Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Eric J, Arts"'
Autor:
Alyssa K. Overton, Jennifer J. Knapp, Opeyemi U. Lawal, Richard Gibson, Anastasia A. Fedynak, Adebowale I. Adebiyi, Brittany Maxwell, Lydia Cheng, Carina Bee, Asim Qasim, Kyle Atanas, Mark Payne, Rebecca Stuart, Manon D. Fleury, Natalie C. Knox, Delaney Nash, Yemurayi C. Hungwe, Samran R. Prasla, Hannifer Ho, Simininuoluwa O. Agboola, Su-Hyun Kwon, Shiv Naik, Valeria R. Parreira, Fozia Rizvi, Melinda J. Precious, Steven Thomas, Marcos Zambrano, Vixey Fang, Elaine Gilliland, Monali Varia, Maureen Horn, Chrystal Landgraff, Eric J. Arts, Lawrence Goodridge, Devan Becker, Trevor C. Charles
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has shown wastewater (WW) surveillance to be an effective means of tracking the emergence of viral lineages which arrive by many routes of transmission including via t
Externí odkaz:
https://doaj.org/article/faa1de30d95240a0bf9bf5f529babe33
Autor:
Minh Ha Ngo, Joshua Pankrac, Ryan C. Y. Ho, Emmanuel Ndashimye, Rahul Pawa, Renata Ceccacci, Tsigereda Biru, Abayomi S. Olabode, Katja Klein, Yue Li, Colin Kovacs, Robert Assad, Jeffrey M. Jacobson, David H. Canaday, Stephen Tomusange, Samiri Jamiru, Aggrey Anok, Taddeo Kityamuweesi, Paul Buule, Ronald M. Galiwango, Steven J. Reynolds, Thomas C. Quinn, Andrew D. Redd, Jessica L. Prodger, Jamie F. S. Mann, Eric J. Arts
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
To date, an affordable, effective treatment for an HIV-1 cure remains only a concept with most “latency reversal” agents (LRAs) lacking specificity for the latent HIV-1 reservoir and failing in early clinical trials. We assessed HIV-1 latency rev
Externí odkaz:
https://doaj.org/article/c4e48e2d64a24cd4aecbe0e0f13130b6
Autor:
Ocean Thakali, Élisabeth Mercier, Walaa Eid, Martin Wellman, Julia Brasset-Gorny, Alyssa K. Overton, Jennifer J. Knapp, Douglas Manuel, Trevor C. Charles, Lawrence Goodridge, Eric J. Arts, Art F. Y. Poon, R. Stephen Brown, Tyson E. Graber, Robert Delatolla, Christopher T. DeGroot, Ontario Wastewater Surveillance Consortium
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Wastewater surveillance of coronavirus disease 2019 (COVID-19) commonly applies reverse transcription-quantitative polymerase chain reaction (RT-qPCR) to quantify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA concentration
Externí odkaz:
https://doaj.org/article/bc74bea4a03940bd85b38f29b9ec9203
Autor:
Denis M. Tebit, Gabrielle Nickel, Richard Gibson, Myriam Rodriguez, Nicolas J. Hathaway, Katie Bain, Angel L. Reyes-Rodriguez, Pascal Ondoa, Jonathan L. Heeney, Yue Li, Jennifer Bongorno, David Canaday, David McDonald, Jeffrey A. Bailey, Eric J. Arts
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104965- (2024)
Summary: Background: Simian immunodeficiency viruses (SIV) have been jumping between non-human primates in West/Central Africa for thousands of years and yet, the HIV-1 epidemic only originated from a primate lentivirus over 100 years ago. Methods: T
Externí odkaz:
https://doaj.org/article/2775faec513a4e519cd82b6bb90a918f
Autor:
Hannah O. Ajoge, Tyler M. Renner, Kasandra Bélanger, Matthew Greig, Samar Dankar, Hinissan P. Kohio, Macon D. Coleman, Emmanuel Ndashimye, Eric J. Arts, Marc-André Langlois, Stephen D. Barr
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Antiretroviral APOBEC3 may contribute to HIV-1 latency. In this study, Ajoge and Renner et al. identify a previously undescribed function of human APOBEC3 proteins in redirecting integrations of HIV-1 DNA into more transcriptionally inactive regions
Externí odkaz:
https://doaj.org/article/5d4fac7ee2454ce3a9f9906f54abe8e0
Autor:
Kate A. Parham, Gyoung Nyoun Kim, Connor G. Richer, Marina Ninkov, Kunyu Wu, Nasrin Saeedian, Yue Li, Rasheduzzaman Rashu, Stephen D. Barr, Eric J. Arts, S.M. Mansour Haeryfar, C. Yong Kang, Ryan M. Troyer
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106292- (2023)
Summary: Recombinant vesicular stomatitis virus (rVSV) vaccines expressing spike proteins of Wuhan, Beta, and/or Delta variants of SARS-CoV-2 were generated and tested for induction of antibody and T cell immune responses following intramuscular deli
Externí odkaz:
https://doaj.org/article/6d89fe729e7c44c29e2562f50f8199cf
Autor:
Gyoung Nyoun Kim, Jung-Ah Choi, Kunyu Wu, Nasrin Saeedian, Eunji Yang, Hayan Park, Sun-Je Woo, Gippeum Lim, Seong-Gyu Kim, Su-Kyeong Eo, Hoe Won Jeong, Taewoo Kim, Jae-Hyung Chang, Sang Hwan Seo, Na Hyung Kim, Eunsil Choi, Seungho Choo, Sangkyun Lee, Andrew Winterborn, Yue Li, Kate Parham, Justin M Donovan, Brock Fenton, Jimmy D Dikeakos, Gregory A Dekaban, S M Mansour Haeryfar, Ryan M Troyer, Eric J Arts, Stephen D Barr, Manki Song, C Yong Kang
Publikováno v:
PLoS Pathogens, Vol 18, Iss 11, p e1011000 (2022)
[This corrects the article DOI: 10.1371/journal.ppat.1010092.].
Externí odkaz:
https://doaj.org/article/15f0ff1dc7e44be6a3819f39932b154d
Autor:
Sherazaan D. Ismail, Joshua Pankrac, Emmanuel Ndashimye, Jessica L. Prodger, Melissa-Rose Abrahams, Jamie F. S. Mann, Andrew D. Redd, Eric J. Arts
Publikováno v:
Retrovirology, Vol 18, Iss 1, Pp 1-19 (2021)
Abstract HIV-1 persists in infected individuals despite years of antiretroviral therapy (ART), due to the formation of a stable and long-lived latent viral reservoir. Early ART can reduce the latent reservoir and is associated with post-treatment con
Externí odkaz:
https://doaj.org/article/21f8047523904318aa394b0f58bc8bdb
Autor:
Emmanuel Ndashimye, Eric J. Arts
Publikováno v:
International Journal of Infectious Diseases, Vol 105, Iss , Pp 298-303 (2021)
Background: Dolutegravir (DTG) is now recommended to all HIV infected adults, adolescents, and children of right age by WHO. The low cost of $75 per year for generic DTG-based combination, has allowed 3.9 million people living with HIV (PLWH) in low
Externí odkaz:
https://doaj.org/article/6a80ced15af64eb488e67b7b7df5370d
Autor:
Hiva Azizi, Jason P. Knapp, Yue Li, Alice Berger, Marc-Alexandre Lafrance, Jannie Pedersen, Marc-Antoine de la Vega, Trina Racine, Chil-Yong Kang, Jamie F. S. Mann, Jimmy D. Dikeakos, Gary Kobinger, Eric J. Arts
Publikováno v:
Vaccines, Vol 11, Iss 5, p 977 (2023)
Vesicular stomatitis virus (VSV) remains an attractive platform for a potential HIV-1 vaccine but hurdles remain, such as selection of a highly immunogenic HIV-1 Envelope (Env) with a maximal surface expression on recombinant rVSV particles. An HIV-1
Externí odkaz:
https://doaj.org/article/5fb10575b302437c965355e5448185ca