Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Eric H. Karunanayake"'
Publikováno v:
Breast Cancer: Targets and Therapy. 11:71-80
Cancer is a socioeconomical burden in any nation. Out of that, breast cancer is identified as the most common malignancy worldwide among women irrespective of age. As women are an important segment in a community, the weakening of their strength towa
Autor:
Kanchana S, Senanayake, Jonas, Söderberg, Aleksei, Põlajev, Maja, Malmberg, Eric H, Karunanayake, Kamani H, Tennekoon, Sameera R, Samarakoon, Erik, Bongcam-Rudloff, Adnan, Niazi
Publikováno v:
Genome Biology and Evolution
Here we present the draft genome sequence of Setaria digitata, a parasitic nematode affecting cattle. Due to its similarity to Wuchereria bancrofti, the parasitic nematode that causes lymphatic filariasis in humans, S. digitata has been used as a mod
Autor:
Achyut Adhikari, Eric H. Karunanayake, Meran Keshawa Ediriweera, Sameera R. Samarakoon, Kamani H. Tennekoon, Ira Thabrew, Panchima Jayarathna
Publikováno v:
Phytochemistry Letters. 24:114-119
Campnosperma zeylanica Thwaites is a plant endemic to Sri Lanka. Bio-assay guided fractionation of the hexane extract of leaves of C. zeylanica yielded three new cytotoxic compounds identified as alkyl-hydroxycyclohexenones; Campnospermenone A, Campn
Autor:
Eric H. Karunanayake, Arman Esfandiari, Ahmed Khairallah Mahdi, C-E Wu, S.T. de Silva, John Lunec, Vahinipriya Manoharan, M Zanjirband, Kamani H. Tennekoon
Publikováno v:
Cancer Research. 77:P3-07
Background The tumor suppressor p53 is a central hub in molecular signaling pathways that control the integrity of the human genome. The p53 protein functions as a transcription factor and increases the expression of many cellular genes which contrib
Autor:
Eric H. Karunanayake, Ananda Wijayasiri, Indrani Amarasinghe, Chrishani Rodrigo, Kamani H. Tennekoon, Kanishka De Silva
Publikováno v:
Endocrine Journal. 64:393-401
Leptin and visfatin are implicated in breast cancer risk but studies accounting for bioavailability of leptin are sparse. Reports on the association of leptin gene (LEP) and leptin receptor gene (LEPR) polymorphisms with breast cancer are also incons
Autor:
John Lunec, Sameera Vishwakula, P. Angunawela, Ahamed Ilyas Ahamed Imthikab, Vahinipriya Manoharan, Kamani H. Tennekoon, Sumadee De Silva, Kanishka De Silva, Eric H. Karunanayake
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-15 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-15 (2020)
Background Breast cancer (BC) is known to be the most common malignancy in females whereas colorectal cancer (CRC) incidence also higher in both genders in Sri Lanka. TP53 is an important tumour suppressor gene and its somatic mutations are reported
Autor:
Kamani H. Tennekoon, Ira Thabrew, Eric H. Karunanayake, Sameera R. Samarakoon, Meran Keshawa Ediriweera, Egodage Dilip de Silva, Panchima Jayarathna
Publikováno v:
European Journal of Medicinal Plants. 15:1-15
Autor:
John Lunec, Eric H. Karunanayake, P. Angunawela, Sumadee De Silva, Vahinipriya Manoharan, Kanishka De Silva, Kamani H. Tennekoon
Publikováno v:
Molecular Medicine Reports
Head and neck cancer (HNC) is the leading cancer in Sri Lankan males and second most common cancer among Sri Lankan females. This is the first study, to the best of our knowledge, that has focused on investigating the association between TP53 somatic
Autor:
Sameera R. Samarakoon, Eric H. Karunanayake, Karthika Mayan, Kamani H. Tennekoon, Nirupa Nagaratnam
Publikováno v:
Bioinformation
Human lymphatic filariasis (HLF) is a neglected tropical disease which threatens nearly 1.4 billion people in 73 countries worldwide. Wuchereria bancrofti is the major causative agent of HLF and it closely resembles cattle filarial parasite Setaria d
Autor:
Wasana Rodrigo, Eric H. Karunanayake, Y.I.N. Silva Gunawardene, Ranil Samantha Dassanayake, O. Vds. J. Weerasena
Publikováno v:
Asian Pacific Journal of Tropical Medicine. 7(2):85-92
Objective To clone, express and purify a putative parasitic nematode specific protein of Setaria digitata (S. digitata) , filarial nematode that infects livestock and cause significant economic losses in Far East and Asia to be used for structural an