector of immune cell function, and its activity has been linked to oncogenic signaling. Here, we describe a role for NOX2 in leukemia-initiating stem cell populations (LSCs). In a murine mo
Externí odkaz:
https://doaj.org/article/d5544c2b5ce54bd09d30079612acafba
Autor:
Ricardo Calderon-Gonzalez, Alix Lee, Guillermo Lopez-Campos, Steven J. Hancock, Joana Sa-Pessoa, Amy Dumigan, Ronan McMullan, Eric L. Campbell, Jose A. Bengoechea
Klebsiella pneumoniae is a leading cause of nosocomial and community acquired infections, making K. pneumoniae the second pathogen associated with the most deaths attributed to any antibiotic resistant infection. K. pneumoniae colonises the nasophary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d10a718a07518732d50c71bbe1a0d71
https://doi.org/10.1101/2022.10.03.510744
https://doi.org/10.1101/2022.10.03.510744
Autor:
Juliet Hammer, Eóin N. McNamee, Rachel Harris, Kelley E. Capocelli, Glenn T. Furuta, Kathryn A. Biette, Caleb J. Kelly, Sean P. Colgan, Hiroshi Nakagawa, Nathalie Nguyen, Joanne C. Masterson, Stefan F. Ehrentraut, Faria N. Ahmed, Louise E. Glover, Bejan Saeedi, Lindsay Hosford, Shahan D. Fernando, Eric L. Campbell, James J. Lee
Publikováno v:
Journal of Clinical Investigation. 129:3224-3235
Epithelial barrier dysfunction is a significant factor in many allergic diseases, including eosinophilic esophagitis (EoE). Infiltrating leukocytes and tissue adaptations increase metabolic demands and decrease oxygen availability at barrier surfaces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d856bf92de997e3efdc2256015b0a44
https://doi.org/10.1172/jci126744
https://doi.org/10.1172/jci126744
Autor:
Seth T. Walk, Douglas J. Kominsky, Steve D. Swain, Brittany D. Jenkins, Eric L. Campbell, Heather M Grifka-Walk, Nathan A. Blaseg, Benjamin Deuling
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(6)
Intestinal epithelial cells (IEC) are crucial for maintaining proper digestion and overall homeostasis of the gut mucosa. IEC proliferation and differentiation are tightly regulated by well described pathways, however, relatively little is known abou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab828d8fcc5c8d2dba3643ae0e6de46
https://pubmed.ncbi.nlm.nih.gov/34042222
https://pubmed.ncbi.nlm.nih.gov/34042222
Publikováno v:
Proc Natl Acad Sci U S A
Campbell, E 2020, ' Microbiota-derived butyrate dynamically regulates intestinal homeostasis through regulation of actin-associated protein synaptopodin. ', Proceedings of the National Academy of Sciences of the United States of America . https://doi.org/10.1073/pnas.1917597117
Campbell, E 2020, ' Microbiota-derived butyrate dynamically regulates intestinal homeostasis through regulation of actin-associated protein synaptopodin. ', Proceedings of the National Academy of Sciences of the United States of America . https://doi.org/10.1073/pnas.1917597117
The intestinal mucosa exists in dynamic balance with trillions of luminal microbes. Disruption of the intestinal epithelial barrier, commonly observed in mucosal inflammation and diseases such as inflammatory bowel diseases (IBDs), is often associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::526dd1600ef44574b3b7de4d1d90415a
https://pubmed.ncbi.nlm.nih.gov/32398370
https://pubmed.ncbi.nlm.nih.gov/32398370
Autor:
Eric L. Campbell, Sean P. Colgan
Publikováno v:
Nat Rev Gastroenterol Hepatol
Redox signalling in the gastrointestinal mucosa is held in an intricate balance. Potent microbicidal mechanisms can be used by infiltrating immune cells, such as neutrophils, to protect compromised mucosae from microbial infection through the generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c70139e2c3bbb11b8a04316e141424e
https://doi.org/10.1038/s41575-018-0079-5
https://doi.org/10.1038/s41575-018-0079-5
Autor:
Jordi M. Lanis, Ruth Wang, Sean P. Colgan, Nichole Welch, Daniel J. Kao, Matthew S Goldberg, Ian M. Cartwright, Valerie F. Curtis, Krista M. Burney, J. Scott Lee, Caroline H. T. Hall, Eric L. Campbell
Publikováno v:
Molecular Biology of the Cell
Extracellular adenosine signaling is established as a protective component in mucosal inflammatory responses. The sources of extracellular adenosine include enzymatic processing from nucleotides, such as ATP and AMP, that can be liberated from a vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553aa0c181dff2047d7288a6c1de9d48
https://doi.org/10.1091/mbc.e18-06-0377
https://doi.org/10.1091/mbc.e18-06-0377
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Hall, C H T, Campbell, E L & Colgan, S P 2017, ' Neutrophils as Components of Mucosal Homeostasis ', Cellular and Molecular Gastroenterology and Hepatology, vol. 4, no. 3, pp. 329-337 . https://doi.org/10.1016/j.jcmgh.2017.07.001
Hall, C H T, Campbell, E L & Colgan, S P 2017, ' Neutrophils as Components of Mucosal Homeostasis ', Cellular and Molecular Gastroenterology and Hepatology, vol. 4, no. 3, pp. 329-337 . https://doi.org/10.1016/j.jcmgh.2017.07.001
Inflammatory responses in the intestinal mucosa inevitably result in the recruitment of neutrophils (polymorphonuclear leukocytes [PMNs]). Epithelial cells that line the mucosa play an integral role in the recruitment, maintenance, and clearance of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c200733bc17426b28836c8bf6b2ea9
https://doi.org/10.1016/j.jcmgh.2017.07.001
https://doi.org/10.1016/j.jcmgh.2017.07.001