Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Eric Huseby"'
Autor:
Nicholas A Spidale, Nidhi Malhotra, Michela Frascoli, Katelyn Sylvia, Bing Miu, Coral Freeman, Brian D Stadinski, Eric Huseby, Joonsoo Kang
Publikováno v:
eLife, Vol 9 (2020)
Atopic Dermatitis (AD) is a T cell-mediated chronic skin disease and is associated with altered skin barrier integrity. Infants with mutations in genes involved in tissue barrier fitness are predisposed towards inflammatory diseases, but most do not
Externí odkaz:
https://doaj.org/article/6be039ecae2945efaff16225bb05359e
Publikováno v:
PLoS Biology, Vol 2, Iss 4, p E90 (2004)
The use of peptide libraries for the identification and characterization of T cell antigen peptide epitopes and mimotopes has been hampered by the need to form complexes between the peptides and an appropriate MHC molecule in order to construct a com
Externí odkaz:
https://doaj.org/article/1ecbc3bbb3eb4315affde0ba412c4607
Autor:
Emma Teixeiro, Eric Huseby
Publikováno v:
Sci Signal
αβ T cells are critical components of the adaptive immune system and are capable of inducing sterilizing immunity after pathogen infection and eliminating transformed tumor cells. The development and function of T cells are controlled through the T
Autor:
Michael C. Jones, Catherine Castonguay, Padma P. Nanaware, Grant C. Weaver, Brian Stadinski, Olivia A. Kugler-Umana, Eric Huseby, Lawrence J. Stern, Priyadharshini Devarajan, Susan L. Swain
The impact of initial peptide antigen affinity for TCR in driving memory fate has been studied previously, however its contributions when effectors contract to memory is unclear. To become memory, effector CD4 T cells must recognize antigen at 5-8 da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e6634c0c50ff900a9b79c70a5e7bba2
https://doi.org/10.1101/2022.05.09.491158
https://doi.org/10.1101/2022.05.09.491158
Publikováno v:
Cellular and Molecular Immunology
The diversity of antigen receptors and the specificity it underlies are the hallmarks of the cellular arm of the adaptive immune system. T and B lymphocytes are indeed truly unique in their ability to generate receptors capable of recognizing virtual
Publikováno v:
European journal of immunology. 34(5)
The purpose of this Commentary is to put into modern-day perspective Jerne's hypothesis that antigen receptors encoded in the genome have been evolutionarily selected for their ability to react with major histocompatibility proteins and that the proc
Publikováno v:
The Journal of Immunology. 188:69.8-69.8
The activation of the CD4+ T cell immune response to pathogens is determined by the interaction between the T cell receptor and its cognate pathogen-derived peptide presented by MHC-II molecules on antigen-presenting cells (APCs). In vitro, whether a