Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Eric J. Stoner"'
Publikováno v:
e-EROS Encyclopedia of Reagents for Organic Synthesis
[7775-41-9] AgF (MW 126.87) InChI = 1S/Ag.FH/h;1H/q+1;/p-1 InChIKey = REYHXKZHIMGNSE-UHFFFAOYSA-M (fluorinating agent1) Physical Data: mp 435 °C; bp 1150 °C; d 5.852 g cm−3. Solubility: highly sol water (182 g/100 g H2O), anhydrous hydrogen fluor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33f175192a1692efa52533bc62d59354
https://doi.org/10.1002/047084289x.rs016.pub2
https://doi.org/10.1002/047084289x.rs016.pub2
Autor:
Elaine C. Lee, Eric J. Stoner, Matthew J. Peterson, Jason S. Tedrow, Alan Christesen, Anthony R. Haight, Prasad S. Raje, Seble H. Wagaw, Margaret C. Hsu, Kenneth M. Engstrom, David M. Barnes, Daniel J. Plata
Publikováno v:
Organic Process Research & Development. 10:803-807
The total synthesis of quinolone antibiotic ABT-492 has been achieved in 67% yield over nine steps from 2,4,5-trifluorobenzoic acid. The highlights of this synthesis include a novel chemoselective chlorination at the 8-position of a highly elaborated
Autor:
M. Robert Leanna, Eric J. Stoner, Maureen A. McLaughlin, Steven L. Condon, Steven A. King, Francis A. J. Kerdesky, Steven J. Wittenberger, Matthew J. Peterson, Michael Rasmussen, Daniel J. Plata
Publikováno v:
Tetrahedron. 60:10171-10180
A practical and efficient synthesis of ketolide antibiotic cethromycin (ABT-773) (1) is described. An effective protection strategy allows high yielding, regioselective C6-O-alkylation and subsequent stereoselective modification of the erythromycin n
Autor:
Eric W. Kristensen, Eric J. Stoner, Gregory M. Brill, Alan Christesen, Casey Chun Zhou, Kent D. Stewart, Edmund D. Matayoshi, Steven J. Wittenberger, L. Steven Hollis, Ronald R. Rasmussen
Publikováno v:
Tetrahedron. 60:10611-10618
Oritavancin is a semi-synthetic glycopeptide antibiotic which is structurally related to vancomycin. When oritavancin bisphosphate is dried in vacuo with heat, a new compound forms. This new compound is stable only in the solid state and reverts to o
Autor:
Anthony R. Haight, John Demattei, Michael Rasmussen, M. Robert Leanna, Daniel J. Plata, Michael S. Allen, Subhash R. Patel, Eric J. Stoner, Matthew J. Peterson, Ramiya H. Premchandran
Publikováno v:
The Journal of Organic Chemistry. 68:8847-8852
Functionalized erythromycin 9-oxime derivatives are 6-O-allylated under mild conditions using substituted allyl tert-butyl carbonates under palladium(0) catalysis. This allylation works well where traditional ether-forming protocols function poorly.
Autor:
Patel Ketan M, Jien-Heh J. Tien, Lawrence Kolaczkowski, Joseph B. Paterson, Arthur J. Cooper, and Peter J. Stengel, Jih-Hua Liu, Daniel J. Plata, Patricia A. Oliver-Shaffer, David A. Riley, Daniel A. Dickman, H. L. Sham, Eric J. Stoner, John E. Lallaman
Publikováno v:
Organic Process Research & Development. 4:264-269
A large scale process for the synthesis of HIV protease inhibitor candidate ABT-378 has been developed which utilizes an intermediate common to the synthesis of ritonavir, Abbott's first generation compound. The synthesis relies on the sequential acy
Publikováno v:
Organic Process Research & Development. 3:145-148
An alternative to carbodiimide-mediated peptide coupling protocols has been developed for a carboxylic acid prone to decomposition by polymerization. This method, involving the in situ generation of an acyl imidazolide, has been applied to the prepar
Publikováno v:
Tetrahedron Letters. 38:4981-4984
Aryl-substituted propargylic N-hydroxyreas cyclize in the presence of catalytic Pd(OAc)2 to yield 2,3-dihydroisoxazoles.
Publikováno v:
e-EROS Encyclopedia of Reagents for Organic Synthesis
[726-42-1] C15H14N2 (MW 222.31) InChI = 1S/C15H14N2/c1-12-3-7-14(8-4-12)16-11-17-15-9-5-13(2)6-10-15/h3-10H,1-2H3 InChIKey = BOSWPVRACYJBSJ-UHFFFAOYSA-N (synthesis of nitrogen heterocycles) Physical Data: bp 221–223 °C/20 mmHg, 114 °C/0.02 mmHg;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16af819e56a142d1af10f3199babf359
https://doi.org/10.1002/047084289x.rd474.pub2
https://doi.org/10.1002/047084289x.rd474.pub2
Publikováno v:
Tetrahedron. 51:11043-11062
A method has been developed which allows for the large scale preparation of biarylmethanes This method involves the initial formation of biarylmethanols via reaction of aryl Grignards with carbonyl compounds followed by a subsequent reduction with io