Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Eric Hanse"'
Autor:
Linda Engström Ruud, Ferran Font-Gironès, Joanna Zajdel, Lara Kern, Júlia Teixidor-Deulofeu, Louise Mannerås-Holm, Alba Carreras, Barbara Becattini, Andreas Björefeldt, Eric Hanse, Henning Fenselau, Giovanni Solinas, Jens C. Brüning, Thomas F. Wunderlich, Fredrik Bäckhed, Johan Ruud
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 113960- (2024)
Summary: GFRAL-expressing neurons actuate aversion and nausea, are targets for obesity treatment, and may mediate metformin effects by long-term GDF15-GFRAL agonism. Whether GFRAL+ neurons acutely regulate glucose and energy homeostasis is, however,
Externí odkaz:
https://doaj.org/article/aa3d323435254270b9519bdc32c22457
Autor:
Agnès Espana, Henrik Seth, Julie Jézéquel, Tingting Huang, Delphine Bouchet, Marylin Lepleux, Hélène Gréa, Karl Bechter, Marion Schneider, Eric Hanse, Laurent Groc
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract A dysfunction of the glutamatergic transmission, especially of the NMDA receptor (NMDAR), constitutes one of the main biological substrate of psychotic disorders, such as schizophrenia. The NMDAR signaling hypofunction, through genetic and/o
Externí odkaz:
https://doaj.org/article/00e073c8e2e1486480d47e7131444dcb
Autor:
Julia Izsak, Henrik Seth, Margarita Iljin, Stephan Theiss, Hans Ågren, Keiko Funa, Ludwig Aigner, Eric Hanse, Sebastian Illes
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Lithium salts are used as mood-balancing medication prescribed to patients suffering from neuropsychiatric disorders, such as bipolar disorder and major depressive disorder. Lithium salts cross the blood-brain barrier and reach the brain par
Externí odkaz:
https://doaj.org/article/dfe9a2628cbc46949c5e6716415a69af
Autor:
Julia Izsak, Dzeneta Vizlin-Hodzic, Margarita Iljin, Joakim Strandberg, Janusz Jadasz, Thomas Olsson Bontell, Stephan Theiss, Eric Hanse, Hans Ågren, Keiko Funa, Sebastian Illes
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Persistent neural stem cell (NSC) proliferation is, among others, a hallmark of immaturity in human induced pluripotent stem cell (hiPSC)-based neural models. TGF-β1 is known to regulate NSCs in vivo during embryonic development in rodents. Here we
Externí odkaz:
https://doaj.org/article/66d945539ed34be099807ded70c1bc61
Autor:
Julia Izsak, Henrik Seth, Mats Andersson, Dzeneta Vizlin-Hodzic, Stephan Theiss, Eric Hanse, Hans Ågren, Keiko Funa, Sebastian Illes
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Reproducibly generating human induced pluripotent stem cell-based functional neuronal circuits, solely obtained from single individuals, poses particular challenges to achieve personalized and patient specific functional neuronal in vitro models. A h
Externí odkaz:
https://doaj.org/article/dcf07ab44f4e414398710e2b811e1c71
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 11 (2019)
Advanced imaging techniques have revealed that synapses contain nanomodules in which pre- and post-synaptic molecules are brought together to form an integrated subsynaptic component for vesicle release and transmitter reception. Based on data from a
Externí odkaz:
https://doaj.org/article/16b68077b0cf41169781e1aae0cc31cd
Publikováno v:
Frontiers in Neural Circuits, Vol 12 (2018)
The cerebrospinal fluid (CSF) occupies the brain’s ventricles and subarachnoid space and, together with the interstitial fluid (ISF), forms a continuous fluidic network that bathes all cells of the central nervous system (CNS). As such, the CSF is
Externí odkaz:
https://doaj.org/article/c1b0cacbdb74494480582a6907075d9d
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34474 (2012)
Agonist-induced internalization of transmembrane receptors is a widespread biological phenomenon that also may serve as a mechanism for synaptic plasticity. Here we show that the agonist AMPA causes a depression of AMPA receptor (AMPAR) signaling at
Externí odkaz:
https://doaj.org/article/e9f574e1c440463b877885c72dc36407
Publikováno v:
European Journal of Neuroscience. 54:4838-4862
When activated at low frequencies (0.1-1 Hz), second postnatal week synapses onto the most distal part of the apical dendritic tree (stratum lacunosum-moleculare) of rat hippocampal CA1 pyramidal cells display a frequency-dependent synaptic depressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f73f4a72886afb4896ecd315a0e55b5a
https://doi.org/10.1111/ejn.15357
https://doi.org/10.1111/ejn.15357
Publikováno v:
Neuroscience. 490
Antisecretory Factor (AF) is an endogenous peptide known for its powerful antisecretory and anti-inflammatory properties. We have previously shown that AF also acts as a neuromodulator of GABAergic synaptic transmission in rat hippocampus in a way th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc12ebf5fa418596c1d06f19833df576
https://pubmed.ncbi.nlm.nih.gov/35276306
https://pubmed.ncbi.nlm.nih.gov/35276306