Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Eric H. Baehrecke"'
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102713- (2023)
Summary: Large quantities of developmentally synchronized pupal intestines are required for biochemistry experiments. Here, we present a protocol for the mass isolation of staged pupal intestines during Drosophila melanogaster development based on bu
Externí odkaz:
https://doaj.org/article/ffd60f98ae8c4c6f9f6045c500c44491
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100473- (2021)
Summary: This protocol describes the embedding and processing of Drosophila pupae in paraffin to monitor tissue changes during development. Although multiple methods are available to evaluate developmental changes in Drosophila embryos, imaging detai
Externí odkaz:
https://doaj.org/article/efac2bf690fd469ba32b72889f1315cf
Autor:
Anubhab Nandy, Lin Lin, Panagiotis D. Velentzas, Louisa P. Wu, Eric H. Baehrecke, Neal Silverman
Publikováno v:
Cell Reports, Vol 25, Iss 8, Pp 2110-2120.e3 (2018)
Summary: Macroautophagy and cell death both contribute to innate immunity, but little is known about how these processes integrate. Drosophila larval salivary glands require autophagy for developmentally programmed cell death, and innate immune signa
Externí odkaz:
https://doaj.org/article/0bea2c9364e94c909506906ec0df6901
Publikováno v:
Cell Death & Differentiation. 29:2275-2287
Autophagy targets cytoplasmic materials for degradation, and influences cell health. Alterations in Atg6/Beclin-1, a key regulator of autophagy, are associated with multiple diseases. While the role of Atg6 in autophagy regulation is heavily studied,
Publikováno v:
Dev Biol
Pulses of the steroid hormone ecdysone act through transcriptional cascades to direct the major developmental transitions during the Drosophila life cycle. These include the prepupal ecdysone pulse, which occurs 10 hours after pupariation and trig
Autor:
Elizabeth A. Allen, Eric H. Baehrecke
Publikováno v:
Cell Death Differ
Macroautophagy (autophagy) delivers intracellular constituents to the lysosome to promote catabolism. During development in multiple organisms, autophagy mediates various cellular processes, including survival during starvation, programmed cell death
Autor:
Lorenzo Galluzzi, Hans-Uwe Simon, Augustine M.K. Choi, Qing Zhong, Patrice Codogno, Junying Yuan, Alexandra Stolz, Zvulun Elazar, Eeva-Liisa Eskelinen, Douglas R. Green, José Manuel Bravo-San Pedro, David A. Gewirtz, Anne Simonsen, Sharon A. Tooze, Frank Madeo, María Isabel Colombo, Terje Johansen, Ravi K. Amaravadi, Giulia Petroni, Nicholas T. Ktistakis, Luca Scorrano, Marja Jäättelä, David C. Rubinsztein, Laura Santambrogio, Ivan Dikic, Kay F. Macleod, Kevin M. Ryan, Claudine Kraft, Gian Maria Fimia, Charleen T. Chu, Jennifer Martinez, Carlos López-Otín, Junichi Sadoshima, Gábor Juhász, Vassiliki Karantza, Malene Hansen, Zhenyu Yue, Ken Cadwell, Ana Maria Cuervo, Francesco Cecconi, Mary E. Choi, Eric H. Baehrecke, Patricia Boya, Vojo Deretic, Nektarios Tavernarakis, Alicia Meléndez, Josef M. Penninger, Mauro Piacentini, Tamotsu Yoshimori, Fulvio Reggiori, Sharad Kumar, Andrea Ballabio, Anna Katharina Simon, Federico Pietrocola, Rushika M. Perera, Guido Kroemer, Christian Münz, Noboru Mizushima, Daniel J. Klionsky
Publikováno v:
The EMBO Journal
Klionsky, D J, Petroni, G, Amaravadi, R K, Baehrecke, E H, Ballabio, A, Boya, P, Bravo-San Pedro, J M, Cadwell, K, Cecconi, F, Choi, A M K, Choi, M E, Chu, C T, Codogno, P, Colombo, MI, Cuervo, A M, Deretic, V, Dikic, I, Elazar, Z, Eskelinen, E L, Fimia, G M, Gewirtz, D A, Green, D R, Hansen, M, Jäättelä, M, Johansen, T, Juhász, G, Karantza, V, Kraft, C, Kroemer, G, Ktistakis, N T, Kumar, S, Lopez-Otin, C, Macleod, K F, Madeo, F, Martinez, J, Meléndez, A, Mizushima, N, Münz, C, Penninger, J M, Perera, RM, Piacentini, M, Reggiori, F, Rubinsztein, D C, Ryan, KM, Sadoshima, J, Santambrogio, L, Scorrano, L, Simon, H U, Simon, A K, Simonsen, A, Stolz, A, Tavernarakis, N, Tooze, S A, Yoshimori, T, Yuan, J, Yue, Z, Zhong, Q, Galluzzi, L & Pietrocola, F 2021, ' Autophagy in major human diseases ', EMBO Journal, vol. 40, e108863 . https://doi.org/10.15252/embj.2021108863
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Klionsky, D J, Petroni, G, Amaravadi, R K, Baehrecke, E H, Ballabio, A, Boya, P, Bravo-San Pedro, J M, Cadwell, K, Cecconi, F, Choi, A M K, Choi, M E, Chu, C T, Codogno, P, Colombo, M I, Cuervo, A M, Deretic, V, Dikic, I, Elazar, Z, Eskelinen, E-L, Fimia, G M, Gewirtz, D A, Green, D R, Hansen, M, Jäättelä, M, Johansen, T, Juhász, G, Karantza, V, Kraft, C, Kroemer, G, Ktistakis, N T, Kumar, S, Lopez-Otin, C, Macleod, K F, Madeo, F, Martinez, J, Meléndez, A, Mizushima, N, Münz, C, Penninger, J M, Perera, R M, Piacentini, M, Reggiori, F, Rubinsztein, D C, Ryan, K M, Sadoshima, J, Santambrogio, L, Scorrano, L, Simon, H-U, Simon, A K, Simonsen, A, Stolz, A, Tavernarakis, N, Tooze, S A, Yoshimori, T, Yuan, J, Yue, Z, Zhong, Q, Galluzzi, L & Pietrocola, F 2021, ' Autophagy in major human diseases ', The EMBO Journal, vol. 40, no. 19, pp. e108863 . https://doi.org/10.15252/embj.2021108863
Klionsky, Daniel J; Petroni, Giulia; Amaravadi, Ravi K; Baehrecke, Eric H; Ballabio, Andrea; Boya, Patricia; Bravo-San Pedro, José Manuel; Cadwell, Ken; Cecconi, Francesco; Choi, Augustine M K; Choi, Mary E; Chu, Charleen T; Codogno, Patrice; Colombo, Maria Isabel; Cuervo, Ana Maria; Deretic, Vojo; Dikic, Ivan; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Fimia, Gian Maria; ... (2021). Autophagy in major human diseases. The EMBO journal, 40(19), e108863. EMBO Press 10.15252/embj.2021108863
EMBO Reports
Klionsky, D J, Petroni, G, Amaravadi, R K, Baehrecke, E H, Ballabio, A, Boya, P, Bravo-San Pedro, J M, Cadwell, K, Cecconi, F, Choi, A M K, Choi, M E, Chu, C T, Codogno, P, Colombo, MI, Cuervo, A M, Deretic, V, Dikic, I, Elazar, Z, Eskelinen, E L, Fimia, G M, Gewirtz, D A, Green, D R, Hansen, M, Jäättelä, M, Johansen, T, Juhász, G, Karantza, V, Kraft, C, Kroemer, G, Ktistakis, N T, Kumar, S, Lopez-Otin, C, Macleod, K F, Madeo, F, Martinez, J, Meléndez, A, Mizushima, N, Münz, C, Penninger, J M, Perera, RM, Piacentini, M, Reggiori, F, Rubinsztein, D C, Ryan, KM, Sadoshima, J, Santambrogio, L, Scorrano, L, Simon, H U, Simon, A K, Simonsen, A, Stolz, A, Tavernarakis, N, Tooze, S A, Yoshimori, T, Yuan, J, Yue, Z, Zhong, Q, Galluzzi, L & Pietrocola, F 2021, ' Autophagy in major human diseases ', EMBO Journal, vol. 40, e108863 . https://doi.org/10.15252/embj.2021108863
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Klionsky, D J, Petroni, G, Amaravadi, R K, Baehrecke, E H, Ballabio, A, Boya, P, Bravo-San Pedro, J M, Cadwell, K, Cecconi, F, Choi, A M K, Choi, M E, Chu, C T, Codogno, P, Colombo, M I, Cuervo, A M, Deretic, V, Dikic, I, Elazar, Z, Eskelinen, E-L, Fimia, G M, Gewirtz, D A, Green, D R, Hansen, M, Jäättelä, M, Johansen, T, Juhász, G, Karantza, V, Kraft, C, Kroemer, G, Ktistakis, N T, Kumar, S, Lopez-Otin, C, Macleod, K F, Madeo, F, Martinez, J, Meléndez, A, Mizushima, N, Münz, C, Penninger, J M, Perera, R M, Piacentini, M, Reggiori, F, Rubinsztein, D C, Ryan, K M, Sadoshima, J, Santambrogio, L, Scorrano, L, Simon, H-U, Simon, A K, Simonsen, A, Stolz, A, Tavernarakis, N, Tooze, S A, Yoshimori, T, Yuan, J, Yue, Z, Zhong, Q, Galluzzi, L & Pietrocola, F 2021, ' Autophagy in major human diseases ', The EMBO Journal, vol. 40, no. 19, pp. e108863 . https://doi.org/10.15252/embj.2021108863
Klionsky, Daniel J; Petroni, Giulia; Amaravadi, Ravi K; Baehrecke, Eric H; Ballabio, Andrea; Boya, Patricia; Bravo-San Pedro, José Manuel; Cadwell, Ken; Cecconi, Francesco; Choi, Augustine M K; Choi, Mary E; Chu, Charleen T; Codogno, Patrice; Colombo, Maria Isabel; Cuervo, Ana Maria; Deretic, Vojo; Dikic, Ivan; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Fimia, Gian Maria; ... (2021). Autophagy in major human diseases. The EMBO journal, 40(19), e108863. EMBO Press 10.15252/embj.2021108863
EMBO Reports
Autophagy is a core molecular pathway for the preservation of cellular and organismal homeostasis. Pharmacological and genetic interventions impairing autophagy responses promote or aggravate disease in a plethora of experimental models. Consistently
Publikováno v:
Current Biology. 32:1262-1274.e4
Autophagy targets cytoplasmic materials for degradation and influences cell health. Organelle contact and trafficking systems provide membranes for autophagosome formation, but how different membrane systems are selected for use during autophagy rema
Publikováno v:
Curr Biol
Mutations in Vps13D cause defects in autophagy, clearance of mitochondria, and human movement disorders. Here, we discover that Vps13D functions in a pathway downstream of Vmp1 and upstream of Marf/Mfn2. Like vps13d, vmp1 mutant cells exhibit defects
Autor:
Dragan Maric, Gil Kanfer, William A. Prinz, Hetal V. Shah, Eric H. Baehrecke, Heather Baldwin, Richard J. Youle, Chunxin Wang, Norbert Brüggemann, Allyson L. Anding, Antonio Velayos-Baeza, Marija Dulovic-Mahlow
Publikováno v:
The Journal of Cell Biology
The VPS13 proteins (VPS13A–D) are thought to mediate lipid transport between organelles and are linked to distinct neurological disorders in humans. Baldwin et al. found that, in addition to known involvement in mitochondrial morphology, VPS13D is