Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eric Jacobi"'
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-20 (2018)
Abstract Amyloid beta (Aβ)-mediated synapse dysfunction and spine loss are considered to be early events in Alzheimer’s disease (AD) pathogenesis. N-methyl-D-aspartate receptors (NMDARs) have previously been suggested to play a role for Amyloid be
Externí odkaz:
https://doaj.org/article/ca16cadee91547678309f047b42f3ecb
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6298 (2021)
Onset and progression of Alzheimer’s disease (AD) pathophysiology differs between brain regions. The neocortex, for example, is a brain region that is affected very early during AD. NMDA receptors (NMDARs) are involved in mediating amyloid beta (A
Externí odkaz:
https://doaj.org/article/22b89191162c4c36afa295ddb09d16ef
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 12
International Journal of Molecular Sciences, Vol 22, Iss 6298, p 6298 (2021)
Volume 22
Issue 12
International Journal of Molecular Sciences, Vol 22, Iss 6298, p 6298 (2021)
Onset and progression of Alzheimer’s disease (AD) pathophysiology differs between brain regions. The neocortex, for example, is a brain region that is affected very early during AD. NMDA receptors (NMDARs) are involved in mediating amyloid beta (A
Autor:
Eric Jacobi, Jakob von Engelhardt
AMPA-type glutamate receptors (AMPARs) are key molecules of neuronal communication in our brain. The discovery of AMPAR auxiliary subunits, such as proteins of the TARP, CKAMP and CNIH families, fundamentally changed our understanding of how AMPAR fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047e024c7db7cb0aadefacb02fc0c881
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-20 (2018)
Acta Neuropathologica Communications
Acta Neuropathologica Communications 6(1), 110 (2018). doi:10.1186/s40478-018-0611-4
Acta Neuropathologica Communications
Acta Neuropathologica Communications 6(1), 110 (2018). doi:10.1186/s40478-018-0611-4
Amyloid beta (Aβ)-mediated synapse dysfunction and spine loss are considered to be early events in Alzheimer’s disease (AD) pathogenesis. N-methyl-D-aspartate receptors (NMDARs) have previously been suggested to play a role for Amyloid beta (Aβ)
Autor:
Alexandru Rusu, Ling Zhang, Jakob von Engelhardt, Paul Farrow, Anton Schulmann, Konstantin Khodosevich, Eric Jacobi, Rolf Sprengel, Hannah Monyer
Publikováno v:
Neuron 83(3), 601-615 (2014). doi:10.1016/j.neuron.2014.07.004
Neuron
Neuron
Summary Gating properties and surface trafficking of AMPA receptors (AMPARs) are modulated by auxiliary subunits. Here we studied the function of coexpressed auxiliary subunits belonging to two different classes. We focused on TARP γ-8 and CKAMP44 i
Autor:
Eric Jacobi, Jakob von Engelhardt
Publikováno v:
Current opinion in neurobiology. 45
AMPA receptor (AMPAR) complexes comprise four of the AMPAR subunits GluA1-4 and several additional interacting proteins. Subunit composition determines AMPAR function. However, AMPAR function depends to a large extent also on interacting proteins, wh
Autor:
Livio Oboti, Frank Zufall, Pablo Chamero, Eric Jacobi, Trese Leinders-Zufall, Matthieu Keller, Anabel Pérez-Gómez, Lutz Birnbaumer
Publikováno v:
Chemical Senses
24. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO)
24. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Sep 2014, Dijon, France
BMC Biology
BMC Biology, BioMed Central, 2014, 12 (1), pp.1-17. ⟨10.1186/1741-7007-12-31⟩
BMC Biology 1 (12), 1-17. (2014)
Publons
BMC biology 12(1), 31 (2014). doi:10.1186/1741-7007-12-31
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
24. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO)
24. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Sep 2014, Dijon, France
BMC Biology
BMC Biology, BioMed Central, 2014, 12 (1), pp.1-17. ⟨10.1186/1741-7007-12-31⟩
BMC Biology 1 (12), 1-17. (2014)
Publons
BMC biology 12(1), 31 (2014). doi:10.1186/1741-7007-12-31
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Optimal reproductive fitness is essential for the biological success and survival of species. The vomeronasal organ is strongly implicated in the display of sexual and reproductive behaviors in female mice, yet the roles that apical and basal vomeron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af421c0890fb41f991ce66b3640c9e4
https://hal.inrae.fr/hal-02741642
https://hal.inrae.fr/hal-02741642
Autor:
Eric Jacobi, Charles A. Greer, Jan Weiss, Philippe Zizzari, Samuel J. Gossage, Trese Leinders-Zufall, Bernd Bufe, Bernhard Schick, Frank Zufall, Martina Pyrski, John N. Wood, Vivienne Willnecker, C. Geoffrey Woods
Publikováno v:
Nature. 472(7342)
Loss of function of the gene SCN9A, encoding the voltage-gated sodium channel Na(v)1.7, causes a congenital inability to experience pain in humans. Here we show that Na(v)1.7 is not only necessary for pain sensation but is also an essential requireme