Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Eric Juskewitz"'
Autor:
Philip Rainsford, Fredrik G. Rylandsholm, Martin Jakubec, Mitchell Silk, Eric Juskewitz, Johanna U. Ericson, John-Sigurd Svendsen, Richard A. Engh, Johan Isaksson
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract One strategy to combat antimicrobial resistance is the discovery of new classes of antibiotics. Most antibiotics will at some point interact with the bacterial membrane to either interfere with its integrity or to cross it. Reliable and effi
Externí odkaz:
https://doaj.org/article/22478ba3ecd247d3aa00bf5fb7815e9d
Autor:
Martin Jakubec, Fredrik G. Rylandsholm, Philip Rainsford, Mitchell Silk, Maxim Bril’kov, Tone Kristoffersen, Eric Juskewitz, Johanna U. Ericson, John Sigurd M. Svendsen
Publikováno v:
Biomolecules, Vol 13, Iss 7, p 1155 (2023)
Antimicrobial peptides (AMPs) are generally membrane-active compounds that physically disrupt bacterial membranes. Despite extensive research, the precise mode of action of AMPs is still a topic of great debate. This work demonstrates that the initia
Externí odkaz:
https://doaj.org/article/c79465dba642485ea21be3f218fd2be1
Autor:
Marte Jenssen, Philip Rainsford, Eric Juskewitz, Jeanette H. Andersen, Espen H. Hansen, Johan Isaksson, Teppo Rämä, Kine Ø. Hansen
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The emergence of drug-resistant bacteria is increasing rapidly in all parts of the world, and the need for new antibiotics is urgent. In our continuous search for new antimicrobial molecules from under-investigated Arctic marine microorganisms, a mar
Externí odkaz:
https://doaj.org/article/b5a8b2dbd1bd445ca40f1a389ad385f5
Autor:
Eric Juskewitz, Ekaterina Mishchenko, Vishesh K. Dubey, Marte Jenssen, Martin Jakubec, Philip Rainsford, Johan Isaksson, Jeanette H. Andersen, Johanna U. Ericson
Publikováno v:
Marine Drugs, Vol 20, Iss 5, p 277 (2022)
Treatment options for infections caused by antimicrobial-resistant bacteria are rendered ineffective, and drug alternatives are needed—either from new chemical classes or drugs with new modes of action. Historically, natural products have been impo
Externí odkaz:
https://doaj.org/article/c0cc8d799d594cc999f72a2e88a51b66
Autor:
Eskil André Karlsen, Wenche Stensen, Eric Juskewitz, Johan Svenson, Mattias Berglin, John Sigurd Mjøen Svendsen
Publikováno v:
Antibiotics, Vol 10, Iss 12, p 1516 (2021)
Medical devices with an effective anti-colonization surface are important tools for combatting healthcare-associated infections. Here, we investigated the anti-colonization efficacy of antimicrobial peptides covalently attached to a gold model surfac
Externí odkaz:
https://doaj.org/article/fef7aea895c54d249e5aa4cf20e0511d
Autor:
Johan Isaksson, Philip Rainsford, Fredrik G. Rylandsholm, Martin Jakubec, Mitchell Silk, Eric Juskewitz, Johanna U. Ericson, John Sigurd Svendsen, Richard A. Engh
One strategy to combat antimicrobial resistance is the discovery of new classes of antibiotics. Most antibiotics will at some point interact with the bacterial membrane to either interfere with its integrity or to cross it. Reliable and efficient too
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef9b5880fbdd52020ea62cf292dcaff9
https://doi.org/10.21203/rs.3.rs-2885575/v1
https://doi.org/10.21203/rs.3.rs-2885575/v1
Autor:
Philip Rainsford, Fredrik Rylandsholm, Martin Jakubec, Eric Juskewitz, Mitchell Silk, Richard A. Engh, Johan Isaksson
Antimicrobial peptides (AMPs) are a promising source of inspiration for new antibiotics discovery, in part because they believed to not trigger rapid resistance development since AMPs have co-existed with bacteria throughout evolution and do not targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe1c332d5adc55e8507a696ee05762a
https://doi.org/10.26434/chemrxiv-2022-hpf6f
https://doi.org/10.26434/chemrxiv-2022-hpf6f
Autor:
Dominik Ausbacher, Trude Anderssen, Glenn R. Morello, Hans-Matti Blencke, Manuel K Langer, Eric Juskewitz, Morten B. Strøm, Tor Haug, Laura Liikanen, Annette Bayer, Johan Isaksson, Marianne Hagensen Paulsen, Magnus Engqvist
Publikováno v:
Journal of medicinal chemistry. 64(15)
We report a series of synthetic cationic amphipathic barbiturates inspired by the pharmacophore model of small antimicrobial peptides (AMPs) and the marine antimicrobials eusynstyelamides. These N,N'-dialkylated-5,5-disubstituted barbiturates consist
Publikováno v:
Nature.
The three of us took a break from our PhD programmes for a stint that enriched our CVs and improved our chances of career success. The three of us took a break from our PhD programmes for a stint that enriched our CVs and improved our chances of care
Publikováno v:
European journal of immunology. 44(8)