Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Eric Kofoid"'
Publikováno v:
Genetics, vol 214, iss 2
In the Cairns-Foster adaptive mutation system, lac mutant cells are plated on lactose medium where 50 revertant colonies accumulate over 5 days above a non-growing lawn. A new model attributes this behavior to selective... The Escherichia coli system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef290102bcb0888648c43959edfc402
https://doi.org/10.1534/genetics.119.302754
https://doi.org/10.1534/genetics.119.302754
Publikováno v:
Genetics
The Escherichia coli system of Cairns and Foster employs a lac frameshift mutation that reverts rarely (10(−9)/cell/division) during unrestricted growth. However, when 10(8) cells are plated on lactose medium, the nongrowing lawn produces ∼50 Lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f960f6ebda0d0c43ffe9e458b62e1ae
https://pubmed.ncbi.nlm.nih.gov/31810989
https://pubmed.ncbi.nlm.nih.gov/31810989
Publikováno v:
Genetics. 192:397-415
Duplications are often attributed to “unequal recombination” between separated, directly repeated sequence elements (>100 bp), events that leave a recombinant element at the duplication junction. However, in the bacterial chromosome, duplications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b1dd41eb51c0d19525809a48de8d81
https://doi.org/10.1534/genetics.112.142570
https://doi.org/10.1534/genetics.112.142570
Publikováno v:
Genetics. 184:1077-1094
Tandem duplications are among the most common mutation events. The high loss rate of duplication suggested that the frequency of duplications in a bacterial population (1/1000) might reflect a steady state dictated by relative rates of formation (kF)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa5cf7bfe8a182f6f4b10f55f0c84305
https://doi.org/10.1534/genetics.109.111963
https://doi.org/10.1534/genetics.109.111963
Publikováno v:
Proceedings of the National Academy of Sciences. 103:17319-17324
In a phenomenon referred to as “adaptive mutation,” a population of bacterial cells with a mutation in the lac operon ( lac − ) accumulates Lac + revertants during prolonged exposure to selective growth conditions (lactose). Evidence was provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16bfb67b99420f99ae2c3032678e11bb
https://doi.org/10.1073/pnas.0608309103
https://doi.org/10.1073/pnas.0608309103
Publikováno v:
Journal of Bacteriology. 186:7635-7644
Adenosylcobalamin (Ado-B 12 ) is both the cofactor and inducer of ethanolamine ammonia lyase (EA-lyase), a catabolic enzyme for ethanolamine. De novo synthesis of Ado-B 12 by Salmonella enterica occurs only under anaerobic conditions. Therefore, aero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced3d8d06e055d37280155221b61b929
https://doi.org/10.1128/jb.186.22.7635-7644.2004
https://doi.org/10.1128/jb.186.22.7635-7644.2004
Autor:
John R. Roth, Eric Kofoid, Dan I. Andersson, Kim L. Bunny, Elisabeth Kugelberg, E. Susan Slechta
Publikováno v:
Proceedings of the National Academy of Sciences. 100:12847-12852
In a particular genetic system, selection stimulates reversion of a lac mutation and causes genome-wide mutagenesis (adaptive mutation). Selection allows rare plated cells with a duplication of the leaky lac allele to initiate clones within which fur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5206119509eb6894a15aa86a1784aae
https://doi.org/10.1073/pnas.1735464100
https://doi.org/10.1073/pnas.1735464100
Publikováno v:
Journal of Bacteriology. 185:660-663
Plasmid F′ 128 was formed by an exchange between chromosomal Rep sequences that placed lac near dinB between many pairs of Rep sequences. Plasmid F′ 128 is critical for selection-enhanced lac reversion (adaptive mutation), which requires prior la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f34d85ae65b0360b11caf588bd66f6
https://doi.org/10.1128/jb.185.2.660-663.2003
https://doi.org/10.1128/jb.185.2.660-663.2003
Publikováno v:
Scopus-Elsevier
The eut operon of Salmonella typhimurium encodes proteins involved in the cobalamin-dependent degradation of ethanolamine. Previous genetic analysis revealed six eut genes that are needed for aerobic use of ethanolamine; one ( eutR ), encodes a posit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08c8b9ada4d513e2ba6d15262b4de52
https://doi.org/10.1128/jb.181.17.5317-5329.1999
https://doi.org/10.1128/jb.181.17.5317-5329.1999
Publikováno v:
Genetics, vol 196, iss 1
Tandem genetic duplications arise frequently between the seven directly repeated 5.5-kb rrn loci that encode ribosomal RNAs in Salmonella enterica. The closest rrn genes, rrnB and rrnE, flank a 40-kb region that includes the purHD operon. Duplication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec6b7ebad3e6652bdd86fa33f5e59be
https://europepmc.org/articles/PMC3872179/
https://europepmc.org/articles/PMC3872179/
