Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eric I. Danek"'
Autor:
Yi He, Marie-Anne Goyette, Jennifer Chapelle, Nadia Boufaied, Jalal Al Rahbani, Maribel Schonewolff, Eric I. Danek, William J. Muller, David P. Labbé, Jean-François Côté, Nathalie Lamarche-Vane
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112936- (2023)
Summary: Epithelial-to-mesenchymal transition (EMT) plays a crucial role in metastasis, which is the leading cause of death in breast cancer patients. Here, we show that Cdc42 GTPase-activating protein (CdGAP) promotes tumor formation and metastasis
Externí odkaz:
https://doaj.org/article/99945987e095410c96e9de7bda1ae234
Autor:
François Ferron, Zongli Li, Eric I Danek, Dahai Luo, Yeehwa Wong, Bruno Coutard, Violaine Lantez, Rémi Charrel, Bruno Canard, Thomas Walz, Julien Lescar
Publikováno v:
PLoS Pathogens, Vol 7, Iss 5, p e1002030 (2011)
Rift Valley fever virus (RVFV), a Phlebovirus with a genome consisting of three single-stranded RNA segments, is spread by infected mosquitoes and causes large viral outbreaks in Africa. RVFV encodes a nucleoprotein (N) that encapsidates the viral RN
Externí odkaz:
https://doaj.org/article/c0701c10373c4dde9a7dcba91d21a7cd
Autor:
Andreas D. Schenk, Philip J. Kranzusch, Bo Liang, Amal A. Rahmeh, Sean P. J. Whelan, Eric I. Danek, Thomas Walz
Publikováno v:
Proceedings of the National Academy of Sciences. 107:20075-20080
Nonsegmented negative-strand (NNS) RNA viruses initiate infection by delivering into the host cell a highly specialized RNA synthesis machine comprising the genomic RNA completely encapsidated by the viral nucleocapsid protein and associated with the
Autor:
Evelyne Bloch-Gallego, Eric I. Danek, Sarah McFarlane, Joseph Tcherkezian, Mayya Meriane, Nathalie Lamarche-Vane, Christine A. Webber, Ibtissem Triki
Publikováno v:
The Journal of Cell Biology
Netrin-1 acts as a chemoattractant molecule to guide commissural neurons (CN) toward the floor plate by interacting with the receptor deleted in colorectal cancer (DCC). The molecular mechanisms underlying Netrin-1–DCC signaling are still poorly ch
Autor:
Eric I. Danek, Nathalie Lamarche-Vane, Ibtissem Triki, Sylwia Wasiak, Natasha K. Hussain, Peter S. McPherson, Sarah Jenna
Publikováno v:
Journal of Biological Chemistry. 277:6366-6373
The Rho GTPases RhoA, Rac1, and Cdc42 play a major role in regulating the reorganization of the actin cytoskeleton. We recently identified CdGAP, a novel GTPase-activating protein with activity toward Rac1 and Cdc42. CdGAP consists of a N-terminal GA
Publikováno v:
The Journal of biological chemistry. 282(6)
Rho GTPases regulate a multitude of cellular processes from cytoskeletal reorganization to gene transcription and are negatively regulated by GTPase-activating proteins (GAPs). Cdc42 GTPase-activating protein (CdGAP) is a ubiquitously expressed GAP f
Publikováno v:
Biology of the cell. 98(8)
Background information. Rho GTPases regulate a wide range of cellular functions affecting both cell proliferation and cytoskeletal dynamics. They cycle between inactive GDP- and active GTP-bound states. This cycle is tightly regulated by GEFs (guanin
Publikováno v:
Molecular and cellular biology. 25(15)
Rho GTPases regulate multiple cellular processes affecting both cell proliferation and cytoskeletal dynamics. Their cycling between inactive GDP- and active GTP-bound states is tightly regulated by guanine nucleotide exchange factors and GTPase-activ
Autor:
Julien Lescar, Bruno Canard, François Ferron, Bruno Coutard, Dahai Luo, Yeehwa Wong, Rémi N. Charrel, Violaine Lantez, Eric I. Danek, Thomas Walz, Zongli Li
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 5, p e1002030 (2011)
PLoS Pathogens, Vol 7, Iss 5, p e1002030 (2011)
Rift Valley fever virus (RVFV), a Phlebovirus with a genome consisting of three single-stranded RNA segments, is spread by infected mosquitoes and causes large viral outbreaks in Africa. RVFV encodes a nucleoprotein (N) that encapsidates the viral RN