Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Eric J. Hill"'
Autor:
Itzy E. Morales Pantoja, Lena Smirnova, Alysson R. Muotri, Karl J. Wahlin, Jeffrey Kahn, J. Lomax Boyd, David H. Gracias, Timothy D. Harris, Tzahi Cohen-Karni, Brian S. Caffo, Alexander S. Szalay, Fang Han, Donald J. Zack, Ralph Etienne-Cummings, Akwasi Akwaboah, July Carolina Romero, Dowlette-Mary Alam El Din, Jesse D. Plotkin, Barton L. Paulhamus, Erik C. Johnson, Frederic Gilbert, J. Lowry Curley, Ben Cappiello, Jens C. Schwamborn, Eric J. Hill, Paul Roach, Daniel Tornero, Caroline Krall, Rheinallt Parri, Fenna Sillé, Andre Levchenko, Rabih E. Jabbour, Brett J. Kagan, Cynthia A. Berlinicke, Qi Huang, Alexandra Maertens, Kathrin Herrmann, Katya Tsaioun, Raha Dastgheyb, Christa Whelan Habela, Joshua T. Vogelstein, Thomas Hartung
Publikováno v:
Frontiers in Artificial Intelligence, Vol 6 (2023)
The brain is arguably the most powerful computation system known. It is extremely efficient in processing large amounts of information and can discern signals from noise, adapt, and filter faulty information all while running on only 20 watts of powe
Externí odkaz:
https://doaj.org/article/aebc0f0cd878418ebed9205a612b1932
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Much of the early research into AD relies on a neuron-centric view of the brain, however, evidence of multiple altered cellular interactions between glial cells and the vasculature early in AD has been demonstrated. As such, alterations in astrocyte
Externí odkaz:
https://doaj.org/article/92068887c83f4850a6d8e3980cc8aaa9
Autor:
John B. Butcher, Robert E. Sims, Neville M. Ngum, Amjad H. Bazzari, Stuart I. Jenkins, Marianne King, Eric J. Hill, David A. Nagel, Kevin Fox, H. Rheinallt Parri, Stanislaw Glazewski
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Changes to sensory experience result in plasticity of synapses in the cortex. This experience-dependent plasticity (EDP) is a fundamental property of the brain. Yet, while much is known about neuronal roles in EDP, very little is known about the role
Externí odkaz:
https://doaj.org/article/edf2e7f467bd4acea65c5f1df397e466
Autor:
Alexandra Iordachescu, Erik A. B. Hughes, Stephan Joseph, Eric J. Hill, Liam M. Grover, Anthony D. Metcalfe
Publikováno v:
npj Microgravity, Vol 7, Iss 1, Pp 1-21 (2021)
Abstract Bone is a highly responsive organ, which continuously adapts to the environment it is subjected to in order to withstand metabolic demands. These events are difficult to study in this particular tissue in vivo, due to its rigid, mineralised
Externí odkaz:
https://doaj.org/article/92d0f1bac35a4b89b446ed691ff37888
Autor:
Karan S. Rana, Chathyan Pararasa, Islam Afzal, David A. Nagel, Eric J. Hill, Clifford J. Bailey, Helen R. Griffiths, Ioannis Kyrou, Harpal S. Randeva, Srikanth Bellary, James E. Brown
Publikováno v:
Cardiovascular Diabetology, Vol 16, Iss 1, Pp 1-10 (2017)
Abstract Background Irisin is a hormone released mainly from skeletal muscle after exercise which increases adipose tissue energy expenditure. Adipocytes can also release irisin after exercise, acting as a local adipokine to induce white adipose tiss
Externí odkaz:
https://doaj.org/article/e626261403d449039ec4d9ef647cd052
Autor:
Thomas K. Karikari, David A. Nagel, Alastair Grainger, Charlotte Clarke-Bland, James Crowe, Eric J. Hill, Kevin G. Moffat
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
The inter-cellular propagation of tau aggregates in several neurodegenerative diseases involves, in part, recurring cycles of extracellular tau uptake, initiation of endogenous tau aggregation, and extracellular release of at least part of this prote
Externí odkaz:
https://doaj.org/article/13e6659807bd4a86a1a81109953159b6
Autor:
Alastair I. Grainger, Marianne C. King, David A. Nagel, H. Rheinallt Parri, Michael D. Coleman, Eric J. Hill
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
The brain is the most complex organ in the body, controlling our highest functions, as well as regulating myriad processes which incorporate the entire physiological system. The effects of prospective therapeutic entities on the brain and central ner
Externí odkaz:
https://doaj.org/article/3d308861edbf4efeb4f5125aca345178
Autor:
Thomas Hartung, Lena Smirnova, Itzy E. Morales Pantoja, Akwasi Akwaboah, Dowlette-Mary Alam El Din, Cynthia A. Berlinicke, J. Lomax Boyd, Brian S. Caffo, Ben Cappiello, Tzahi Cohen-Karni, J. Lowry Curley, Ralph Etienne-Cummings, Raha Dastgheyb, David H. Gracias, Frederic Gilbert, Christa Whelan Habela, Fang Han, Timothy D. Harris, Kathrin Herrmann, Eric J. Hill, Qi Huang, Rabih E. Jabbour, Erik C. Johnson, Brett J. Kagan, Caroline Krall, Andre Levchenko, Paul Locke, Alexandra Maertens, Monica Metea, Alysson R. Muotri, Rheinallt Parri, Barton L. Paulhamus, Jesse D. Plotkin, Paul Roach, July Carolina Romero, Jens C. Schwamborn, Fenna Sillé, Alexander S. Szalay, Katya Tsaioun, Daniel Tornero, Joshua T. Vogelstein, Karl J. Wahlin, Donald J. Zack
Publikováno v:
Frontiers in Science. 1
We, the participants of the First Organoid Intelligence Workshop - "Forming an OI Community" (22-24 February 2022), call on the international scientific community to explore the potential of human brain-based organoid cell cultures to advance our und
Autor:
Cyril Besnard, Zhanfeng Cui, Chia-Chen Hsu, Alexander M. Korsunsky, Julian H. George, Eric J. Hill, Sharlayne Waller, Michael D. Coleman, David A. Nagel, Hua Ye
Publikováno v:
Bioactive Materials, Vol 9, Iss, Pp 358-372 (2022)
Bioactive Materials
Bioactive Materials
To reflect human development, it is critical to create a substrate that can support long-term cell survival, differentiation, and maturation. Hydrogels are promising materials for 3D cultures. However, a bulk structure consisting of dense polymer net
Publikováno v:
Emerging Topics in Life Sciences
With the increasing prevalence of neurodegenerative diseases, improved models of the central nervous system (CNS) will improve our understanding of neurophysiology and pathogenesis, whilst enabling exploration of novel therapeutics. Studies of brain