Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eric J Wallenstein"'
Autor:
Nicholas Murgolo, Zhimei Du, Robin S Ehrick, Jason D. Hughes, Guanghua Benson Li, Nihal Tugcu, Richard C. Stevens, Eric J Wallenstein, Jia Zhao, Jorge Quiroz, Matthew Manahan, Ren Liu, Yung-Shyeng Tsao, David Pollard, Jennifer M. Pollard, Michael C Nelson
Publikováno v:
Biotechnology progressREFERENCES. 38(1)
In recent years, assurance of clonality of the production cell line has been emphasized by health authorities during review of regulatory submissions. When insufficient assurance of clonality is provided, augmented control strategies may be required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad30f0dcf2ecf8f441813bca0f6ba820
https://pubmed.ncbi.nlm.nih.gov/34586757
https://pubmed.ncbi.nlm.nih.gov/34586757
Autor:
null Guanghua Benson Li, null Jennifer Pollard, null Ren Liu, null Richard C. Stevens, null Jorge Quiroz, null Michael C. Nelson, null Matthew Manahan, null Nicholas Murgolo, null Robin S. Ehrick, null Eric J. Wallenstein, null Jason Hughes, null Yung‐shyeng Tsao, null Jia Zhao, null Zhimei Du, null Nihal Tugcu, null David Pollard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::332b821dd7adfa6023cfbd26752ab65a
https://doi.org/10.1002/btpr.3215/v2/response1
https://doi.org/10.1002/btpr.3215/v2/response1
Publikováno v:
Biotechnology Progress. 26:1714-1723
Control of genetic expression is a critical issue in the field of stem cell biology, where determining a cell fate or reprogramming adult somatic cells into pluripotent cells has become a common experimental practice. In turn, for these cells to have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813f1a4fff233e001747795da130486f
https://doi.org/10.1002/btpr.472
https://doi.org/10.1002/btpr.472
Publikováno v:
Biotechnology and Bioengineering. 101:859-872
There is a critical need for new sources of hepatocytes, both clinically to provide support for patients with liver failure and in drug discovery for toxicity, metabolic and pharmacokinetic screening of new drug entities. We have reported previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff9d714533f9ee4d8e03f12dfa768ef
https://doi.org/10.1002/bit.22027
https://doi.org/10.1002/bit.22027
Autor:
Rene S. Schloss, Jeffery Barminko, Tim Maguire, Martin L. Yarmush, Nripen Sharma, Eric Novik, Eric J. Wallenstein
Publikováno v:
Biotechnology Progress. 24:1132-1141
The development of implantable engineered liver tissue constructs and ex vivo hepatocyte-based therapeutic devices are limited by an inadequate hepatocyte cell source. In our previous studies, embryoid body (EB)-mediated stem cell differentiation spo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0552b8cb787078f77a0b01d15632cf74
https://doi.org/10.1002/btpr.41
https://doi.org/10.1002/btpr.41
Autor:
Daniel Fife, Eric J. Wallenstein
Publikováno v:
Drug Safety. 24:233-237
Objectives: Determine whether recent US adverse event reports for several nonsteroidal anti-inflammatory drugs (NSAIDs) conform to the temporal pattern observed by Dr JCP Weber in the UK in the early 1980s, i.e. a rising count in the first few years
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785d1bc26748e15eb87278b8532bf460
https://doi.org/10.2165/00002018-200124030-00006
https://doi.org/10.2165/00002018-200124030-00006
Autor:
Tim Maguire, Eric J. Wallenstein, Eric Novik, Nripen Sharma, Martin L. Yarmush, Rene S. Schloss
Publikováno v:
Tissue engineering. Part C, Methods. 15(2)
The generation of a large number of fully functional hepatocytes from a renewable cell source can provide an unlimited resource for bioartificial liver devices and cell replacement therapies. We have established a directed differentiation system usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815fbb79b6aa5a785842a6ee33e007e1
https://pubmed.ncbi.nlm.nih.gov/19196121
https://pubmed.ncbi.nlm.nih.gov/19196121
Autor:
Rene S. Schloss, Ioannis P. Androulakis, Nripen Sharma, Alexander E. Davidovich, Henrik Pedersen, Martin L. Yarmush, Tim Maguire, Eric Novik, Eric J. Wallenstein
Publikováno v:
Biotechnology and bioengineering. 98(3)
Integral to the development of embryonic stem cell therapeutic strategies for hepatic disorders is the iden- tification and establishment of a controllable hepatic differ- entiation strategy. In order to address this issue we have established an algi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc21ae1872b710648a12d058d10bb889
https://pubmed.ncbi.nlm.nih.gov/17390383
https://pubmed.ncbi.nlm.nih.gov/17390383
Publikováno v:
Proceedings of the IEEE 31st Annual Northeast Bioengineering Conference, 2005..
Although defined differentiation strategies exist for generating hepatocyte-like cells from mouse embryonic stem (ES) cells, these systems yield a heterogeneous end population, from which it is difficult to assay, purify and quantify cells of interes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72bbdc9a5d1ea4acbb0f2dced4f28cea
https://doi.org/10.1109/nebc.2005.1431995
https://doi.org/10.1109/nebc.2005.1431995