Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Eric J. Bonventre"'
Autor:
Gregory T. Robertson, Qun Du, Timothy B Doyle, Eric J. Bonventre, Timothy W. Morris, Leonard R. Duncan, Dalai Yan, A. Simon Lynch, Eric D. Roche
Publikováno v:
Antimicrobial agents and chemotherapy. 52(7)
Rifamycins have proven efficacy in the treatment of persistent bacterial infections. However, the frequency with which bacteria develop resistance to rifamycin agents restricts their clinical use to antibiotic combination regimens. In a program direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e5410181fac5a2006219dc55f11601
https://pubmed.ncbi.nlm.nih.gov/18443108
https://pubmed.ncbi.nlm.nih.gov/18443108
Autor:
Qun Du, Timothy B Doyle, Eric J. Bonventre, Timothy W. Morris, Leonard R. Duncan, Dalai Yan, A. Simon Lynch, Gregory T. Robertson, Eric D. Roche
We present data from antimicrobial assays performed in vitro that pertain to the potential clinical utility of a novel rifamycin-quinolone hybrid antibiotic, CBR-2092, for the treatment of infections mediated by gram-positive cocci. The MIC 90 s for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b12cb50cda0d4329286bec583bdbfb
https://europepmc.org/articles/PMC2443883/
https://europepmc.org/articles/PMC2443883/
Autor:
Eric D. Roche, Dalai Yan, Eric J. Bonventre, Anthony Simon Lynch, Timothy B Doyle, Daniel Denton, Gregory T. Robertson, Keith D. Combrink, Katrina Chapo, Susan Harran, Zhenkun Ma
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(2)
A novel series of 3-morpholino rifamycins in which the C25 acetate group was replaced by a carbamate group were prepared and found to exhibit significantly improved antimicrobial activity than rifampin against Mycobacterium smegmatis. Further charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9591c1db99dba907e8cdc77e9f9a953
https://pubmed.ncbi.nlm.nih.gov/17070048
https://pubmed.ncbi.nlm.nih.gov/17070048