Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Eric J, Devor"'
Autor:
Garima Dixit, Jesus Gonzalez‐Bosquet, Joseph Skurski, Eric J. Devor, Erin B. Dickerson, Warren B. Nothnick, Priya D. Issuree, Kimberly K. Leslie, Thorsten Maretzky
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 5, Pp n/a-n/a (2023)
Abstract Background Mutations in the receptor tyrosine kinase gene fibroblast growth factor receptor 2 (FGFR2) occur at a high frequency in endometrial cancer (EC) and have been linked to advanced and recurrent disease. However, little is known about
Externí odkaz:
https://doaj.org/article/e1ddfbedbc6649e691ed24abee9aaa3f
Autor:
Whitney Cowman, Sabrina M. Scroggins, Wendy S. Hamilton, Alexandra E. Karras, Noelle C. Bowdler, Eric J. Devor, Mark K. Santillan, Donna A. Santillan
Publikováno v:
BMC Pregnancy and Childbirth, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Obesity in pregnancy is common, with more than 50% of pregnant women being overweight or obese. Obesity has been identified as an independent predictor of dysfunctional labor and is associated with increased risk of failed inducti
Externí odkaz:
https://doaj.org/article/637b01f7fe23463a884e7ca8c4fa0c93
Autor:
Jianling Bi, Yuping Zhang, Paige K. Malmrose, Haley A. Losh, Andreea M. Newtson, Eric J. Devor, Kristina W. Thiel, Kimberly K. Leslie
Publikováno v:
Cell Death and Disease, Vol 13, Iss 1, Pp 1-10 (2022)
Abstract Histone deacetylase (HDAC) inhibitors and proteasome inhibitors have been approved by the FDA for the treatment of multiple myeloma and lymphoma, respectively, but have not achieved similar activity as single agents in solid tumors. Preclini
Externí odkaz:
https://doaj.org/article/22755d59f786409eb791c68e2d8e5ad7
Autor:
Jesus Gonzalez-Bosquet, Megan E. McDonald, David P. Bender, Brian J. Smith, Kimberly K. Leslie, Michael J. Goodheart, Eric J. Devor
Publikováno v:
Cancers, Vol 15, Iss 13, p 3316 (2023)
There are strong correlations between the microbiome and human disease, including cancer. However, very little is known about potential mechanisms associated with malignant transformation in microbiome-associated gynecological cancer, except for HPV-
Externí odkaz:
https://doaj.org/article/c7a4299cc6fc4c258794aa967644b034
Autor:
Jesus Gonzalez Bosquet, Eric J. Devor, Andreea M. Newtson, Brian J. Smith, David P. Bender, Michael J. Goodheart, Megan E. McDonald, Terry A. Braun, Kristina W. Thiel, Kimberly K. Leslie
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Nearly a third of patients with high-grade serous ovarian cancer (HGSC) do not respond to initial therapy and have an overall poor prognosis. However, there are no validated tools that accurately predict which patients will not respond. Our
Externí odkaz:
https://doaj.org/article/f68931067a254b7db52a837c8291c2da
Autor:
Jesus Gonzalez-Bosquet, Nicholas D. Cardillo, Henry D. Reyes, Brian J. Smith, Kimberly K. Leslie, David P. Bender, Michael J. Goodheart, Eric J. Devor
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14814 (2022)
The preoperative diagnosis of pelvic masses has been elusive to date. Methods for characterization such as CA-125 have had limited specificity. We hypothesize that genomic variation can be used to create prediction models which accurately distinguish
Externí odkaz:
https://doaj.org/article/f988e12d2edb4b519284a5377718127a
Autor:
Nicholas Cardillo, Eric J. Devor, Silvana Pedra Nobre, Andreea Newtson, Kimberly Leslie, David P. Bender, Brian J. Smith, Michael J. Goodheart, Jesus Gonzalez-Bosquet
Publikováno v:
Cancers, Vol 14, Iss 14, p 3554 (2022)
Advanced high-grade serous (HGSC) ovarian cancer is treated with either primary surgery followed by chemotherapy or neoadjuvant chemotherapy followed by interval surgery. The decision to proceed with surgery primarily or after chemotherapy is based o
Externí odkaz:
https://doaj.org/article/e50f97cf47ae4f9e98796b332357985a
Autor:
Kristina W. Thiel, Eric J. Devor, Virginia L. Filiaci, David Mutch, Katherine Moxley, Angeles Alvarez Secord, Krishnansu S. Tewari, Megan E. McDonald, Cara Mathews, Casey Cosgrove, Summer Dewdney, Carol Aghajanian, Megan I. Samuelson, Heather A. Lankes, Robert A. Soslow, Kimberly K. Leslie
Publikováno v:
Journal of Clinical Oncology. 40:3289-3300
PURPOSE The status of p53 in a tumor can be inferred by next-generation sequencing (NGS) or by immunohistochemistry (IHC). We examined the association between p53 IHC and sequence and whether p53 IHC alone, or integrated with TP53 NGS, predicts the o
Autor:
Eric J. Devor, Brandon M. Schickling, Jace R. Lapierre, David P. Bender, Jesus Gonzalez-Bosquet, Kimberly K. Leslie
Publikováno v:
Pharmaceuticals, Vol 14, Iss 9, p 942 (2021)
Elevated expression of placenta-specific protein 1 (PLAC1) is associated with the increased proliferation and invasiveness of a variety of human cancers, including ovarian cancer. Recent studies have shown that the tumor suppressor p53 directly suppr
Externí odkaz:
https://doaj.org/article/5e27e07441e14791ae4d52403dc2c939
Autor:
Jianling Bi, Garima Dixit, Yuping Zhang, Eric J. Devor, Haley A. Losh, Andreea M. Newtson, Kristen L. Coleman, Donna A. Santillan, Thorsten Maretzky, Kristina W. Thiel, Kimberly K. Leslie
Publikováno v:
Pharmaceuticals, Vol 14, Iss 7, p 682 (2021)
Angiogenesis plays a crucial role in tumor development and metastasis. Both bevacizumab and cediranib have demonstrated activity as single anti-angiogenic agents in endometrial cancer, though subsequent studies of bevacizumab combined with chemothera
Externí odkaz:
https://doaj.org/article/b00a64b6198e48c4b43780cdc49369ac