Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Eric J Gowans"'
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Externí odkaz:
https://doaj.org/article/e3d236dd5783430f8157dc0c5ff5df58
Autor:
Shuo Li, Stuart Roberts, Magdalena Plebanski, Maelenn Gouillou, Tim Spelman, Philippe Latour, David Jackson, Lorena Brown, Rosemary L Sparrow, H Miles Prince, Derek Hart, Bruce E Loveland, Eric J Gowans
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e39368 (2012)
We have previously reported a world-first phase I clinical trial to treat HCV patients using monocyte-derived dendritic cells (Mo-DC) loaded with HCV-specific lipopeptides. While the brief treatment proved to be safe, it failed to reduce the viral lo
Externí odkaz:
https://doaj.org/article/fe96ac32017b46fab318fc7acca2fd55
Autor:
Shuo Li, Stefan Floess, Alf Hamann, Silvana Gaudieri, Andrew Lucas, Margaret Hellard, Stuart Roberts, Geza Paukovic, Magdalena Plebanski, Bruce E Loveland, Campbell Aitken, Simon Barry, Louis Schofield, Eric J Gowans
Publikováno v:
PLoS Pathogens, Vol 5, Iss 12, p e1000707 (2009)
We reported previously that a proportion of natural CD25(+) cells isolated from the PBMC of HCV patients can further upregulate CD25 expression in response to HCV peptide stimulation in vitro, and proposed that virus-specific regulatory T cells (Treg
Externí odkaz:
https://doaj.org/article/b647f92a4c5a4c48b814381e4af918b7
Autor:
Danushka K. Wijesundara, Arthur Yeow, Christopher L.D. McMillan, Jovin J.Y. Choo, Aleksandra Todorovic, Zelalem A. Mekonnen, Makutiro G. Masavuli, Paul R. Young, Eric J. Gowans, Branka Grubor-Bauk, David A. Muller
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102056- (2023)
Zika virus (ZIKV) infections are spreading silently with limited global surveillance in at least 89 countries and territories. There is a pressing need to develop an effective vaccine suitable for equitable distribution globally. Consequently, we pre
Externí odkaz:
https://doaj.org/article/3a57796828b4448fb11999e2970c3e10
Autor:
Zelalem A. Mekonnen, Makutiro G. Masavuli, Wenbo Yu, Jason Gummow, Dawn M. Whelan, Zahraa Al-Delfi, Joseph Torresi, Eric J. Gowans, Branka Grubor-Bauk
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
A vaccine that induces potent, broad and sustained cell-mediated immunity, resulting in effective memory has the potential to restrict hepatitis C (HCV) virus infection. Early, multi-functional CD4+ and CD8+ T cell responses against non-structural pr
Externí odkaz:
https://doaj.org/article/d3e86a4930cb4bfe96e6a5ef5ee0e629
Autor:
Danushka K. Wijesundara, Wenbo Yu, Ben J. C. Quah, Preethi Eldi, John D. Hayball, Kerrilyn R. Diener, Ilia Voskoboinik, Eric J. Gowans, Branka Grubor-Bauk
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract The use of cost-effective vaccines capable of inducing robust CD8+ T cell immunity will contribute significantly towards the elimination of persistent viral infections and cancers worldwide. We have previously reported that a cytolytic DNA v
Externí odkaz:
https://doaj.org/article/458aba626a294f098ff6f9d7d1461b40
Autor:
Joshua G. Kovoor, Jonathan Henry W. Jacobsen, Joanna Duncan, Afua A. Addo, David R. Tivey, Wendy J. Babidge, David Penn, James Churchill, Trevor G. Collinson, Jen Kok, Shane Kelly, Vicky H. Lu, Vanessa S. Beavis, Andrew D. MacCormick, Brendon J. Kearney, Eric J. Gowans, Peter J. Hewett, Thomas J. Hugh, Henry H. Woo, Robert T. Padbury, David A. Scott, Mark Frydenberg, Guy J. Maddern
Publikováno v:
ANZ journal of surgery. 92(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d981181bb99c3a10568dcb16159eeb1
https://pubmed.ncbi.nlm.nih.gov/35535005
https://pubmed.ncbi.nlm.nih.gov/35535005
Publikováno v:
BioTechniques, Vol 43, Iss 5, Pp 675-681 (2007)
RNA replicons represent potential vaccine delivery vehicles, but are considered too unstable for such use. This study examined the recovery, integrity and function of in vitro transcribed replicon RNA encoding hepatitis C virus (HCV) proteins. To rem
Externí odkaz:
https://doaj.org/article/0076c59a3a2243aabc7664f9603def9e
Autor:
Elizabeth Vincan, Linda Earnest-Silveira, Heidi E. Drummer, Branka Grubor-Bauk, Irene Boo, Danushka K. Wijesundara, Joseph Torresi, Eric J. Gowans, Dale Christiansen, Paul A. Ramsland
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
The introduction of directly acting antiviral agents (DAAs) has produced significant improvements in the ability to cure chronic hepatitis C infection. However, with over 2% of the world’s population infected with HCV, complications arising from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdcdc436062575e134207736d0862f4
http://link.springer.com/article/10.1038/s41598-019-45461-z
http://link.springer.com/article/10.1038/s41598-019-45461-z
Autor:
Danushka K. Wijesundara, Ronald J. Jackson, Eric J. Gowans, Charani Ranasinghe, S. Mahboob, M.I. Jaeson, Zheyi Li, Branka Grubor-Bauk, Sreeja Roy
Publikováno v:
Vaccine. 37:1266-1276
This study demonstrates that route and viral vector can significantly influence the innate lymphoid cells (ILC) and dendritic cells (DC) recruited to the vaccination site, 24 h post delivery. Intranasal (i.n.) vaccination induced ST2/IL-33R+ ILC2, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed9cf8e52167fcc6751244fdccc34eb
https://doi.org/10.1016/j.vaccine.2019.01.045
https://doi.org/10.1016/j.vaccine.2019.01.045