Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Eric J Carlson"'
Autor:
Marjolijn Renard, Laura Muiño-Mosquera, Elise C Manalo, Sara Tufa, Eric J Carlson, Douglas R Keene, Julie De Backer, Lynn Y Sakai
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197631 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0181166.].
Externí odkaz:
https://doaj.org/article/15aa6547e3ca471fa061f4c65cf80ebf
Autor:
Marjolijn Renard, Laura Muiño-Mosquera, Elise C Manalo, Sara Tufa, Eric J Carlson, Douglas R Keene, Julie De Backer, Lynn Y Sakai
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181166 (2017)
Sex-related differences as well as the adverse effect of pregnancy on aortic disease outcome are well-established phenomena in humans with Marfan syndrome (MFS). The underlying mechanisms of these observations are largely unknown.In an initial (pilot
Externí odkaz:
https://doaj.org/article/ed35589b5aca43a79652fc94bfb2d5d2
Autor:
Gerhard Sengle, Valerie Carlberg, Sara F Tufa, Noe L Charbonneau, Silvia Smaldone, Eric J Carlson, Francesco Ramirez, Douglas R Keene, Lynn Y Sakai
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005340 (2015)
Fibrillins are large extracellular macromolecules that polymerize to form the backbone structure of connective tissue microfibrils. Mutations in the gene for fibrillin-1 cause the Marfan syndrome, while mutations in the gene for fibrillin-2 cause Con
Externí odkaz:
https://doaj.org/article/30f76c833401457b9abc1bb3525c63e4
Autor:
Gerhard Sengle, Ko Tsutsui, Douglas R Keene, Sara F Tufa, Eric J Carlson, Noe L Charbonneau, Robert N Ono, Takako Sasaki, Mary K Wirtz, John R Samples, Liselotte I Fessler, John H Fessler, Kiyotoshi Sekiguchi, Susan J Hayflick, Lynn Y Sakai
Publikováno v:
PLoS Genetics, Vol 8, Iss 1, p e1002425 (2012)
Fibrillin-1 is a ubiquitous extracellular matrix molecule that sequesters latent growth factor complexes. A role for fibrillin-1 in specifying tissue microenvironments has not been elucidated, even though the concept that fibrillin-1 provides extrace
Externí odkaz:
https://doaj.org/article/f3d4e5a100c84ffc8be2e4a6ffbeff33
Autor:
Eric J. Carlson, PhD, Megan Rushkin, BA, Derek Darby, BA, Trisha Chau, BS, Renee L. Shirley, PhD, Jeff S. King, PhD, Khanh Nguyen, MD, Gregory J. Landry, MD, Gregory L. Moneta, MD, Cherrie Abraham, MD, Lynn Y. Sakai, PhD, Amir F. Azarbal, MD
Publikováno v:
JVS - Vascular Science, Vol 3, Iss , Pp 389-402 (2022)
Objective: Fragments of fibrillin-1 and fibrillin-2 will be detectable in the plasma of patients with aortic dissections and aneurysms. We sought to determine whether the plasma fibrillin fragment levels (PFFLs) differ between patients with thoracic
Externí odkaz:
https://doaj.org/article/20bfb613e30d45ea8d0537036c340015
Autor:
Eric J. Carlson, Joshua R. Smith
Publikováno v:
IEEE Transactions on Circuits and Systems I: Regular Papers. 70:977-990
Autor:
Eric J. Carlson, Lynn Y. Sakai, Sara F. Tufa, Douglas R. Keene, Valerie M. Carlberg, Elise C. Manalo, Noe L. Charbonneau
Publikováno v:
The Anatomical Record. 303:1590-1603
Immunolocalization studies have shown that fibrillin-1 is distributed ubiquitously in the connective tissue space from early embryonic times through old age. When mutated, the gene for fibrillin-1 (FBN1) causes the Marfan syndrome, a common inherited
Autor:
Kenneth L. Parker, Eric J. Carlson
Richard Greenham was one of the most important and respected figures among the Elizabethan clergy. His contemporaries described him as the founder of a previously unknown pastoral art: the cure of cases of conscience. Despite his fame in the Elizabet
Autor:
Scott A. LeMaire, Joseph S. Coselli, Noe L. Charbonneau, Caryn K. Snyder, Susan J. Hayflick, Lynn Y. Sakai, Lynn M. Marshall, Jean P. O'Malley, Eric J. Carlson
Publikováno v:
Circulation Research. 113:1159-1168
Rationale: Mutations in fibrillin-1 are associated with thoracic aortic aneurysm (TAA) in Marfan syndrome. Genome-wide association studies also implicate fibrillin-1 in sporadic TAA. Fragmentation of the aortic elastic lamellae is characteristic of T