Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Eric I. Campos"'
Autor:
Mary E. McQuaid, Kashif Ahmed, Stephanie Tran, Justine Rousseau, Ranad Shaheen, Kristin D. Kernohan, Kyoko E. Yuki, Prerna Grover, Ema S. Dreseris, Sameen Ahmed, Lucie Dupuis, Jennifer Stimec, Mary Shago, Zuhair N. Al-Hassnan, Roch Tremblay, Philipp G. Maass, Michael D. Wilson, Eyal Grunebaum, Kym M. Boycott, François-Michel Boisvert, Sateesh Maddirevula, Eissa A. Faqeih, Fahad Almanjomi, Zaheer Ullah Khan, Fowzan S. Alkuraya, Philippe M. Campeau, Peter Kannu, Eric I. Campos, Hugo Wurtele
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
The eukaryotic CDC45/MCM2-7/GINS (CMG) helicase unwinds the DNA double helix during DNA replication. The GINS subcomplex is required for helicase activity and is, therefore, essential for DNA replication and cell viability. Here, we report the identi
Externí odkaz:
https://doaj.org/article/3826d777770e43a3ada9bdd9c34ba315
Autor:
William A. Scott, Eric I. Campos
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Histones are an integral part of chromatin and thereby influence its structure, dynamics, and functions. The effects of histone variants, posttranslational modifications, and binding proteins is therefore of great interest. From the moment that they
Externí odkaz:
https://doaj.org/article/ed2128cf1e3440f796a34acdf5b010c8
Autor:
William A Scott, Erum Z Dhanji, Boris J A Dyakov, Ema S Dreseris, Jonathon S Asa, Laura J Grange, Mila Mirceta, Christopher E Pearson, Grant S Stewart, Anne-Claude Gingras, Eric I Campos
Publikováno v:
PLoS Genetics, Vol 17, Iss 11, p e1009909 (2021)
The ATRX ATP-dependent chromatin remodelling/helicase protein associates with the DAXX histone chaperone to deposit histone H3.3 over repetitive DNA regions. Because ATRX-protein interactions impart functions, such as histone deposition, we used prox
Externí odkaz:
https://doaj.org/article/af68af506bd142f7b6d8a3e341ef58e4
Autor:
Robert Siddaway, Laura Canty, Sanja Pajovic, Scott Milos, Etienne Coyaud, Stefanie-Grace Sbergio, Arun Kumaran Vadivel Anguraj, Evan Lubanszky, Hwa Young Yun, Alessia Portante, Sheyenne Carette, Cunjie Zhang, Michael F. Moran, Brian Raught, Eric I. Campos, Cynthia Hawkins
Publikováno v:
Acta Neuropathologica. 144:1027-1048
Histone H3 mutations at amino acids 27 (H3K27M) and 34 (H3G34R) are recurrent drivers of pediatric-type high-grade glioma (pHGG). H3K27M mutations lead to global disruption of H3K27me3 through dominant negative PRC2 inhibition, while H3G34R mutations
Autor:
Monica J. Justice, Michiel Vermeulen, Eric I. Campos, Pascal W.T.C. Jansen, Travis Brooke-Bisschop, Lauren J. Tracey
PR domain–containing 14 (Prdm14) is a pluripotency regulator central to embryonic stem cell identity and primordial germ cell specification. Genomic regions containing PRDM14 are often amplified leading to misexpression in human cancer. Prdm14 expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5749fb53959da1a6fe462ce33e78d0
https://doi.org/10.1158/1541-7786.c.6541050
https://doi.org/10.1158/1541-7786.c.6541050
Autor:
Monica J. Justice, Michiel Vermeulen, Eric I. Campos, Pascal W.T.C. Jansen, Travis Brooke-Bisschop, Lauren J. Tracey
Mass spectrometry results listing LFQs, significance values and gene names.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4578ca3609660807fede434803aed5
https://doi.org/10.1158/1541-7786.22515342
https://doi.org/10.1158/1541-7786.22515342
Autor:
Monica J. Justice, Michiel Vermeulen, Eric I. Campos, Pascal W.T.C. Jansen, Travis Brooke-Bisschop, Lauren J. Tracey
Western blot results of 2.5% input from transfected HA-CBFA2T3 constructs shown at two exposures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261c7954de2faf222d479695419489b3
https://doi.org/10.1158/1541-7786.22515345
https://doi.org/10.1158/1541-7786.22515345
Autor:
Sima Khazaei, Carol C.L. Chen, Augusto Faria Andrade, Nisha Kabir, Pariya Azarafshar, Shahir M. Morcos, Josiane Alves França, Mariana Lopes, Peder J. Lund, Geoffroy Danieau, Samantha Worme, Lata Adnani, Nadine Nzirorera, Xiao Chen, Gayathri Yogarajah, Caterina Russo, Michele Zeinieh, Cassandra J. Wong, Laura Bryant, Steven Hébert, Bethany Tong, Tianna S. Sihota, Damien Faury, Evan Puligandla, Wajih Jawhar, Veronica Sandy, Mitra Cowan, Emily M. Nakada, Loydie A. Jerome-Majewska, Benjamin Ellezam, Carolina Cavalieri Gomes, Jonas Denecke, Davor Lessel, Marie T. McDonald, Carolyn E. Pizoli, Kathryn Taylor, Benjamin T. Cocanougher, Elizabeth J. Bhoj, Anne-Claude Gingras, Benjamin A. Garcia, Chao Lu, Eric I. Campos, Claudia L. Kleinman, Livia Garzia, Nada Jabado
Publikováno v:
Cell. 186:1162-1178.e20
Autor:
Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins
Publikováno v:
Molecular & Cellular Proteomics. 21:100411
Chromatin structure, transcription, DNA replication, and repair are regulated via locus-specific incorporation of histone variants and posttranslational modifications that guide effector chromatin-binding proteins. Here we report unbiased, quantitati
Autor:
Anne-Claude Gingras, Wesley Wei Qian, Nader Alerasool, Zhen Yuan Lin, Jian Peng, Mikko Taipale, Brett Larsen, Jessica Lacoste, Eric I. Campos, Benjamin L. Piette, Stephanie Tran, Mandy H. Y. Lam
Publikováno v:
Molecular Cell. 81:2549-2565.e8
Hsp70s comprise a deeply conserved chaperone family that has a central role in maintaining protein homeostasis. In humans, Hsp70 client specificity is provided by 49 different co-factors known as J domain proteins (JDPs). However, the cellular functi