Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Eric J. Charles"'
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 15 (2021)
Background We previously demonstrated that ischemically injured cardiomyocytes release cell‐free DNA and HMGB1 (high mobility group box 1 protein) into circulation during reperfusion, activating proinflammatory responses and ultimately exacerbating
Externí odkaz:
https://doaj.org/article/37f4f02df5fa45bfbee18b24a7f4c0f7
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Imaging holds an important role in the diagnosis of lung diseases. Along with clinical tests, noninvasive imaging techniques provide complementary and valuable information that enables a complete differential diagnosis. Various novel molecul
Externí odkaz:
https://doaj.org/article/adf3aea10c234edcb5e6c640ea3b0f60
Autor:
Aimee Y. Zhang, Katherine M. Marsh, Radhika Rastogi, Di Wu, Eric J. Charles, Irving L. Kron, Robert G. Sawyer, Zequan Yang
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9828 (2021)
Global hypothermia prolongs survival in rats with intraabdominal feculent sepsis by inhibiting inflammatory responses. We hypothesized that topical neck cooling (TNC) has similar benefits. Septic shock was induced by cecal ligation and incision (CLI)
Externí odkaz:
https://doaj.org/article/2a1ba2dd527240e1aea9c2829660f76b
Autor:
Eric J. Charles, MD, PhD, J. Hunter Mehaffey, MD, MSc, Mary E. Huerter, MD, Ashish K. Sharma, PhD, Mark H. Stoler, MD, Mark E. Roeser, MD, Dustin M. Walters, MD, Curtis G. Tribble, MD, Irving L. Kron, MD, Victor E. Laubach, PhD
Publikováno v:
Transplantation Direct, Vol 4, Iss 12, p e405 (2018)
Background. Increased utilization of donation after circulatory death (DCD) lungs may help alleviate the supply/demand mismatch between available donor organs and lung transplant candidates. Using an established porcine DCD model, we sought to determ
Externí odkaz:
https://doaj.org/article/51671e5f44e14dfea2b48e1ff42bfc59
Autor:
Zdravka Daneva, Victor E. Laubach, Sean W. Noona, Aimee Zhang, Eric J. Charles, Huy Q. Ta, Evan P. Rotar, Morgan Salmon, Nathan Haywood, Swapnil K. Sonkusare
Publikováno v:
Ann Thorac Surg
BACKGROUND: Lung ischemia-reperfusion injury (IRI), involving severe inflammation and edema, is a major cause of primary graft dysfunction following transplant. Activation of transient receptor potential vanilloid 4 (TRPV4) channels modulates vascula
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 163:1431-1434
Autor:
J. Hunter Mehaffey, William Z. Chancellor, Mark H. Stoler, Eric J. Charles, Dustin T. Money, Aimee Zhang, Matthew R. Byler, Victor E. Laubach, Nathan Haywood, Mark E. Roeser, Irving L. Kron, Jared P. Beller, Huy Q. Ta
Publikováno v:
Seminars in Thoracic and Cardiovascular Surgery. 34:337-346
Sepsis is the leading cause of acute respiratory distress syndrome (ARDS) in adults and carries a high mortality. Utilizing a previously validated porcine model of sepsis-induced ARDS, we sought to refine our novel therapeutic technique of in vivo lu
Publikováno v:
Surgery. 170:1495-1500
Background There is a strong association between socioeconomic status and surgical outcomes; however, the optimal method for socioeconomic risk-stratification remains elusive. We aimed to compare 2 metrics of socioeconomic ranking by ZIP code, the Di
Autor:
Mohammed A. Quader, Eric J. Charles, J. Hunter Mehaffey, Robert B. Hawkins, Gorav Ailawadi, Alan M. Speir, Nicholas R. Teman
Publikováno v:
The Annals of Thoracic Surgery. 111:1478-1484
Background Limited multi-institutional data evaluating minimally invasive cardiac surgery (MICS) coronary artery bypass surgery (CABG) outcomes have raised concern for increased resource utilization compared with standard sternotomy. The purpose of t
Autor:
Raymond J. Strobel, Eric J. Charles, J. Hunter Mehaffey, Robert B. Hawkins, Mohammed A. Quader, Jeffrey B. Rich, Alan M. Speir, Gorav Ailawadi
Publikováno v:
Seminars in thoracic and cardiovascular surgery.
Infective endocarditis affects patients of all socioeconomic status. We hypothesized that the Distressed Communities Index (DCI), a comprehensive assessment of socioeconomic status, would be associated with risk-adjusted mortality for patients with e