Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Eric Hajduch"'
Autor:
Sarah Ali-Berrada, Jeanne Guitton, Sophie Tan-Chen, Anna Gyulkhandanyan, Eric Hajduch, Hervé Le Stunff
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12720 (2023)
Sphingolipids are a family of lipid molecules produced through different pathways in mammals. Sphingolipids are structural components of membranes, but in response to obesity, they are implicated in the regulation of various cellular processes, inclu
Externí odkaz:
https://doaj.org/article/3faacb01e3204a0eaac2408f27404f7e
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/10c1a0cde8784f04a0c78aa1d12ae0b8
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Sphingolipids represent one of the major classes of eukaryotic lipids. They play an essential structural role, especially in cell membranes where they also possess signaling properties and are capable of modulating multiple cell functions, such as ap
Externí odkaz:
https://doaj.org/article/8e4288619d3b4784a173d5af374bf0b2
Autor:
Mélanie Campana, Lara Bellini, Claude Rouch, Latif Rachdi, Nicolas Coant, Noémie Butin, Cécile L. Bandet, Erwann Philippe, Kelly Meneyrol, Nadim Kassis, Julien Dairou, Eric Hajduch, Benoit Colsch, Christophe Magnan, Hervé Le Stunff
Publikováno v:
Molecular Metabolism, Vol 8, Iss , Pp 23-36 (2018)
Objectives: Hypothalamic lipotoxicity has been shown to induce central insulin resistance and dysregulation of glucose homeostasis; nevertheless, elucidation of the regulatory mechanisms remains incomplete. Here, we aimed to determine the role of de
Externí odkaz:
https://doaj.org/article/36162c8527874fe1a2f4d78629f38b0c
Autor:
Isabella Bonilha, Eric Hajduch, Beatriz Luchiari, Wilson Nadruz, Wilfried Le Goff, Andrei C. Sposito
Publikováno v:
Metabolites, Vol 11, Iss 12, p 807 (2021)
Type 2 diabetes mellitus and insulin resistance feature substantial modifications of the lipoprotein profile, including a higher proportion of smaller and denser low-density lipoprotein (LDL) particles. In addition, qualitative changes occur in the c
Externí odkaz:
https://doaj.org/article/084af1e369064e1a92e3f32dc3b4935f
Autor:
Jeanne Guitton, Cécile L. Bandet, Mohamed L. Mariko, Sophie Tan-Chen, Olivier Bourron, Yacir Benomar, Eric Hajduch, Hervé Le Stunff
Publikováno v:
Cells, Vol 9, Iss 7, p 1682 (2020)
Obesity is a pathophysiological condition where excess free fatty acids (FFA) target and promote the dysfunctioning of insulin sensitive tissues and of pancreatic β cells. This leads to the dysregulation of glucose homeostasis, which culminates in t
Externí odkaz:
https://doaj.org/article/2ab8398c59284279b40f87c07b2f11ce
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 3, p 479 (2019)
Insulin-resistance is a characteristic feature of type 2 diabetes (T2D) and plays a major role in the pathogenesis of this disease. Skeletal muscles are quantitatively the biggest glucose users in response to insulin and are considered as main target
Externí odkaz:
https://doaj.org/article/c52b37eeaf9e4430940ee7020e4a058a
Autor:
Cédric M. Blouin, Soazig Le Lay, Anita Eberl, Harald C. Köfeler, Ida Chiara Guerrera, Christophe Klein, Xavier Le Liepvre, Françoise Lasnier, Olivier Bourron, Jean-François Gautier, Pascal Ferré, Eric Hajduch, Isabelle Dugail
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 5, Pp 945-956 (2010)
Caveolins form plasmalemnal invaginated caveolae. They also locate around intracellular lipid droplets but their role in this location remains unclear. By studying primary adipocytes that highly express caveolin-1, we characterized the impact of cave
Externí odkaz:
https://doaj.org/article/3c6c41d0431c4d0ba534a69245d41d89
Autor:
Rana Mahfouz, Rhéa Khoury, Agnieszka Blachnio-Zabielska, Sophie Turban, Nicolas Loiseau, Christopher Lipina, Clare Stretton, Olivier Bourron, Pascal Ferré, Fabienne Foufelle, Harinder S Hundal, Eric Hajduch
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101865 (2014)
Ceramides are known to promote insulin resistance in a number of metabolically important tissues including skeletal muscle, the predominant site of insulin-stimulated glucose disposal. Depending on cell type, these lipid intermediates have been shown
Externí odkaz:
https://doaj.org/article/def06baf965243abac56d022f12b7e5c
Autor:
Francesca Nardi, Christopher Lipina, David Magill, Rima Hage Hassan, Eric Hajduch, Alexander Gray, Harinder S Hundal
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92255 (2014)
Reduced skeletal muscle insulin sensitivity is a feature associated with sustained exposure to excess saturated fatty acids (SFA), whereas mono and polyunsaturated fatty acids (MUFA and PUFA) not only improve insulin sensitivity but blunt SFA-induced
Externí odkaz:
https://doaj.org/article/5c070e7e66a440cd95fd175d691b8bc5