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pro vyhledávání: '"Eric H.L. Lee"'
Autor:
Eric H.L. Lee, Raj Chari B.C., Andy Lam, Raymond T. Ng, John Yee, John English, Kenneth G. Evans, Calum Macaulay, Stephen Lam, Wan L. Lam
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 2 (2008)
Disruptions of beta-catenin and the canonical Wnt pathway are well documented in cancer. However, little is known of the non-canonical branch of the Wnt pathway. In this study, we investigate the transcript level patterns of genes in the Wnt pathway
Externí odkaz:
https://doaj.org/article/b423f00c9bb946509463560d0e84c3ac
Autor:
Jacky Chung, Mindy A. Maynard, Joan W. Conaway, Eric H.L. Lee, Heng Qi, Yukihiro Kondo, Shuntaro Hara, Michael Ohh, Ronald C. Conaway
Publikováno v:
Journal of Biological Chemistry. 278:11032-11040
Functional inactivation of the von Hippel-Lindau (VHL) tumor suppressor protein is the cause of familial VHL disease and sporadic kidney cancer. The VHL gene product (pVHL) is a component of an E3 ubiquitin ligase complex that targets the hypoxia-ind